PT2663864T - Método de avaliação de imunodiversidade e seu uso - Google Patents

Método de avaliação de imunodiversidade e seu uso

Info

Publication number
PT2663864T
PT2663864T PT12734581T PT12734581T PT2663864T PT 2663864 T PT2663864 T PT 2663864T PT 12734581 T PT12734581 T PT 12734581T PT 12734581 T PT12734581 T PT 12734581T PT 2663864 T PT2663864 T PT 2663864T
Authority
PT
Portugal
Prior art keywords
immunodiversity
assessment method
assessment
immunodiversity assessment
Prior art date
Application number
PT12734581T
Other languages
English (en)
Inventor
Han Jian
Original Assignee
Irepertoire Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irepertoire Inc filed Critical Irepertoire Inc
Publication of PT2663864T publication Critical patent/PT2663864T/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PT12734581T 2011-01-14 2012-01-17 Método de avaliação de imunodiversidade e seu uso PT2663864T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161432638P 2011-01-14 2011-01-14

Publications (1)

Publication Number Publication Date
PT2663864T true PT2663864T (pt) 2019-06-21

Family

ID=46491067

Family Applications (1)

Application Number Title Priority Date Filing Date
PT12734581T PT2663864T (pt) 2011-01-14 2012-01-17 Método de avaliação de imunodiversidade e seu uso

Country Status (9)

Country Link
US (1) US20120183969A1 (pt)
EP (1) EP2663864B8 (pt)
JP (1) JP2014503223A (pt)
CN (1) CN103797366A (pt)
CA (1) CA2824854A1 (pt)
DK (1) DK2663864T3 (pt)
ES (1) ES2730980T3 (pt)
PT (1) PT2663864T (pt)
WO (1) WO2012097374A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011140433A2 (en) 2010-05-07 2011-11-10 The Board Of Trustees Of The Leland Stanford Junior University Measurement and comparison of immune diversity by high-throughput sequencing
US20160002731A1 (en) * 2012-10-01 2016-01-07 Adaptive Biotechnologies Corporation Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization
US9909180B2 (en) 2013-02-04 2018-03-06 The Board Of Trustees Of The Leland Stanford Junior University Measurement and comparison of immune diversity by high-throughput sequencing
CN105164277B (zh) * 2013-02-11 2021-05-28 Cb生物技术公司 用于评估免疫组库的方法
WO2014144495A1 (en) 2013-03-15 2014-09-18 Abvitro, Inc. Single cell bar-coding for antibody discovery
JP6164759B2 (ja) 2013-11-21 2017-07-19 Repertoire Genesis株式会社 T細胞受容体およびb細胞受容体レパトアの解析システムならびにその治療および診断への利用
KR102541849B1 (ko) 2014-09-15 2023-06-09 에이비비트로, 엘엘씨 고-처리량 뉴클레오티드 라이브러리 서열결정
WO2016081919A1 (en) 2014-11-20 2016-05-26 Icahn School Of Medicine At Mount Sinai Methods for determining recombination diversity at a genomic locus
KR102801954B1 (ko) * 2015-03-06 2025-04-28 아이리퍼트와, 인크. 개체의 면역 레퍼토리에서의 변화를 측정하는 방법
GB201506806D0 (en) 2015-04-22 2015-06-03 Univ Edinburgh Rheumatoid arthritis patient stratification
CN108348166B (zh) * 2015-09-09 2022-06-03 普梭梅根公司 用于与抗生素使用相关的感染性疾病及其它健康状况的源自微生物群系的诊断及治疗方法和系统
CN106557667B (zh) * 2015-09-28 2019-03-26 深圳华大基因科技有限公司 评价疫苗免疫效果的系统
US11047011B2 (en) * 2015-09-29 2021-06-29 iRepertoire, Inc. Immunorepertoire normality assessment method and its use
JP6100867B1 (ja) * 2015-11-06 2017-03-22 振武 曽 免疫状態の分析のための検査方法
EP3585797A4 (en) * 2017-03-09 2020-12-30 Irepertoire, Inc. DIMER-AVOIDED MULTIPLEX POLYMERASE CHAIN REACTION FOR MULTI-TARGET AMPLIFICATION
WO2018209625A1 (zh) * 2017-05-18 2018-11-22 北京吉因加科技有限公司 一种基于外周血无创性检测病灶免疫组库多样性的分析系统及其用途
CN107177693B (zh) * 2017-07-19 2020-11-06 中山大学 一种多倍pcr扩增方法
CN110246539B (zh) * 2019-04-15 2020-04-28 成都益安博生物技术有限公司 一种免疫力水平评估的方法及装置
WO2020236745A1 (en) * 2019-05-17 2020-11-26 iRepertoire, Inc. Immunorepertoire wellness assessment systems and methods
CN110564858A (zh) * 2019-10-29 2019-12-13 成都益安博生物技术有限公司 一种用于预测免疫检测点调节类药物疗效的rt-pcr试剂盒及其预测方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022455A1 (fr) * 1992-04-30 1993-11-11 Taisho Pharmaceutical Co., Ltd. Procede de detection d'un gene recepteur d'antigene de lymphocytes t
EP1549764B1 (en) * 2002-10-11 2010-10-06 Erasmus Universiteit Rotterdam Nucleic acid amplification primers for pcr-based clonality studies
US20060160153A1 (en) * 2002-12-03 2006-07-20 Jean-Pierre Abastado Method to measure a t cell response and its uses to qualify antigen-presenting cells
EP2062982A1 (fr) 2007-11-26 2009-05-27 ImmunID Procédé d'étude de la diversité combinatoire V(D)J
WO2009124293A1 (en) 2008-04-03 2009-10-08 Hudson Alpha Institute For Biotechnology Amplicon rescue multiplex polymerase chain reaction for amplificaton of multiple targets
WO2009137255A2 (en) * 2008-04-16 2009-11-12 Hudsonalpha Institute For Biotechnology Method for evaluating and comparing immunorepertoires
EP2364368B1 (en) * 2008-11-07 2014-01-15 Sequenta, Inc. Methods of monitoring conditions by sequence analysis
RU2014144463A (ru) 2009-06-25 2015-06-20 Фред Хатчинсон Кансэр Рисёч Сентер Способ измерения адаптивного иммунитета
WO2011139372A1 (en) * 2010-05-06 2011-11-10 Sequenta, Inc. Sequence analysis of complex amplicons

Also Published As

Publication number Publication date
WO2012097374A1 (en) 2012-07-19
EP2663864B1 (en) 2019-04-10
ES2730980T3 (es) 2019-11-13
JP2014503223A (ja) 2014-02-13
EP2663864A4 (en) 2016-07-06
CN103797366A (zh) 2014-05-14
EP2663864B8 (en) 2019-06-05
DK2663864T3 (da) 2019-06-24
EP2663864A1 (en) 2013-11-20
US20120183969A1 (en) 2012-07-19
CA2824854A1 (en) 2012-07-19

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