PT2905335T - Anticorpo anti-hdlk-1 tendo uma atividade anti-tumoral in vivo - Google Patents

Anticorpo anti-hdlk-1 tendo uma atividade anti-tumoral in vivo

Info

Publication number
PT2905335T
PT2905335T PT138430707T PT13843070T PT2905335T PT 2905335 T PT2905335 T PT 2905335T PT 138430707 T PT138430707 T PT 138430707T PT 13843070 T PT13843070 T PT 13843070T PT 2905335 T PT2905335 T PT 2905335T
Authority
PT
Portugal
Prior art keywords
hdlk
vivo
tumor activity
antibody taking
antibody
Prior art date
Application number
PT138430707T
Other languages
English (en)
Inventor
Tsurushita Naoya
Kumar Shankar
Nakamura Koji
Yanai Hiroyuki
Kanke Toru
Original Assignee
Chiome Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiome Bioscience Inc filed Critical Chiome Bioscience Inc
Publication of PT2905335T publication Critical patent/PT2905335T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT138430707T 2012-10-03 2013-10-03 Anticorpo anti-hdlk-1 tendo uma atividade anti-tumoral in vivo PT2905335T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261709282P 2012-10-03 2012-10-03

Publications (1)

Publication Number Publication Date
PT2905335T true PT2905335T (pt) 2018-03-12

Family

ID=50435137

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138430707T PT2905335T (pt) 2012-10-03 2013-10-03 Anticorpo anti-hdlk-1 tendo uma atividade anti-tumoral in vivo

Country Status (20)

Country Link
US (1) US9303086B2 (pt)
EP (1) EP2905335B1 (pt)
JP (1) JP6280040B2 (pt)
KR (1) KR102149565B1 (pt)
CN (1) CN104704119B (pt)
AU (1) AU2013325443B2 (pt)
CA (1) CA2886772C (pt)
CY (1) CY1120063T1 (pt)
DK (1) DK2905335T3 (pt)
ES (1) ES2665341T3 (pt)
HR (1) HRP20180685T1 (pt)
HU (1) HUE037274T2 (pt)
LT (1) LT2905335T (pt)
NO (1) NO2972360T3 (pt)
PL (1) PL2905335T3 (pt)
PT (1) PT2905335T (pt)
RS (1) RS57120B1 (pt)
SI (1) SI2905335T1 (pt)
SM (1) SMT201800210T1 (pt)
WO (1) WO2014054820A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101619862B1 (ko) * 2014-09-30 2016-05-12 주식회사 녹십자 간접효소면역측정법을 이용하는 인간 Fc 포함 단백질의 역가 측정키트 및 이를 이용한 Fc 포함 단백질의 역가 측정방법
CN110300601B (zh) 2017-02-08 2024-01-05 Adc治疗有限公司 吡咯并苯并二氮杂䓬-抗体缀合物
US11306141B2 (en) 2017-09-08 2022-04-19 Y-Biologics Inc. Antibody against human DLK1 and use thereof
AU2020255907A1 (en) * 2019-04-01 2021-10-28 Chiome Bioscience Inc. Medicament for treating cancer
US20230398227A1 (en) * 2020-10-05 2023-12-14 Chiome Bioscience Inc. Medicine for treating cancer
TW202309062A (zh) 2021-05-10 2023-03-01 日商凱依歐姆 生物科學股份有限公司 抗體組成物之純化方法
TW202405024A (zh) 2022-06-30 2024-02-01 日商凱依歐姆 生物科學股份有限公司 融合蛋白質
DE202024100742U1 (de) * 2023-01-25 2024-04-04 The Procter & Gamble Company Recycelbare Verpackungen von Absorptionsartikeln

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
GB9015198D0 (en) * 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
EP0605522B1 (en) * 1991-09-23 1999-06-23 Medical Research Council Methods for the production of humanized antibodies
WO1994013701A2 (en) 1992-12-11 1994-06-23 The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Healthand Human Services Delta-like gene expressed in neuroendocrine tumors
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
JP2001269174A (ja) 2000-03-24 2001-10-02 Kirin Brewery Co Ltd 骨髄異形成症候群(mds)の検出方法及びmdsの治療剤
US20030185815A1 (en) 2001-04-03 2003-10-02 Muralidhara Padigaru Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
US20040241170A1 (en) 2001-08-24 2004-12-02 Jensen Charlotte Harken Isolation of cells from neural cell populations using antibodies to fa1/dlk1
CN1646160A (zh) * 2002-03-13 2005-07-27 拜奥根Idec马萨诸塞公司 抗αvβ6抗体
US20050221392A1 (en) 2002-03-21 2005-10-06 Charlotte Harken Jensen Detection and isolation of cell populations from muscle using antibodies to fa1/dlk1
EP1600459A3 (en) 2002-06-28 2005-12-07 Domantis Limited Ligand
CA2500687A1 (en) 2002-10-02 2004-04-15 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
ES2382987T3 (es) 2003-11-28 2012-06-15 Kanagawa Academy Of Science And Technology Método de detección de cáncer de hígado, diagnóstico de cáncer de hígado y curación del cáncer
KR101512203B1 (ko) * 2006-11-10 2015-04-15 가부시키가이샤 리부텍쿠 in vivo 에서 항종양 활성을 갖는 항인간 Dlk-1 항체
WO2009116670A1 (ja) 2008-03-17 2009-09-24 株式会社リブテック in vivoで抗腫瘍活性を有する抗ヒトDlk-1抗体
MX2012009809A (es) * 2010-02-23 2012-11-23 Sanofi Sa Anticuerpos anti - integrina alfa2 y sus usos.
SMT201900074T1 (it) * 2010-05-04 2019-02-28 Five Prime Therapeutics Inc Anticorpi che legano csf1r

Also Published As

Publication number Publication date
US9303086B2 (en) 2016-04-05
DK2905335T3 (en) 2018-03-12
CA2886772A1 (en) 2014-04-10
CA2886772C (en) 2021-01-12
KR20150060761A (ko) 2015-06-03
SI2905335T1 (en) 2018-04-30
JP6280040B2 (ja) 2018-02-14
AU2013325443B2 (en) 2019-01-31
NO2972360T3 (pt) 2018-08-04
CY1120063T1 (el) 2018-12-12
EP2905335A4 (en) 2016-05-18
CN104704119B (zh) 2017-09-05
SMT201800210T1 (it) 2018-05-02
AU2013325443A1 (en) 2015-04-09
JPWO2014054820A1 (ja) 2016-08-25
CN104704119A (zh) 2015-06-10
EP2905335B1 (en) 2018-01-31
RS57120B1 (sr) 2018-06-29
US20140193432A1 (en) 2014-07-10
ES2665341T3 (es) 2018-04-25
HUE037274T2 (hu) 2018-08-28
EP2905335A1 (en) 2015-08-12
PL2905335T3 (pl) 2018-06-29
KR102149565B1 (ko) 2020-08-28
LT2905335T (lt) 2018-04-10
WO2014054820A1 (ja) 2014-04-10
HRP20180685T1 (hr) 2018-06-01

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