PT3115367T - Composto intermediário para preparar rosuvastatina cálcica e método para preparar rosuvastatina cálcica a partir deste - Google Patents

Composto intermediário para preparar rosuvastatina cálcica e método para preparar rosuvastatina cálcica a partir deste

Info

Publication number
PT3115367T
PT3115367T PT148850589T PT14885058T PT3115367T PT 3115367 T PT3115367 T PT 3115367T PT 148850589 T PT148850589 T PT 148850589T PT 14885058 T PT14885058 T PT 14885058T PT 3115367 T PT3115367 T PT 3115367T
Authority
PT
Portugal
Prior art keywords
rosuvastatin calcium
preparing rosuvastatin
intermediate compound
therefrom
preparing
Prior art date
Application number
PT148850589T
Other languages
English (en)
Inventor
Hong Hao
Gage James
Li Jiuyuan
Shen Litao
Zhang Lei
Dong Changming
Original Assignee
Asymchem Laboratories Fuxin Co Ltd
Asymchem Lab Tianjin Co Ltd
Tianjin Asymchem Pharmaceutical Co Ltd
Asymchem Life Science Tianjin Co Ltd
Jilin Asymchem Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asymchem Laboratories Fuxin Co Ltd, Asymchem Lab Tianjin Co Ltd, Tianjin Asymchem Pharmaceutical Co Ltd, Asymchem Life Science Tianjin Co Ltd, Jilin Asymchem Laboratories Co Ltd filed Critical Asymchem Laboratories Fuxin Co Ltd
Publication of PT3115367T publication Critical patent/PT3115367T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/6512Six-membered rings having the nitrogen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT148850589T 2014-03-07 2014-03-07 Composto intermediário para preparar rosuvastatina cálcica e método para preparar rosuvastatina cálcica a partir deste PT3115367T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14885058.9A EP3115367B1 (en) 2014-03-07 2014-03-07 Intermediate compound for preparing rosuvastatin calcium and method for preparing rosuvastatin calcium therefrom
PCT/CN2014/073079 WO2015131405A1 (zh) 2014-03-07 2014-03-07 用于制备瑞舒伐他汀钙的中间体化合物以及由其制备瑞舒伐他汀钙的方法

Publications (1)

Publication Number Publication Date
PT3115367T true PT3115367T (pt) 2018-01-04

Family

ID=54054408

Family Applications (1)

Application Number Title Priority Date Filing Date
PT148850589T PT3115367T (pt) 2014-03-07 2014-03-07 Composto intermediário para preparar rosuvastatina cálcica e método para preparar rosuvastatina cálcica a partir deste

Country Status (7)

Country Link
US (1) US9926283B2 (pt)
EP (1) EP3115367B1 (pt)
JP (1) JP6240346B2 (pt)
ES (1) ES2655062T3 (pt)
HU (1) HUE037976T2 (pt)
PT (1) PT3115367T (pt)
WO (1) WO2015131405A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106674281B (zh) * 2016-12-31 2019-05-07 安徽美诺华药物化学有限公司 一种瑞舒伐他汀中间体化合物、制备方法及其用途
WO2019008593A1 (en) * 2017-07-05 2019-01-10 Melody Healthcare Pvt. Ltd PROCESS FOR THE PRODUCTION OF AMORPHOUS CALCIUM ROSUVASTATIN
CN111548312A (zh) * 2020-06-01 2020-08-18 雅本化学股份有限公司 一种瑞舒伐他汀钙片及其制备工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2648897B2 (ja) 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
GB9903472D0 (en) * 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
WO2004103977A2 (en) * 2003-05-21 2004-12-02 Ciba Specialty Chemicals Holding Inc. Process for the preparation of pyrimidine derivatives
WO2005054207A1 (en) 2003-12-04 2005-06-16 Glenmark Pharmaceuticals Limited Process for the preparation of pyrimidine derivatives
CN102351901A (zh) * 2011-08-15 2012-02-15 上海皓元化学科技有限公司 25-羟基维生素d2系列药物侧链及其制备方法
CN102643302A (zh) * 2012-04-06 2012-08-22 上海皓元化学科技有限公司 25-羟基维生素D2和1α,25-二羟基维生素D2合成中间体的制备方法
CN103804414B (zh) * 2014-03-07 2016-04-13 凯莱英医药集团(天津)股份有限公司 用于制备瑞舒伐他汀钙的中间体化合物以及由其制备瑞舒伐他汀钙的方法

Also Published As

Publication number Publication date
WO2015131405A1 (zh) 2015-09-11
EP3115367B1 (en) 2017-11-01
JP6240346B2 (ja) 2017-11-29
ES2655062T3 (es) 2018-02-16
EP3115367A1 (en) 2017-01-11
HUE037976T2 (hu) 2018-09-28
US9926283B2 (en) 2018-03-27
US20170022169A1 (en) 2017-01-26
JP2017508790A (ja) 2017-03-30
EP3115367A4 (en) 2017-01-11

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