PT2265729E - Amplificação e sequenciação alvo com iniciadores compreendendo unidades de monómeros que formam triplexes - Google Patents

Amplificação e sequenciação alvo com iniciadores compreendendo unidades de monómeros que formam triplexes Download PDF

Info

Publication number: PT2265729E
Authority: PT; Portugal
Prior art keywords: oligonucleotides; forming monomer; triplex forming; primers; sequencing
Prior art date: 2008-03-10

Application number

PT97194070T

Other languages

English (en)

Inventor

Gorm Lisby

Original Assignee

Quantibact As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-03-10

Filing date

2009-03-10

Publication date

2013-10-10

2009-03-10 Application filed by Quantibact As filed Critical Quantibact As

2013-10-10 Publication of PT2265729E publication Critical patent/PT2265729E/pt

Links

239000000178 monomer Substances 0.000 title abstract 3
230000003321 amplification Effects 0.000 title 1
238000003199 nucleic acid amplification method Methods 0.000 title 1
238000012163 sequencing technique Methods 0.000 title 1
108091034117 Oligonucleotide Proteins 0.000 abstract 6
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 4
230000002255 enzymatic effect Effects 0.000 abstract 1
230000002349 favourable effect Effects 0.000 abstract 1
238000010348 incorporation Methods 0.000 abstract 1
230000008018 melting Effects 0.000 abstract 1
238000002844 melting Methods 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Microbiology (AREA)
Immunology (AREA)
Analytical Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

PT97194070T 2008-03-10 2009-03-10 Amplificação e sequenciação alvo com iniciadores compreendendo unidades de monómeros que formam triplexes PT2265729E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DKPA200800366		2008-03-10

Publications (1)

Publication Number	Publication Date
PT2265729E true PT2265729E (pt)	2013-10-10

Family

ID=40886885

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97194070T PT2265729E (pt)	2008-03-10	2009-03-10	Amplificação e sequenciação alvo com iniciadores compreendendo unidades de monómeros que formam triplexes

Country Status (13)

Country	Link
US (1)	US8501441B2 (pt)
EP (1)	EP2265729B1 (pt)
JP (1)	JP5285090B2 (pt)
KR (1)	KR101289164B1 (pt)
CN (1)	CN102016076A (pt)
AU (1)	AU2009225119B2 (pt)
BR (1)	BRPI0909063A2 (pt)
CA (1)	CA2717994C (pt)
DK (1)	DK2265729T3 (pt)
ES (1)	ES2434542T3 (pt)
NZ (1)	NZ588041A (pt)
PT (1)	PT2265729E (pt)
WO (1)	WO2009112032A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2285820A1 (en) *	2008-05-07	2011-02-23	Syddansk Universitet	Intercalating triplexes and duplexes using aryl naphthoimidazol and process for the preparation thereof
CN102933720B (zh) *	2010-05-07	2015-03-18	昆特拜克股份公司	用于生成具有单链悬突的双链核酸的方法
EP2691524A1 (en) *	2011-03-28	2014-02-05	Quantibact A/S	Stacking nucleic acid and methods for use thereof
EP2798088B1 (en)	2011-12-27	2018-06-06	Region Syddanmark	Detection of adenomas of the colon or rectum
KR101589483B1 (ko) *	2014-02-21	2016-01-28	디엑스진주식회사	핵산과 신호 프로브의 비대칭 등온증폭을 이용한 핵산의 검출방법
EP3201628B1 (en) *	2014-10-02	2020-11-18	Ventana Medical Systems, Inc.	Polymers and conjugates comprising the same
GB2582561B (en) *	2019-03-22	2023-05-24	Ev Offshore Ltd	Downhole imaging

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2409980B1 (en) *	2005-04-14	2015-06-03	Applied Biosystems, LLC	3'modified oligonucleotides containing pseudoisocytosine nucleobase derivatives and applications thereof as primers or probes
AU2006251496B2 (en) *	2005-05-25	2012-11-22	Tina Holding Aps	Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) and process for the preparation of TINA

2009
- 2009-03-10 JP JP2010550029A patent/JP5285090B2/ja not_active Expired - Fee Related
- 2009-03-10 EP EP09719407.0A patent/EP2265729B1/en active Active
- 2009-03-10 US US12/921,561 patent/US8501441B2/en not_active Expired - Fee Related
- 2009-03-10 DK DK09719407.0T patent/DK2265729T3/da active
- 2009-03-10 KR KR1020107022708A patent/KR101289164B1/ko not_active Expired - Fee Related
- 2009-03-10 NZ NZ588041A patent/NZ588041A/xx not_active IP Right Cessation
- 2009-03-10 AU AU2009225119A patent/AU2009225119B2/en not_active Ceased
- 2009-03-10 CA CA2717994A patent/CA2717994C/en not_active Expired - Fee Related
- 2009-03-10 BR BRPI0909063-0A patent/BRPI0909063A2/pt not_active IP Right Cessation
- 2009-03-10 CN CN2009801167150A patent/CN102016076A/zh active Pending
- 2009-03-10 PT PT97194070T patent/PT2265729E/pt unknown
- 2009-03-10 ES ES09719407T patent/ES2434542T3/es active Active
- 2009-03-10 WO PCT/DK2009/050051 patent/WO2009112032A1/en not_active Ceased

Also Published As

Publication number	Publication date
AU2009225119B2 (en)	2012-11-15
EP2265729A1 (en)	2010-12-29
CA2717994A1 (en)	2009-09-17
EP2265729B1 (en)	2013-07-03
KR101289164B1 (ko)	2013-07-31
AU2009225119A1 (en)	2009-09-17
US20110076728A1 (en)	2011-03-31
WO2009112032A1 (en)	2009-09-17
JP5285090B2 (ja)	2013-09-11
NZ588041A (en)	2013-01-25
CA2717994C (en)	2014-09-16
DK2265729T3 (da)	2013-10-14
ES2434542T3 (es)	2013-12-16
JP2011512850A (ja)	2011-04-28
BRPI0909063A2 (pt)	2015-08-25
US8501441B2 (en)	2013-08-06
CN102016076A (zh)	2011-04-13
KR20100123904A (ko)	2010-11-25

Publication	Publication Date	Title
PT2265729E (pt)	2013-10-10	Amplificação e sequenciação alvo com iniciadores compreendendo unidades de monómeros que formam triplexes
PE20190843A1 (es)	2019-06-17	Arn de direccion a adn generico
WO2007139723A8 (en)	2009-12-17	Chemicallymodified oligonucleotide primers for nucleic acid amplification
MX2010004984A (es)	2010-07-29	Uso de oligonucleotidos con bases modificadas en hibridacion de acidos nucleicos.
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WO2009135093A3 (en)	2010-04-15	Rnase-h-based assays utilizing modified rna monomers
MX346956B (es)	2017-04-06	Captura directa, amplificación y secuenciación de objetivo adn usando cebadores inmovilizados.
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WO2008084405A3 (en)	2009-01-29	Circular chromosome conformation capture (4c)
WO2008118212A3 (en)	2009-01-15	In vivo delivery of double stranded rna to a target cell
WO2007004057A3 (en)	2007-05-18	Chromosome conformation capture-on-chip (4c) assay
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RU2015150098A (ru)	2017-05-29	Способ амплификации днк на основе внедрения в цепь
JP2016540517A5 (pt)	2018-02-01
ATE540110T1 (de)	2012-01-15	Oligonukleotid-leiterkonstruktion und system zur erzeugung von molekularer vielfalt
WO2006125447A3 (en)	2007-01-11	Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (tina) and process for the preparation of tina
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