PT2753346T - Ceramidase e diferenciação celular - Google Patents

Ceramidase e diferenciação celular

Info

Publication number
PT2753346T
PT2753346T PT128300860T PT12830086T PT2753346T PT 2753346 T PT2753346 T PT 2753346T PT 128300860 T PT128300860 T PT 128300860T PT 12830086 T PT12830086 T PT 12830086T PT 2753346 T PT2753346 T PT 2753346T
Authority
PT
Portugal
Prior art keywords
ceramidase
cell differentiation
differentiation
cell
Prior art date
Application number
PT128300860T
Other languages
English (en)
Original Assignee
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinai School Medicine filed Critical Sinai School Medicine
Publication of PT2753346T publication Critical patent/PT2753346T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/50Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16DCOUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
    • F16D3/00Yielding couplings, i.e. with means permitting movement between the connected parts during the drive
    • F16D3/50Yielding couplings, i.e. with means permitting movement between the connected parts during the drive with the coupling parts connected by one or more intermediate members
    • F16D3/64Yielding couplings, i.e. with means permitting movement between the connected parts during the drive with the coupling parts connected by one or more intermediate members comprising elastic elements arranged between substantially-radial walls of both coupling parts
    • F16D3/68Yielding couplings, i.e. with means permitting movement between the connected parts during the drive with the coupling parts connected by one or more intermediate members comprising elastic elements arranged between substantially-radial walls of both coupling parts the elements being made of rubber or similar material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655Chondrocytes; Cartilage
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16DCOUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
    • F16D41/00Freewheels or freewheel clutches
    • F16D41/20Freewheels or freewheel clutches with expandable or contractable clamping ring or band
    • F16D41/206Freewheels or freewheel clutches with expandable or contractable clamping ring or band having axially adjacent coils, e.g. helical wrap-springs
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16FSPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
    • F16F15/00Suppression of vibrations in systems; Means or arrangements for avoiding or reducing out-of-balance forces, e.g. due to motion
    • F16F15/10Suppression of vibrations in rotating systems by making use of members moving with the system
    • F16F15/12Suppression of vibrations in rotating systems by making use of members moving with the system using elastic members or friction-damping members, e.g. between a rotating shaft and a gyratory mass mounted thereon
    • F16F15/121Suppression of vibrations in rotating systems by making use of members moving with the system using elastic members or friction-damping members, e.g. between a rotating shaft and a gyratory mass mounted thereon using springs as elastic members, e.g. metallic springs
    • F16F15/124Elastomeric springs
    • F16F15/1245Elastic elements arranged between substantially-radial walls of two parts rotatable with respect to each other, e.g. between engaging teeth
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16HGEARING
    • F16H55/00Elements with teeth or friction surfaces for conveying motion; Worms, pulleys or sheaves for gearing mechanisms
    • F16H55/32Friction members
    • F16H55/36Pulleys
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16DCOUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
    • F16D2300/00Special features for couplings or clutches
    • F16D2300/06Lubrication details not provided for in group F16D13/74
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16HGEARING
    • F16H55/00Elements with teeth or friction surfaces for conveying motion; Worms, pulleys or sheaves for gearing mechanisms
    • F16H55/32Friction members
    • F16H55/36Pulleys
    • F16H2055/366Pulleys with means providing resilience or vibration damping

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Aviation & Aerospace Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Pulleys (AREA)
PT128300860T 2011-09-07 2012-09-07 Ceramidase e diferenciação celular PT2753346T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161531937P 2011-09-07 2011-09-07

Publications (1)

Publication Number Publication Date
PT2753346T true PT2753346T (pt) 2020-05-22

Family

ID=47753575

Family Applications (1)

Application Number Title Priority Date Filing Date
PT128300860T PT2753346T (pt) 2011-09-07 2012-09-07 Ceramidase e diferenciação celular

Country Status (3)

Country Link
US (1) US20130059685A1 (pt)
HR (1) HRP20200794T8 (pt)
PT (1) PT2753346T (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11236812B2 (en) * 2012-09-10 2022-02-01 Zen S/A Industria Metalurgica Decoupler with one-way clutch and fail-safe system
JP6256013B2 (ja) * 2014-01-09 2018-01-10 株式会社ジェイテクト プーリユニット
FR3046823B1 (fr) * 2016-01-14 2019-09-27 Psa Automobiles Sa. Dispositif de transmission de mouvement et de filtrage
JP6756214B2 (ja) * 2016-09-26 2020-09-16 セイコーエプソン株式会社 ロボット、歯車装置および歯車装置の製造方法
DE102017005986A1 (de) * 2017-06-23 2018-12-27 Neumayer Tekfor Engineering Gmbh Schwingungsdämpfer für einen Antriebsstrang

Family Cites Families (37)

* Cited by examiner, † Cited by third party
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US1410544A (en) * 1918-01-08 1922-03-28 United Shoe Machinery Corp Self-lubricating pulley
US2398261A (en) * 1941-11-24 1946-04-09 Deister Concentrator Company Flexible coupling
US2873590A (en) * 1955-12-16 1959-02-17 Louis P Croset Flexible couplings, dampers, gearwheels and like devices
US2995044A (en) * 1957-09-12 1961-08-08 Tann Corp Two-step pulley
US3140128A (en) * 1961-05-10 1964-07-07 Tann Corp Self-lubricating bearing
US4328879A (en) * 1978-04-27 1982-05-11 The Gates Rubber Company Shock-absorbing sprocket, drive assembly, and the like
US4486183A (en) * 1980-06-30 1984-12-04 The Gates Rubber Company Torsionally elastic power transmitting device and drive
EP0218378B1 (en) * 1985-10-04 1991-07-31 Vickers Shipbuilding & Engineering Limited A flexible shaft-coupling device
DE3621187A1 (de) * 1986-06-25 1988-01-21 Hackforth Gmbh & Co Kg Elastische wellenkupplung
US5452622A (en) * 1993-02-09 1995-09-26 Magi, L.P. Stress dissipation gear
EP0626523B1 (de) * 1993-03-26 1996-12-11 CENTA-ANTRIEBE KIRSCHEY GmbH Zweistufige elastische Wellenkupplung
US5474499A (en) * 1993-07-12 1995-12-12 The United States Of America As Represented By The Secretary Of The Navy Flexible drive shaft coupling
GB9420741D0 (en) * 1994-10-14 1994-11-30 Litens Automotive Inc Crankshaft decoupler
FR2734034B1 (fr) * 1995-05-12 1997-07-11 Hutchinson Dispositif de decouplage, notamment poulie decoupleuse, destine a un vehicule automobile
JP3671571B2 (ja) * 1996-02-29 2005-07-13 株式会社デンソー 動力伝達装置
US5956998A (en) * 1996-06-06 1999-09-28 Fenelon; Paul J. Stress reduction gear and apparatus using same
US5797540A (en) * 1997-01-27 1998-08-25 Generac Corporation Method of making a power-transmitting coupling
JP4087499B2 (ja) * 1998-05-11 2008-05-21 Nskワーナー株式会社 ワンウェイクラッチ
JP2001343024A (ja) * 2000-03-29 2001-12-14 Toyota Industries Corp 動力伝達機構
JP2002098213A (ja) * 2000-09-22 2002-04-05 Toyota Industries Corp 動力伝達機構
US6802779B2 (en) * 2000-10-27 2004-10-12 Denso Corporation Pulley type torque transmitting apparatus
JP4590795B2 (ja) * 2000-11-22 2010-12-01 株式会社デンソー プーリユニット
DE10255913B4 (de) * 2002-11-29 2005-07-28 Timken Gmbh Vorrichtung zum Dämpfen von Drehschwingungen
US7549938B2 (en) * 2003-01-07 2009-06-23 Forbo Financial Services Ag Treadmill belt
US7093703B2 (en) * 2003-04-23 2006-08-22 Koyo Seiko Co., Ltd. One-way clutch integrated with a rolling bearing, and method of producing the same
WO2005057037A1 (en) * 2003-12-09 2005-06-23 Litens Automotive Partnership Spring travel limitor for overrunning decoupler
JP4730580B2 (ja) * 2004-04-12 2011-07-20 日立工機株式会社 電動工具及び歯車装置
FR2878305B1 (fr) * 2004-11-24 2008-05-30 Hutchinson Sa Poulie d'organe de transmission de puissance, alterno-demarreur separe equipe d'une telle poulie et systeme d'entrainement de moteur thermique
FR2891039B1 (fr) * 2005-09-19 2009-05-22 Hutchinson Sa Poulie de transmission de puissance
EP2010792B1 (en) * 2006-04-26 2015-03-25 Litens Automotive Partnership One-way isolator for high torque devices
US7967121B2 (en) * 2007-02-19 2011-06-28 Conntechnical Industries, Inc. Strut based overrunning drives
US7651173B2 (en) * 2007-07-03 2010-01-26 The Gates Corporation Wheel isolator coupling
US7891475B2 (en) * 2007-10-25 2011-02-22 The Gates Corporation Isolator decoupler
US7931538B2 (en) * 2008-07-11 2011-04-26 Harley-Davidson Motor Company Group, Inc. Torque dampening compensator for a vehicle
US20100255943A1 (en) * 2009-04-07 2010-10-07 Connard Cali Polymer spring controlled pulley assembly for rotary devices
WO2011143580A2 (en) * 2010-05-14 2011-11-17 Connard Cali Overrunning isolating decoupler pulleys
US20120172163A1 (en) * 2010-12-29 2012-07-05 Fitz Frank A Elastomeric spring pulley assembly for rotary devices

Also Published As

Publication number Publication date
US20130059685A1 (en) 2013-03-07
HRP20200794T1 (hr) 2020-10-16
HRP20200794T8 (hr) 2021-12-10

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