PT2860184T - Sal de di-hidrogenofosfato de tenofovir disoproxil - Google Patents

Sal de di-hidrogenofosfato de tenofovir disoproxil

Info

Publication number
PT2860184T
PT2860184T PT13004844T PT13004844T PT2860184T PT 2860184 T PT2860184 T PT 2860184T PT 13004844 T PT13004844 T PT 13004844T PT 13004844 T PT13004844 T PT 13004844T PT 2860184 T PT2860184 T PT 2860184T
Authority
PT
Portugal
Prior art keywords
tenofovir disoproxil
dihydrogenphosphate salt
dihydrogenphosphate
salt
disoproxil
Prior art date
Application number
PT13004844T
Other languages
English (en)
Inventor
Holan Jan
Ridvan Ludek
Zapadlo Michal
Dammer Ondrej
Beranek Josef
Kral Vladimir
Original Assignee
Zentiva Ks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentiva Ks filed Critical Zentiva Ks
Publication of PT2860184T publication Critical patent/PT2860184T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
PT13004844T 2013-10-09 2013-10-09 Sal de di-hidrogenofosfato de tenofovir disoproxil PT2860184T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13004844.0A EP2860184B1 (en) 2013-10-09 2013-10-09 Dihydrogenphosphate salt of Tenofovir disoproxil

Publications (1)

Publication Number Publication Date
PT2860184T true PT2860184T (pt) 2018-11-20

Family

ID=49354420

Family Applications (1)

Application Number Title Priority Date Filing Date
PT13004844T PT2860184T (pt) 2013-10-09 2013-10-09 Sal de di-hidrogenofosfato de tenofovir disoproxil

Country Status (10)

Country Link
EP (1) EP2860184B1 (pt)
JP (1) JP2016534047A (pt)
KR (1) KR20160067843A (pt)
CN (1) CN105612167A (pt)
BR (1) BR112016007617A2 (pt)
EA (1) EA201690622A1 (pt)
IL (1) IL244848A0 (pt)
MX (1) MX2016003757A (pt)
PT (1) PT2860184T (pt)
WO (1) WO2015051875A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160003532A (ko) * 2014-07-01 2016-01-11 한미약품 주식회사 테노포비어 디소프록실 인산염과, 비금속염 붕해제 및 비금속염 활택제를 포함하는 약학 조성물

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998004569A1 (en) 1996-07-26 1998-02-05 Gilead Sciences, Inc. Nucleotide analogs
PT915894E (pt) 1996-07-26 2003-10-31 Gilead Sciences Inc Analogos de nucleotidos
US5935946A (en) 1997-07-25 1999-08-10 Gilead Sciences, Inc. Nucleotide analog composition and synthesis method
ATE305009T1 (de) 1997-07-25 2005-10-15 Gilead Sciences Inc Nukleotid-analog zusamensetzung und synthese verfahren
WO2007013086A1 (en) 2005-07-26 2007-02-01 Hetero Drugs Limited Novel polymorphs of tenofovir disoproxil fumarate
WO2008007392A2 (en) 2006-07-12 2008-01-17 Matrix Laboratories Limited Process for the preparation of tenofovir
WO2008140302A1 (en) 2007-05-14 2008-11-20 Ultimorphix Technologies B.V. Polymorphic forms of tenofovir disoproxil fumarate
WO2008143500A1 (en) 2007-05-22 2008-11-27 Ultimorphix Technologies B.V. Tenofovir disoproxil hemi-fumaric acid co-crystal
WO2009064174A1 (en) 2007-11-14 2009-05-22 Ultimorphix Technologies B.V. Polymorphic form of tenofovir disoproxil fumarate, method for its preparation and use
EP2220098A2 (en) * 2007-12-12 2010-08-25 Ultimorphix Technologies B.v. Solid forms of tenofovir disoproxil
NZ588796A (en) * 2008-04-25 2012-07-27 Cipla Ltd Crystalline form of tenofovir disoproxil and a process for its preparation
WO2010142761A1 (en) 2009-06-10 2010-12-16 Ultimorphix Technologies B.V. The succinate of tenofovir disoproxil
CN101781334B (zh) * 2010-03-04 2012-11-28 福建广生堂药业股份有限公司 替诺福韦酯的盐化合物,其制备方法和药物应用
CN103282369A (zh) * 2011-04-08 2013-09-04 劳乐斯实验室私营有限公司 抗逆转录病毒化合物与抗氧化酸的固体形式、其制备方法以及其药物组合物
WO2013132314A1 (en) * 2012-03-05 2013-09-12 Laurus Labs Private Limited Tenofovir phosphate, processes for the preparation and pharmaceutical composition thereof

Also Published As

Publication number Publication date
MX2016003757A (es) 2016-07-08
EP2860184B1 (en) 2018-08-29
JP2016534047A (ja) 2016-11-04
KR20160067843A (ko) 2016-06-14
IL244848A0 (en) 2016-05-31
WO2015051875A1 (en) 2015-04-16
EP2860184A1 (en) 2015-04-15
CN105612167A (zh) 2016-05-25
EA201690622A1 (ru) 2016-08-31
BR112016007617A2 (pt) 2017-08-01

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