PT2677029T - Métodos para o fabrico de polipéptidos processados proteoliticamente - Google Patents

Métodos para o fabrico de polipéptidos processados proteoliticamente

Info

Publication number
PT2677029T
PT2677029T PT131848640T PT13184864T PT2677029T PT 2677029 T PT2677029 T PT 2677029T PT 131848640 T PT131848640 T PT 131848640T PT 13184864 T PT13184864 T PT 13184864T PT 2677029 T PT2677029 T PT 2677029T
Authority
PT
Portugal
Prior art keywords
manufacture
methods
proteolytically processed
processed polypeptides
polypeptides
Prior art date
Application number
PT131848640T
Other languages
English (en)
Inventor
Rummel Andreas
Original Assignee
Ipsen Bioinnovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44453883&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2677029(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ipsen Bioinnovation Ltd filed Critical Ipsen Bioinnovation Ltd
Publication of PT2677029T publication Critical patent/PT2677029T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT131848640T 2011-05-19 2011-05-19 Métodos para o fabrico de polipéptidos processados proteoliticamente PT2677029T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13184864.0A EP2677029B1 (en) 2011-05-19 2011-05-19 Methods for the manufacture of proteolytically processed polypeptides
EP11004152.2A EP2524963B1 (en) 2011-05-19 2011-05-19 Methods for the manufacture of proteolytically processed polypeptides

Publications (1)

Publication Number Publication Date
PT2677029T true PT2677029T (pt) 2017-08-11

Family

ID=44453883

Family Applications (1)

Application Number Title Priority Date Filing Date
PT131848640T PT2677029T (pt) 2011-05-19 2011-05-19 Métodos para o fabrico de polipéptidos processados proteoliticamente

Country Status (6)

Country Link
EP (4) EP3162894B1 (pt)
DK (1) DK2677029T3 (pt)
ES (3) ES2634261T3 (pt)
HU (1) HUE033172T2 (pt)
PL (1) PL2677029T3 (pt)
PT (1) PT2677029T (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3162894B1 (en) 2011-05-19 2024-01-10 Ipsen Bioinnovation Limited Methods for the manufacture of proteolytically processed polypeptides
WO2014079495A1 (en) * 2012-11-21 2014-05-30 Syntaxin Limited Methods for the manufacture of proteolytically processed polypeptides
GB201407525D0 (en) * 2014-04-29 2014-06-11 Syntaxin Ltd Manufacture of recombinant clostridium botulinum neurotoxins
US11242515B2 (en) 2016-05-16 2022-02-08 President And Fellows Of Harvard College Method for purification and activation of botulinum neurotoxin
EP3263710A1 (en) 2016-07-01 2018-01-03 Ipsen Biopharm Limited Production of activated clostridial neurotoxins
KR102174197B1 (ko) 2019-06-12 2020-11-04 주식회사 앤씨비아이티 생산성이 향상된 비독성 프로테아제
GB202003813D0 (en) 2020-03-16 2020-04-29 Ipsen Biopharm Ltd Treatment of upper facial lines
BR112022018456A2 (pt) 2020-03-16 2022-11-01 Ipsen Biopharm Ltd Tratamento de espasticidade de membro
JP2024534384A (ja) 2021-09-16 2024-09-20 イプセン バイオファーム リミテッド 頸部ジストニアを治療する用途の修飾ＢｏＮＴ／Ａ
GB202113602D0 (en) 2021-09-23 2021-11-10 Ipsen Biopharm Ltd Treatment of a disorder affecting an eyelid muscle of a subject
KR20240067100A (ko) 2021-09-23 2024-05-16 입센 바이오팜 리미티드 대상체의 안검 근육에 이환된 장애의 치료에 사용하기 위한 변형된 bont/a
WO2023089343A1 (en) 2021-11-22 2023-05-25 Ipsen Biopharm Limited Treatment of pain
GB202206362D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of upper facial lines
GB202206361D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of a facial dystonia
GB202206348D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of limb spasticity
GB202206353D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of cervical dystonia
GB202213479D0 (en) 2022-09-14 2022-10-26 Ipsen Biopharm Ltd Cell-free clostridial neurotoxin assays
GB202307439D0 (en) 2023-05-18 2023-07-05 Ipsen Biopharm Ltd Treatment of a headache disorder with botylinum neurotoxin a
WO2025093845A1 (en) 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of high dose chimeric botulinum toxin a for the treatment of upper facial lines
WO2025093844A1 (en) 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm
GB202320108D0 (en) 2023-12-28 2024-02-14 Ipsen Biopharm Ltd Biosensor
GB202404021D0 (en) 2024-03-20 2024-05-01 Ipsen Biopharm Ltd Cell-based neurotoxin assay

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005222A1 (en) 1994-08-08 1996-02-22 Wisconsin Alumni Research Foundation Purification and pharmaceutical compositions containing type g botulinum neurotoxin
US8012491B2 (en) * 1996-08-23 2011-09-06 Syntaxin, Ltd. Recombinant toxin fragments
DE19856897A1 (de) 1998-12-10 2000-06-15 Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh Therapeutikum zur Unterdrückung von Schnarchgeräuschen
WO2002015700A1 (en) * 2000-08-24 2002-02-28 Coulter Pharmaceutical, Inc. Prodrugs activated by plasmin and their use in cancer chemotherapy
US9072735B2 (en) * 2005-10-03 2015-07-07 Yong Qian Proteinases destroy cancer tumor's solid structure and kill cancer cells locally
US8486422B2 (en) 2007-07-26 2013-07-16 Allergan, Inc. Methods of activating clostridial toxins
EP3162894B1 (en) 2011-05-19 2024-01-10 Ipsen Bioinnovation Limited Methods for the manufacture of proteolytically processed polypeptides

Also Published As

Publication number Publication date
EP3162894A2 (en) 2017-05-03
ES2974687T3 (es) 2024-07-01
DK2677029T3 (da) 2017-08-07
ES2708661T3 (es) 2019-04-10
ES2634261T3 (es) 2017-09-27
EP2524963B1 (en) 2018-10-31
EP2677029B1 (en) 2017-05-10
PL2677029T3 (pl) 2017-10-31
HUE033172T2 (en) 2017-11-28
EP3162894A3 (en) 2017-08-09
EP2677029A3 (en) 2014-06-11
EP2677029A2 (en) 2013-12-25
EP2524963A1 (en) 2012-11-21
EP3162894B1 (en) 2024-01-10
EP4375371A2 (en) 2024-05-29
EP4375371A3 (en) 2024-07-31

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