PT2916829T - Utilização de material baseado em óxido de silício para a libertação modificada de agentes biologicamente ativos - Google Patents

Utilização de material baseado em óxido de silício para a libertação modificada de agentes biologicamente ativos

Info

Publication number
PT2916829T
PT2916829T PT13776968T PT13776968T PT2916829T PT 2916829 T PT2916829 T PT 2916829T PT 13776968 T PT13776968 T PT 13776968T PT 13776968 T PT13776968 T PT 13776968T PT 2916829 T PT2916829 T PT 2916829T
Authority
PT
Portugal
Prior art keywords
silicon oxide
biologically active
active agents
based material
modified release
Prior art date
Application number
PT13776968T
Other languages
English (en)
Inventor
Cabrera Karin
Lang Ulrich
Peters Benjamin
Saal Christoph
Schulz Michael
Lubda Dieter
Kucera Shawn
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PT2916829T publication Critical patent/PT2916829T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Silicon Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT13776968T 2012-11-12 2013-10-14 Utilização de material baseado em óxido de silício para a libertação modificada de agentes biologicamente ativos PT2916829T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12007668 2012-11-12

Publications (1)

Publication Number Publication Date
PT2916829T true PT2916829T (pt) 2019-06-04

Family

ID=47189686

Family Applications (1)

Application Number Title Priority Date Filing Date
PT13776968T PT2916829T (pt) 2012-11-12 2013-10-14 Utilização de material baseado em óxido de silício para a libertação modificada de agentes biologicamente ativos

Country Status (9)

Country Link
US (1) US20150283090A1 (pt)
EP (1) EP2916829B1 (pt)
JP (2) JP6324396B2 (pt)
CN (1) CN104768537A (pt)
AU (1) AU2013343906B2 (pt)
CA (1) CA2890887A1 (pt)
ES (1) ES2728252T3 (pt)
PT (1) PT2916829T (pt)
WO (1) WO2014072015A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1222165A1 (zh) * 2013-11-26 2017-06-23 默克专利股份有限公司 用於生产无机颗粒材料的方法
EP3175865B1 (en) * 2014-08-01 2026-04-15 Smart Inovation Lda Functional particles, process to obtain them, and their applications
TWI628413B (zh) * 2016-10-11 2018-07-01 國立中山大學 矽電極兆赫波全波段之液晶相位調變器
WO2020127281A1 (en) 2018-12-20 2020-06-25 Merck Patent Gmbh A release system comprising a bioactive agent and a particulate material
TWI812835B (zh) * 2019-01-30 2023-08-21 德商夸茲沃克公司 結晶二氧化矽之隔離
JP2023505142A (ja) * 2019-12-02 2023-02-08 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 活性医薬成分のナノ懸濁液の担体上の堆積
JP2025135063A (ja) * 2024-03-05 2025-09-18 太陽化学株式会社 多孔質シリカ、及びその製造方法
CN118415991B (zh) * 2024-05-14 2025-01-28 上海同仁药业股份有限公司 一种氟苯尼考高分散可溶性粉剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3985170B2 (ja) * 1996-12-26 2007-10-03 直弘 曽我 無機系多孔質体の製造方法
US6207098B1 (en) * 1996-12-26 2001-03-27 Merck Patent Gmbh Method for producing porous inorganic materials
JP3962613B2 (ja) * 2001-12-27 2007-08-22 三菱化学株式会社 徐放性担体及び徐放剤
US8273371B2 (en) * 2003-06-27 2012-09-25 Johan Adriaan Martens Crystalline mesoporous oxide based materials useful for the fixation and controlled release of drugs
JP2005307120A (ja) * 2004-04-26 2005-11-04 Mitsubishi Chemicals Corp 徐放剤及びそれを用いた徐放材
EP2110414A1 (de) * 2008-04-18 2009-10-21 Nanoresins AG Oberflächenmodifizierte Siliziumdioxid-Partikel
TWI383808B (zh) * 2009-11-23 2013-02-01 國立清華大學 磷脂質包覆中孔洞二氧化矽奈米球的合成與其生醫應用
EP2571491A2 (en) * 2010-05-21 2013-03-27 President and Fellows of Harvard College Foams, including microcellular foams, containing colloidal particulates
WO2012051341A1 (en) * 2010-10-13 2012-04-19 Regents Of The University Of Minnesota Hydrothermal process for enhanced stability of mesoporous nanoparticles
DK2707329T3 (en) * 2011-05-13 2018-01-15 Merck Patent Gmbh PROCEDURE FOR MANUFACTURING INORGANIC PARTICULATE MATERIAL

Also Published As

Publication number Publication date
WO2014072015A1 (en) 2014-05-15
US20150283090A1 (en) 2015-10-08
JP2018090621A (ja) 2018-06-14
AU2013343906B2 (en) 2018-03-01
AU2013343906A1 (en) 2015-07-02
JP6557745B2 (ja) 2019-08-07
JP2016505517A (ja) 2016-02-25
EP2916829B1 (en) 2019-02-27
ES2728252T3 (es) 2019-10-23
CA2890887A1 (en) 2014-05-15
EP2916829A1 (en) 2015-09-16
CN104768537A (zh) 2015-07-08
JP6324396B2 (ja) 2018-05-16

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