PT2376480T - Derivados de sulfonamida como agentes indutores de apoptose seletivos de bcl-2 para o tratamento do cancro e de doenças imunes - Google Patents

Derivados de sulfonamida como agentes indutores de apoptose seletivos de bcl-2 para o tratamento do cancro e de doenças imunes

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Publication number
PT2376480T
PT2376480T PT97956064T PT09795606T PT2376480T PT 2376480 T PT2376480 T PT 2376480T PT 97956064 T PT97956064 T PT 97956064T PT 09795606 T PT09795606 T PT 09795606T PT 2376480 T PT2376480 T PT 2376480T
Authority
PT
Portugal
Prior art keywords
bcl
cancer
treatment
immune diseases
inducing agents
Prior art date
Application number
PT97956064T
Other languages
English (en)
Inventor
J Mcclellan William
A Mantei Robert
T Wang Gary
Bruncko Milan
R Kunzer Aaron
D Wendt Michael
A Doherty George
W Elmore Steven
Hasvold Lisa
Hexamer Laura
H Park Chang
Park Cheol-Min
M Petros Andrew
Song Xiaohong
J Souers Andrew
M Sullivan Gerard
Tao Zhi-Fu
Wang Le
Ding Hong
Wang Xilu
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41786218&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2376480(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of PT2376480T publication Critical patent/PT2376480T/pt

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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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