PT2247291T - Métodos e composições para tratamento de doença inflamatória do intestino - Google Patents

Métodos e composições para tratamento de doença inflamatória do intestino

Info

Publication number
PT2247291T
PT2247291T PT09708397T PT09708397T PT2247291T PT 2247291 T PT2247291 T PT 2247291T PT 09708397 T PT09708397 T PT 09708397T PT 09708397 T PT09708397 T PT 09708397T PT 2247291 T PT2247291 T PT 2247291T
Authority
PT
Portugal
Prior art keywords
compositions
methods
inflammatory bowel
bowel disease
treating inflammatory
Prior art date
Application number
PT09708397T
Other languages
English (en)
Inventor
Julius Borody Thomas
Gosselin Patrick
Original Assignee
Red Hill Biopharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Red Hill Biopharma Ltd filed Critical Red Hill Biopharma Ltd
Publication of PT2247291T publication Critical patent/PT2247291T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT09708397T 2008-02-08 2009-02-05 Métodos e composições para tratamento de doença inflamatória do intestino PT2247291T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6514408P 2008-02-08 2008-02-08

Publications (1)

Publication Number Publication Date
PT2247291T true PT2247291T (pt) 2019-02-01

Family

ID=40951740

Family Applications (1)

Application Number Title Priority Date Filing Date
PT09708397T PT2247291T (pt) 2008-02-08 2009-02-05 Métodos e composições para tratamento de doença inflamatória do intestino

Country Status (18)

Country Link
US (10) US8343511B2 (pt)
EP (2) EP2247291B1 (pt)
JP (1) JP5572872B2 (pt)
AU (1) AU2009212097B2 (pt)
CA (1) CA2714043C (pt)
CY (1) CY1121465T1 (pt)
DK (1) DK2247291T3 (pt)
ES (1) ES2708087T3 (pt)
HR (1) HRP20190045T1 (pt)
HU (1) HUE041305T2 (pt)
IL (1) IL207420A (pt)
NZ (1) NZ587250A (pt)
PL (1) PL2247291T3 (pt)
PT (1) PT2247291T (pt)
SI (1) SI2247291T1 (pt)
TR (1) TR201819940T4 (pt)
WO (1) WO2009097651A1 (pt)
ZA (1) ZA201005735B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2714043C (en) 2008-02-08 2016-11-08 Giaconda Limited Methods and compositions for treating inflammatory bowel disease
TWI573590B (zh) 2011-09-20 2017-03-11 雷希爾生藥有限公司 治療自體免疫疾病之組成物及方法
MX370688B (es) 2012-08-30 2019-12-19 Texas A & M Univ Sys Composiciones y métodos para sensibilización con fármaco o inhibición de una célula de cáncer.
WO2015123392A1 (en) * 2014-02-14 2015-08-20 The Texas A&M University System Compositions and methods for inhibition of angiogenesis and lymphangiogenesis
EP3145510B8 (en) * 2014-05-22 2021-10-27 Kuenstner, John, Todd Treatment of diseases using combination of ultraviolet blood irradiation and antibiotics
WO2016178240A1 (en) * 2015-05-04 2016-11-10 Gufic Biosciences Limited A freeze dried pharmaceutical formulation of rifabutin and process for preparation thereof
AU2016336133B2 (en) 2015-10-06 2021-02-25 Redhill Biopharma Ltd. Combination therapies for treating cancer
CN107202848B (zh) * 2017-07-24 2022-11-15 浙江华海药业股份有限公司 一种氯法齐明的液相色谱分析方法
CA3074257A1 (en) * 2017-08-29 2019-03-07 Weightrx Inc. System and method of automated tracking of consumable products
EP4420673A3 (en) * 2019-09-12 2024-11-06 Bioversys AG Rifabutin treatment methods, uses, and compositions
CA3187031A1 (en) * 2020-06-30 2022-01-06 Redhill Biopharma Ltd. Triple antibiotic fixed-dose combination products, dosing regimen, methods, and kits for treating pulmonary non-tuberculosis mycobacterial infections
WO2022204375A1 (en) * 2021-03-25 2022-09-29 The Regents Of The University Of Michigan Compositions and methods for detecting, preventing, and treating disturbed microbiota-immune homeostasis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840733A (en) 1996-07-01 1998-11-24 Redcell, Canada, Inc. Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes
SI0971735T1 (sl) 1997-04-01 2008-08-31 Borody Thomas J Postopek in sestavina za zdravljenje bolezni vnetja debelega äśrevesa
US6761903B2 (en) * 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
CA2714043C (en) 2008-02-08 2016-11-08 Giaconda Limited Methods and compositions for treating inflammatory bowel disease

Also Published As

Publication number Publication date
EP2247291A4 (en) 2011-04-13
AU2009212097B2 (en) 2013-06-13
US10765691B2 (en) 2020-09-08
EP2247291A1 (en) 2010-11-10
PL2247291T3 (pl) 2019-05-31
EP3391882A1 (en) 2018-10-24
US11090326B2 (en) 2021-08-17
US10105379B2 (en) 2018-10-23
US20110059136A1 (en) 2011-03-10
TR201819940T4 (tr) 2019-01-21
US20200206253A1 (en) 2020-07-02
JP5572872B2 (ja) 2014-08-20
US20140243279A1 (en) 2014-08-28
HUE041305T2 (hu) 2019-05-28
US9072763B2 (en) 2015-07-07
CY1121465T1 (el) 2020-05-29
US20180125872A1 (en) 2018-05-10
US20160228464A1 (en) 2016-08-11
AU2009212097A1 (en) 2009-08-13
US10434114B2 (en) 2019-10-08
JP2011511012A (ja) 2011-04-07
US20130237488A1 (en) 2013-09-12
SI2247291T1 (sl) 2019-03-29
US20170232028A1 (en) 2017-08-17
US20140315841A1 (en) 2014-10-23
HRP20190045T1 (hr) 2019-03-08
EP2247291B1 (en) 2018-12-05
IL207420A (en) 2015-09-24
ZA201005735B (en) 2011-10-26
CA2714043C (en) 2016-11-08
CA2714043A1 (en) 2009-08-13
ES2708087T3 (es) 2019-04-08
US20190060343A1 (en) 2019-02-28
US20200030352A1 (en) 2020-01-30
US8343511B2 (en) 2013-01-01
US9314477B2 (en) 2016-04-19
US9198926B2 (en) 2015-12-01
IL207420A0 (en) 2010-12-30
DK2247291T3 (en) 2019-01-21
WO2009097651A1 (en) 2009-08-13
NZ587250A (en) 2011-12-22
US10143702B2 (en) 2018-12-04

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