PT110896A - Forma amorfa de trifenatato de vilanterol e processos para a preparação da mesma - Google Patents

Forma amorfa de trifenatato de vilanterol e processos para a preparação da mesma

Info

Publication number
PT110896A
PT110896A PT11089617A PT11089617A PT110896A PT 110896 A PT110896 A PT 110896A PT 11089617 A PT11089617 A PT 11089617A PT 11089617 A PT11089617 A PT 11089617A PT 110896 A PT110896 A PT 110896A
Authority
PT
Portugal
Prior art keywords
processes
preparing
vilanterol triphenate
shape form
triphenate
Prior art date
Application number
PT11089617A
Other languages
English (en)
Other versions
PT110896B (pt
Inventor
Sobral Luis
Lourenço Nuno
Fernandes Joana
Original Assignee
Hovione Farm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Farm Sa filed Critical Hovione Farm Sa
Priority to PT110896A priority Critical patent/PT110896B/pt
Publication of PT110896A publication Critical patent/PT110896A/pt
Publication of PT110896B publication Critical patent/PT110896B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
    • C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

A PRESENTE INVENÇÃO REFERE-SE A UMA FORMA AMORFA DE TRIFENATATO DE VILANTEROL, PROCESSOS PARA A SUA PREPARAÇÃO E O SEU USO NUMA COMPOSIÇÃO FARMACÊUTICA PARA O TRATAMENTO DE DOENÇAS RESPIRATÓRIAS, PARTICULARMENTE PARA O TRATAMENTO DA ASMA E DA DOENÇA PULMONAR OBSTRUTIVA CRÓNICA. A FORMA AMORFA DE TRIFENATATO DE VILANTEROL DA PRESENTE INVENÇÃO SURPREENDENTEMENTE APRESENTA PROPRIEDADES DE ESTABILIDADE COMPARÁVEIS À FORMA CRISTALINA CONHECIDA, COM O MESMO EFEITO FARMACÊUTICO PELO QUE PODE SER UTILIZADA EM FORMULAÇÕES FARMACÊUTICAS ALTERNATIVAS.
PT110896A 2017-07-19 2017-07-19 Forma amorfa de trifenatato de vilanterol e processos para a preparação da mesma PT110896B (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PT110896A PT110896B (pt) 2017-07-19 2017-07-19 Forma amorfa de trifenatato de vilanterol e processos para a preparação da mesma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT110896A PT110896B (pt) 2017-07-19 2017-07-19 Forma amorfa de trifenatato de vilanterol e processos para a preparação da mesma

Publications (2)

Publication Number Publication Date
PT110896A true PT110896A (pt) 2019-02-05
PT110896B PT110896B (pt) 2021-05-06

Family

ID=68422594

Family Applications (1)

Application Number Title Priority Date Filing Date
PT110896A PT110896B (pt) 2017-07-19 2017-07-19 Forma amorfa de trifenatato de vilanterol e processos para a preparação da mesma

Country Status (1)

Country Link
PT (1) PT110896B (pt)

Also Published As

Publication number Publication date
PT110896B (pt) 2021-05-06

Similar Documents

Publication Publication Date Title
BR112016022598A8 (pt) composição aerossol farmacêutica na forma de um pó seco para liberação pulmonar, forma de dosagem unitária, pacote farmacêutico, kit e uso
BR112015024411A2 (pt) desaza-purinonas macrocíclicas para o tratamento de infeções virais
CL2018001089A1 (es) Sales de valbenazina y polimorfos de las mismas.
BR112017018368A2 (pt) composições contendo rna para o tratamento de doenças tumorais
BR112015020118A2 (pt) derivados de 2-aminopirimidina para o tratamento de infecções virais
BR112018004532A2 (pt) uso de akkermansia pasteurizado para o tratamento de distúrbios metabólicos
BR112019006463A2 (pt) composição oral de canabinoides extraídos e métodos de uso da mesma
BR112019008458A2 (pt) 1,2,4-triazolonas 2,4,5-trisubstituídas.
BR112017012327A2 (pt) benzamidas substituídas por 1,3-tiazol-2-il.
NI201700101A (es) Composiciones farmacéuticas que comprenden n - (3, 5 - dimetoxifenil) - n'- (1-metiletil) - n - [3-(1-metil-1h-pirazol-4-il) quinoxalina-6-il]etano-1,2-diamina
MX2019007587A (es) Composicion oftalmica para el tratamiento de la enfermedad del ojo seco.
BR112015011403A2 (pt) uso de akkermansia para o tratamento de distúrbios metabólicos
BR112015020302A2 (pt) derivado de pirazol
MX2019012847A (es) Compuestos de c5-anilinoquinazolina y su uso en el tratamiento del cancer.
MX2016011810A (es) Composiciones farmaceuticas de compuestos terapeuticamente activos y sus metodos de uso.
BR112015007814A2 (pt) diagnóstico, prevenção e tratamento de doenças da articulação
BR112016007536A2 (pt) compostos, composições e utilizações correspondentes, para a prevenção e/ou o tratamento de dislipidemias
BR112016028845A2 (pt) composto, composição farmacêutica e uso de um composto
CY1124115T1 (el) Η χρηση τριβενζοϊκου γλυκερυλιου που περιεχει συνθεση σε νευροεκφυλιστικες διαταραχες
UY38228A (es) Compuestos de triazolopirimidina y su uso en el tratamiento del cáncer
PT3820446T (pt) Composições farmacêuticas que compreendem rpl554 em hfa-134a para administração mediante inalação
BR112021011368A2 (pt) Cocristal de cetoprofeno, composições compreendendo o mesmo, processo para a sua produção e usos dos mesmos
BR112019005318A2 (pt) compostos de aza-indazol para uso em lesões no tendão e/ou ligamento
PT110209A (pt) Formas polimórficas de trifenatato de vilanterol e processos para a preparação das mesmas.
BR112017021583A2 (pt) métodos para o tratamento de transtornos inflamatórios

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 20190131

FG3A Patent granted, date of granting

Effective date: 20210503