PT1252155E - Solvato de etanol de (-)-cis-2-(2-clorofenil)-5,7-di-hidroxi-8-[4r-(3s-hidroxi-1-metil)piperidinil]-4h-1-bezopiran-4-ona - Google Patents

Solvato de etanol de (-)-cis-2-(2-clorofenil)-5,7-di-hidroxi-8-[4r-(3s-hidroxi-1-metil)piperidinil]-4h-1-bezopiran-4-ona

Info

Publication number: PT1252155E
Authority: PT; Portugal
Prior art keywords: piperidinyl; chlorophenyl; dihydroxy; cis; hydroxy
Prior art date: 2000-01-18

Application number

PT01902993T

Other languages

English (en)

Inventor

Kurt M Kesseler

Original Assignee

Aventis Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-18

Filing date

2001-01-08

Publication date

2005-04-29

2001-01-08 Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc

2005-04-29 Publication of PT1252155E publication Critical patent/PT1252155E/pt

Links

LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title abstract 4
239000012453 solvate Substances 0.000 title abstract 2
-1 2-CHLOROPHENYL Chemical class 0.000 title 1
125000004182 2-chlorophenyl group Chemical group [H]C1=C([H])C(Cl)=C(*)C([H])=C1[H] 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
125000003386 piperidinyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

PT01902993T 2000-01-18 2001-01-08 Solvato de etanol de (-)-cis-2-(2-clorofenil)-5,7-di-hidroxi-8-[4r-(3s-hidroxi-1-metil)piperidinil]-4h-1-bezopiran-4-ona PT1252155E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US48781500A	2000-01-18	2000-01-18

Publications (1)

Publication Number	Publication Date
PT1252155E true PT1252155E (pt)	2005-04-29

Family

ID=23937213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT01902993T PT1252155E (pt)	2000-01-18	2001-01-08	Solvato de etanol de (-)-cis-2-(2-clorofenil)-5,7-di-hidroxi-8-[4r-(3s-hidroxi-1-metil)piperidinil]-4h-1-bezopiran-4-ona

Country Status (26)

Country	Link
EP (1)	EP1252155B1 (pt)
JP (1)	JP2003520798A (pt)
KR (1)	KR100825530B1 (pt)
CN (1)	CN1395577A (pt)
AR (1)	AR027226A1 (pt)
AT (1)	ATE284400T1 (pt)
AU (1)	AU2001230869A1 (pt)
BR (1)	BR0107724A (pt)
CA (1)	CA2397594C (pt)
CZ (1)	CZ301235B6 (pt)
DE (1)	DE60107652T2 (pt)
DK (1)	DK1252155T3 (pt)
EA (1)	EA005182B1 (pt)
ES (1)	ES2228800T3 (pt)
HU (1)	HU225155B1 (pt)
IL (2)	IL150643A0 (pt)
MX (1)	MXPA02006965A (pt)
NO (1)	NO322626B1 (pt)
NZ (1)	NZ520281A (pt)
PL (1)	PL201690B1 (pt)
PT (1)	PT1252155E (pt)
SI (1)	SI1252155T1 (pt)
SK (1)	SK287216B6 (pt)
TW (1)	TWI293072B (pt)
WO (1)	WO2001053294A1 (pt)
ZA (1)	ZA200205640B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR112019003722A2 (pt)	2016-08-23	2019-05-28	Eisai R&D Man Co Ltd	terapias de combinação para o tratamento de carcinoma hepatocelular
WO2018170447A1 (en)	2017-03-16	2018-09-20	Eisai R&D Management Co., Ltd.	Combination therapies for the treatment of breast cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN164232B (pt) *	1986-04-11	1989-02-04	Hoechst India
US5284856A (en) *	1988-10-28	1994-02-08	Hoechst Aktiengesellschaft	Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
DE3836676A1 (de) *	1988-10-28	1990-05-03	Hoechst Ag	Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel
US5908934A (en) *	1996-09-26	1999-06-01	Bristol-Myers Squibb Company	Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

2001
- 2001-01-08 IL IL15064301A patent/IL150643A0/xx unknown
- 2001-01-08 AU AU2001230869A patent/AU2001230869A1/en not_active Abandoned
- 2001-01-08 DE DE60107652T patent/DE60107652T2/de not_active Expired - Lifetime
- 2001-01-08 PT PT01902993T patent/PT1252155E/pt unknown
- 2001-01-08 MX MXPA02006965A patent/MXPA02006965A/es active IP Right Grant
- 2001-01-08 KR KR1020027009140A patent/KR100825530B1/ko not_active Expired - Fee Related
- 2001-01-08 NZ NZ520281A patent/NZ520281A/en not_active IP Right Cessation
- 2001-01-08 DK DK01902993T patent/DK1252155T3/da active
- 2001-01-08 WO PCT/US2001/000520 patent/WO2001053294A1/en not_active Ceased
- 2001-01-08 ES ES01902993T patent/ES2228800T3/es not_active Expired - Lifetime
- 2001-01-08 EP EP01902993A patent/EP1252155B1/en not_active Expired - Lifetime
- 2001-01-08 HU HU0204297A patent/HU225155B1/hu not_active IP Right Cessation
- 2001-01-08 AT AT01902993T patent/ATE284400T1/de active
- 2001-01-08 BR BR0107724-4A patent/BR0107724A/pt not_active Application Discontinuation
- 2001-01-08 EA EA200200776A patent/EA005182B1/ru not_active IP Right Cessation
- 2001-01-08 PL PL355992A patent/PL201690B1/pl not_active IP Right Cessation
- 2001-01-08 JP JP2001553768A patent/JP2003520798A/ja active Pending
- 2001-01-08 CA CA2397594A patent/CA2397594C/en not_active Expired - Fee Related
- 2001-01-08 CN CN01803857A patent/CN1395577A/zh active Pending
- 2001-01-08 SK SK1037-2002A patent/SK287216B6/sk not_active IP Right Cessation
- 2001-01-08 CZ CZ20022467A patent/CZ301235B6/cs not_active IP Right Cessation
- 2001-01-08 SI SI200130293T patent/SI1252155T1/xx unknown
- 2001-01-17 TW TW090101052A patent/TWI293072B/zh not_active IP Right Cessation
- 2001-01-17 AR ARP010100186A patent/AR027226A1/es not_active Application Discontinuation
2002
- 2002-07-08 IL IL150643A patent/IL150643A/en not_active IP Right Cessation
- 2002-07-12 NO NO20023385A patent/NO322626B1/no not_active IP Right Cessation
- 2002-07-15 ZA ZA200205640A patent/ZA200205640B/en unknown

Also Published As

Publication number	Publication date
HUP0204297A2 (hu)	2003-04-28
PL201690B1 (pl)	2009-04-30
CZ20022467A3 (cs)	2002-10-16
ATE284400T1 (de)	2004-12-15
DE60107652D1 (de)	2005-01-13
ZA200205640B (en)	2003-11-26
IL150643A0 (en)	2003-02-12
CA2397594C (en)	2010-03-23
NO20023385L (no)	2002-08-27
TWI293072B (en)	2008-02-01
IL150643A (en)	2009-08-03
MXPA02006965A (es)	2004-09-06
HU225155B1 (en)	2006-07-28
EP1252155B1 (en)	2004-12-08
EP1252155A1 (en)	2002-10-30
ES2228800T3 (es)	2005-04-16
HUP0204297A3 (en)	2005-04-28
CN1395577A (zh)	2003-02-05
NZ520281A (en)	2004-04-30
JP2003520798A (ja)	2003-07-08
AR027226A1 (es)	2003-03-19
WO2001053294A1 (en)	2001-07-26
SI1252155T1 (en)	2005-06-30
NO322626B1 (no)	2006-11-06
CZ301235B6 (cs)	2009-12-16
EA005182B1 (ru)	2004-12-30
PL355992A1 (en)	2004-05-31
AU2001230869A1 (en)	2001-07-31
KR20020069514A (ko)	2002-09-04
DE60107652T2 (de)	2005-12-22
EA200200776A1 (ru)	2002-12-26
CA2397594A1 (en)	2001-07-26
KR100825530B1 (ko)	2008-04-25
SK287216B6 (sk)	2010-03-08
DK1252155T3 (da)	2005-04-04
NO20023385D0 (no)	2002-07-12
BR0107724A (pt)	2002-10-01
SK10372002A3 (sk)	2002-12-03

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AU2001276048A1 (en)	2002-01-14	Rapid-melt semi-solid compositions, methods of making same and methods of using same
AU2001279284A1 (en)	2002-01-14	Rapid-melt semi-solid compositions, methods of making same and methods of using same
AU2002210409A1 (en)	2002-05-21	Ethanol process
AU2002213336A1 (en)	2002-04-29	Substituted heterocyclic compounds for treating multidrug resistance
AU2001259961A1 (en)	2001-11-20	Method and technology for high-throughput lead profiling
AU2002211652A1 (en)	2002-04-22	Method of making an electrode
NO20024893D0 (no)	2002-10-10	Fremgangsmåter for ansamitocin-produksjon
AU2001261631A1 (en)	2001-11-26	Answering natural language queries
ID22456A (id)	1999-10-21	Proses pembuatan diester-diester 2,3,5-trimetilhidrokuinon
AU2002239739A1 (en)	2002-06-03	Compositions, methods and kits relating to remodelin
ES2175899T3 (es)	2002-11-16	Procedimiento para la preparacion de derivados de piridindicarboxilato.
PL355992A1 (en)	2004-05-31	Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one
NO20023386D0 (no)	2002-07-12	Pseudopolymorf av (-)-cis-2-(2-klorfenyl)-5,7-dihydroksy-8(4R- (3S-hydroksy-1-metyl)piperidinyl)-4H-1-benzopyran-4-on
AUPQ825300A0 (en)	2000-07-13	Method of sentence analysis
DE69813576D1 (de)	2003-05-22	Ethanolherstellung durch mutanthefe
AU2002343178A1 (en)	2003-06-17	Method to query an embebbed database
PL347056A1 (en)	2001-10-22	Novel compounds of heterocycloalkylbezocyclobutane and heterocycloarylbenzocyclobutane, method of obtaining them and pharmacological compositions containming such compounds
ITRM20000347A0 (it)	2000-06-26	Metodo di rappresentazione numerica.
AU2001223955A1 (en)	2002-06-24	Method for searching internet domain names
ATE244214T1 (de)	2003-07-15	Phosphat-vermittelte cyclisierung
AU2001284421A1 (en)	2002-03-22	Method of determining base sequence
AUPQ723500A0 (en)	2000-05-25	An analysis method
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