PT2450035T - Combinação de adapaleno e peróxido de benzoilo para o tratamento de lesões inflamatórias do acne - Google Patents

Combinação de adapaleno e peróxido de benzoilo para o tratamento de lesões inflamatórias do acne

Info

Publication number
PT2450035T
PT2450035T PT12152317T PT12152317T PT2450035T PT 2450035 T PT2450035 T PT 2450035T PT 12152317 T PT12152317 T PT 12152317T PT 12152317 T PT12152317 T PT 12152317T PT 2450035 T PT2450035 T PT 2450035T
Authority
PT
Portugal
Prior art keywords
adapalene
treatment
benzoyl peroxide
inflammatory acne
peroxide combination
Prior art date
Application number
PT12152317T
Other languages
English (en)
Inventor
Gross Denis
Loesche Christian
Poncet Michel
Abou-Chacra Vernet Marie-Line
Original Assignee
Galderma Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37763873&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2450035(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Publication of PT2450035T publication Critical patent/PT2450035T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PT12152317T 2006-07-13 2007-07-12 Combinação de adapaleno e peróxido de benzoilo para o tratamento de lesões inflamatórias do acne PT2450035T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0652968A FR2903603B1 (fr) 2006-07-13 2006-07-13 Combinaison d'adapalene et de peroxyde de benzole dans le traitement de l'acne
US83349106P 2006-07-27 2006-07-27

Publications (1)

Publication Number Publication Date
PT2450035T true PT2450035T (pt) 2019-02-26

Family

ID=37763873

Family Applications (2)

Application Number Title Priority Date Filing Date
PT12152317T PT2450035T (pt) 2006-07-13 2007-07-12 Combinação de adapaleno e peróxido de benzoilo para o tratamento de lesões inflamatórias do acne
PT77874782T PT2046318E (pt) 2006-07-13 2007-07-12 Combinação de adapaleno e peróxido de benzoilo para o tratamento de lesões inflamatórias do acne

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT77874782T PT2046318E (pt) 2006-07-13 2007-07-12 Combinação de adapaleno e peróxido de benzoilo para o tratamento de lesões inflamatórias do acne

Country Status (23)

Country Link
US (6) US8129362B2 (pt)
EP (2) EP2046318B1 (pt)
JP (3) JP2009542779A (pt)
KR (3) KR20160120352A (pt)
CN (1) CN101541320B (pt)
AR (1) AR061989A1 (pt)
AU (1) AU2007274288B2 (pt)
BR (1) BRPI0713182A8 (pt)
CA (1) CA2656456A1 (pt)
CO (1) CO6150136A2 (pt)
CY (1) CY1121398T1 (pt)
DK (2) DK2046318T3 (pt)
ES (2) ES2423951T3 (pt)
FR (1) FR2903603B1 (pt)
HU (1) HUE043502T2 (pt)
LT (1) LT2450035T (pt)
MX (1) MX2009000319A (pt)
PL (2) PL2046318T3 (pt)
PT (2) PT2450035T (pt)
RU (3) RU2009104949A (pt)
SI (2) SI2450035T1 (pt)
TR (1) TR201819658T4 (pt)
WO (1) WO2008006888A1 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820186B2 (en) 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
FR2910321B1 (fr) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr) 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
JP2011510907A (ja) * 2007-01-30 2011-04-07 ガルデルマ・リサーチ・アンド・デヴェロップメント 尋常性ざ瘡の長期間の処置のためのアダパレンおよび過酸化ベンゾイルの使用
CN101969923A (zh) * 2007-11-30 2011-02-09 盖尔德马研究及发展公司 含有至少一种萘甲酸衍生物、过氧化苯甲酰和至少一种成膜剂的组合物、它们的制备方法及其用途
WO2009138516A1 (en) * 2008-05-16 2009-11-19 Galderma Research & Development Therapy regimen for treating acne related diseases
JP2013518920A (ja) * 2010-02-09 2013-05-23 ガルデルマ・リサーチ・アンド・デヴェロップメント 非白人系人種における炎症後色素沈着の減少と共にざ瘡の処置を目的とする、アダパレンと過酸化ベンゾイルとの組合せを含む皮膚科学的組成物
CA2796412A1 (en) * 2010-04-29 2011-11-03 Galderma Research & Development Method for treating scars with adapalene 0.3%
FR2969491B1 (fr) * 2010-12-23 2013-07-12 Galderma Res & Dev Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant une combinaison d'adapalene et de bpo
US8563535B2 (en) * 2011-03-29 2013-10-22 Kamal Mehta Combination composition comprising benzoyl peroxide and adapalene
CA2870690A1 (en) * 2012-05-25 2013-11-28 Galderma Research & Development Treatment of preadolescent moderate acne vulgaris
DK2922528T3 (en) 2012-11-20 2017-09-18 Allergan Inc TOPICAL DAPSON AND DAPSON / ADAPALEN COMPOSITIONS AND PROCEDURES FOR USE THEREOF
BR112016022743A2 (pt) * 2014-04-01 2017-08-15 Galderma Res & Dev Método para tratar e/ou evitar pelo menos uma cicatriz de acne, uso de uma combinação fixa de adapaleno e peróxido de benzoíla e composição
SMT202000705T1 (it) 2014-07-25 2021-01-05 Galderma Res & Dev Combinazione di adapalene e benzoilperossido per il trattamento di acne grave
WO2017029665A1 (en) * 2015-08-20 2017-02-23 Sol-Gel Technologies Ltd. Compositions for topical application comprising benzoyl peroxide and adapalene
JP6679299B2 (ja) * 2015-12-21 2020-04-15 第一三共ヘルスケア株式会社 ニキビ治療用外用医薬組成物
KR101986177B1 (ko) * 2016-10-31 2019-06-05 (주)동구바이오제약 여드름 치료용 약물의 생체이용률을 증진시키는 약학적 조성물
WO2018080284A1 (ko) * 2016-10-31 2018-05-03 (주)동구바이오제약 여드름 치료용 약물의 생체이용률을 증진시키는 약학적 조성물
MX395001B (es) * 2017-03-08 2025-03-24 Centro Int De Cosmiatria S A P I De C V Composición y método para el tratamiento tópico del acné severo.
CN110913849A (zh) * 2017-03-30 2020-03-24 科学派有限责任公司 治疗和预防感染的方法
JP2022542616A (ja) 2019-08-01 2022-10-05 ボシュ ヘルス アイルランド リミテッド 局所組成物
EP4493179A4 (en) * 2022-03-14 2026-04-22 Blue Hill Tech Llc LONG-SHELF BENZOYL PEROXIDE FORMULATIONS AND THEIR PRODUCTION PROCESSES

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW203552B (en) * 1992-02-18 1993-04-11 J Baroody Lloyd Compositions of clindamycin and benzoyl peroxide for acne treatment
FR2727609B1 (fr) 1994-12-06 1997-01-10 Oreal Ensemble de distribution pour l'application d'un produit de consistance liquide a pateuse
FR2775566B1 (fr) 1998-03-03 2000-05-12 Oreal Cupule porte raisin et ensemble de conditionnement pour un produit de maquillage la comportant
US6559189B2 (en) * 1999-04-28 2003-05-06 Regents Of The University Of Michigan Non-toxic antimicrobial compositions and methods of use
FR2806273B1 (fr) 2000-03-16 2002-10-04 Oreal Dispositif de conditionnement et d'application d'un produit cosmetique ou de soin
US7820186B2 (en) * 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
FR2833841B1 (fr) 2001-12-21 2005-07-22 Galderma Res & Dev Gel comprenant au moins un retinoide et du peroxyde de benzoyle
FR2837101B1 (fr) 2002-03-12 2004-07-02 Galderma Res & Dev Utilisation de l'acide 6-[1-adamantyl)-4-methoxyphenyl]-2- naphthoique pour le traitement de desordres dermatologiques
GB0301577D0 (en) * 2003-01-23 2003-02-26 Edko Pazarlama Tanitim Ltd Sti Topical pharmaceutical and/or cosmetic dispense systems
WO2005009458A1 (en) 2003-07-23 2005-02-03 Xoma Technology Ltd. Use of xmp-629 for the treatment of acne
US20050239723A1 (en) 2004-04-27 2005-10-27 Amin Avinash N Compositions and methods useful for treatment of acne
US20060128808A1 (en) 2004-10-20 2006-06-15 Galderma Research & Development, S.N.C. Method of using adapalene in acne maintenance therapy
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
FR2901139B1 (fr) 2006-05-17 2009-03-20 Galderma Res & Dev S N C Snc Compositions comprenant au moins un derive de l'acide naphtoique et du peroxyde de benzoyle, leurs procedes de preparation, et leurs utilisations

Also Published As

Publication number Publication date
US8071644B2 (en) 2011-12-06
FR2903603B1 (fr) 2009-03-20
CY1121398T1 (el) 2020-05-29
KR20090028764A (ko) 2009-03-19
US8129362B2 (en) 2012-03-06
CO6150136A2 (es) 2010-04-20
EP2046318A1 (en) 2009-04-15
RU2012144414A (ru) 2014-04-27
WO2008006888A1 (en) 2008-01-17
AR061989A1 (es) 2008-08-10
US20140296340A1 (en) 2014-10-02
HUE043502T2 (hu) 2019-08-28
US20080033047A1 (en) 2008-02-07
EP2046318B1 (en) 2013-06-05
EP2450035A1 (en) 2012-05-09
TR201819658T4 (tr) 2019-01-21
US20120059063A1 (en) 2012-03-08
DK2046318T3 (da) 2013-08-05
DK2450035T3 (en) 2019-02-25
MX2009000319A (es) 2009-03-12
US20090253788A1 (en) 2009-10-08
SI2450035T1 (sl) 2019-03-29
ES2703505T3 (es) 2019-03-11
KR20150003917A (ko) 2015-01-09
JP2009542779A (ja) 2009-12-03
EP2450035B1 (en) 2018-11-21
JP2016029094A (ja) 2016-03-03
CN101541320B (zh) 2014-04-09
CN101541320A (zh) 2009-09-23
FR2903603A1 (fr) 2008-01-18
ES2423951T3 (es) 2013-09-25
US20170202803A1 (en) 2017-07-20
PL2046318T3 (pl) 2013-12-31
AU2007274288A1 (en) 2008-01-17
LT2450035T (lt) 2019-01-25
US8785420B2 (en) 2014-07-22
BRPI0713182A2 (pt) 2012-04-17
RU2012136952A (ru) 2014-03-10
BRPI0713182A8 (pt) 2018-01-02
AU2007274288B2 (en) 2013-05-02
PL2450035T3 (pl) 2019-04-30
SI2046318T1 (sl) 2013-11-29
JP2014040481A (ja) 2014-03-06
CA2656456A1 (en) 2008-01-17
KR20160120352A (ko) 2016-10-17
US20120115947A1 (en) 2012-05-10
RU2009104949A (ru) 2010-08-20
PT2046318E (pt) 2013-09-04

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