PT2684027T - Rápida quantificação de biomoléculas num biossensor nanofluídico seletivamente funcionalizado e seu método - Google Patents
Rápida quantificação de biomoléculas num biossensor nanofluídico seletivamente funcionalizado e seu métodoInfo
- Publication number
- PT2684027T PT2684027T PT127114494T PT12711449T PT2684027T PT 2684027 T PT2684027 T PT 2684027T PT 127114494 T PT127114494 T PT 127114494T PT 12711449 T PT12711449 T PT 12711449T PT 2684027 T PT2684027 T PT 2684027T
- Authority
- PT
- Portugal
- Prior art keywords
- biomolecules
- selectively functionalized
- rapid quantification
- nanofluidic biosensor
- biosensor
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y35/00—Methods or apparatus for measurement or analysis of nanostructures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
- G01N2021/058—Flat flow cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Composite Materials (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Optics & Photonics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2011050979 | 2011-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2684027T true PT2684027T (pt) | 2020-01-27 |
Family
ID=45922721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT127114494T PT2684027T (pt) | 2011-03-09 | 2012-02-06 | Rápida quantificação de biomoléculas num biossensor nanofluídico seletivamente funcionalizado e seu método |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9547004B2 (pt) |
| EP (1) | EP2684027B1 (pt) |
| JP (1) | JP6130306B2 (pt) |
| CN (1) | CN103502795B (pt) |
| AU (1) | AU2012226463B2 (pt) |
| BR (1) | BR112013022952B1 (pt) |
| CA (1) | CA2829178C (pt) |
| ES (1) | ES2767123T3 (pt) |
| PT (1) | PT2684027T (pt) |
| WO (1) | WO2012120387A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9194838B2 (en) | 2010-03-03 | 2015-11-24 | Osaka University | Method and device for identifying nucleotide, and method and device for determining nucleotide sequence of polynucleotide |
| WO2015007559A1 (en) * | 2013-07-17 | 2015-01-22 | Abionic Sa | Method and device for bioassays |
| EP3047282B1 (en) | 2013-09-18 | 2019-05-15 | Quantum Biosystems Inc. | Biomolecule sequencing devices, systems and methods |
| JP2015077652A (ja) | 2013-10-16 | 2015-04-23 | クオンタムバイオシステムズ株式会社 | ナノギャップ電極およびその製造方法 |
| PT3080589T (pt) * | 2013-12-13 | 2019-06-25 | Abionic Sa | Sistema de evacuação de gás para biossensor nano fluídico |
| JP6636455B2 (ja) * | 2014-01-24 | 2020-01-29 | 国立大学法人大阪大学 | 生体分子配列決定装置、システムおよび方法 |
| CN106573240B (zh) * | 2014-07-03 | 2020-05-01 | 阿比奥尼克公司 | 用于诸如全血的流体试样的快速分子定量的胶囊 |
| CN104651500B (zh) * | 2015-01-30 | 2017-06-30 | 华东理工大学 | 气单胞菌溶素纳米孔通道的制备方法及其应用 |
| KR20180101595A (ko) | 2016-02-01 | 2018-09-12 | 프리벤치오 인코포레이티드 | 심혈관 질환 및 사건을 위한 진단학적 및 예후적 방법 |
| KR20190075010A (ko) | 2016-04-27 | 2019-06-28 | 퀀텀 바이오시스템즈 가부시키가이샤 | 생체분자의 측정 및 시퀀싱을 위한 시스템 및 방법 |
| CN113324958A (zh) * | 2021-05-19 | 2021-08-31 | 江南大学 | 一种可视化检测重金属汞的快检毛细管及其制备方法和应用 |
| DE102022208445A1 (de) * | 2022-08-15 | 2024-02-15 | Carl Zeiss Microscopy Gmbh | Verbessertes FCS-Verfahren |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH182409A (de) | 1934-03-03 | 1936-02-15 | Ig Farbenindustrie Ag | Vaselinähnliches Produkt. |
| AU588245B2 (en) * | 1984-06-13 | 1989-09-14 | Inverness Medical Switzerland Gmbh | Devices for use in chemical test procedures |
| US4775637A (en) * | 1984-12-10 | 1988-10-04 | Purtec Limited | An immunoassay apparatus having at least two waveguides and method for its use |
| US5637469A (en) * | 1992-05-01 | 1997-06-10 | Trustees Of The University Of Pennsylvania | Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems |
| JP4010171B2 (ja) * | 2001-04-16 | 2007-11-21 | 東ソー株式会社 | 微小流路構造体、その製造方法及びその用途 |
| CN1690711B (zh) * | 2004-04-23 | 2010-04-14 | 中国人民解放军军事医学科学院微生物流行病研究所 | 基于上转换发光技术免疫层析试纸条 |
| FR2890173B1 (fr) * | 2005-08-23 | 2008-02-22 | Vedalab Sa | Dispositif de determination d'un analyte dans un echantillon liquide par un test sandwich et un test de competition |
| WO2009100442A2 (en) * | 2008-02-07 | 2009-08-13 | The Board Of Regents Of The University Of Texas System | Methods for detecting molecule-molecule interactions with a single detection channel |
| WO2010042007A1 (en) * | 2008-10-10 | 2010-04-15 | Jonas Tegenfeldt | Method for the mapping of the local at/gc ratio along dna |
| KR101226957B1 (ko) * | 2008-12-08 | 2013-02-07 | 한국전자통신연구원 | 일회용 진단 키트 |
| JP2012515927A (ja) | 2009-01-23 | 2012-07-12 | ドレクセル・ユニバーシティー | 炎症を検出するための量子ドットを用いた装置および方法 |
| US9810680B2 (en) | 2009-04-16 | 2017-11-07 | Nanonex Corporation | Nanogap electronic detector for measuring properties of a biomolecule stretched in a nanochannel, and method thereof |
| US8246799B2 (en) * | 2009-05-28 | 2012-08-21 | Nabsys, Inc. | Devices and methods for analyzing biomolecules and probes bound thereto |
| CA2782009C (en) * | 2009-11-27 | 2017-10-03 | Ecole Polytechnique Federale De Lausanne (Epfl) | Nanofluidic biosensor and its use for rapid measurement of biomolecular interactions in solution and methods |
-
2012
- 2012-02-06 JP JP2013557188A patent/JP6130306B2/ja active Active
- 2012-02-06 US US14/003,277 patent/US9547004B2/en active Active
- 2012-02-06 BR BR112013022952-7A patent/BR112013022952B1/pt active IP Right Grant
- 2012-02-06 CA CA2829178A patent/CA2829178C/en active Active
- 2012-02-06 ES ES12711449T patent/ES2767123T3/es active Active
- 2012-02-06 CN CN201280012408.XA patent/CN103502795B/zh active Active
- 2012-02-06 PT PT127114494T patent/PT2684027T/pt unknown
- 2012-02-06 WO PCT/IB2012/050527 patent/WO2012120387A1/en not_active Ceased
- 2012-02-06 EP EP12711449.4A patent/EP2684027B1/en active Active
- 2012-02-06 AU AU2012226463A patent/AU2012226463B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2684027A1 (en) | 2014-01-15 |
| HK1187982A1 (zh) | 2014-04-17 |
| US9547004B2 (en) | 2017-01-17 |
| BR112013022952B1 (pt) | 2020-09-08 |
| BR112013022952A2 (pt) | 2016-12-06 |
| AU2012226463A1 (en) | 2013-10-10 |
| CA2829178A1 (en) | 2012-09-13 |
| JP6130306B2 (ja) | 2017-05-17 |
| US20140256573A1 (en) | 2014-09-11 |
| JP2014507668A (ja) | 2014-03-27 |
| CN103502795B (zh) | 2016-02-24 |
| CN103502795A (zh) | 2014-01-08 |
| EP2684027B1 (en) | 2019-12-11 |
| WO2012120387A1 (en) | 2012-09-13 |
| ES2767123T3 (es) | 2020-06-16 |
| CA2829178C (en) | 2020-01-07 |
| AU2012226463B2 (en) | 2015-03-12 |
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