PT3116880T - Macrociclos de ácido piridin-3-il acético como inibidores da replicação do vírus da imunodeficiência humana - Google Patents
Macrociclos de ácido piridin-3-il acético como inibidores da replicação do vírus da imunodeficiência humanaInfo
- Publication number
- PT3116880T PT3116880T PT157289505T PT15728950T PT3116880T PT 3116880 T PT3116880 T PT 3116880T PT 157289505 T PT157289505 T PT 157289505T PT 15728950 T PT15728950 T PT 15728950T PT 3116880 T PT3116880 T PT 3116880T
- Authority
- PT
- Portugal
- Prior art keywords
- macrocycles
- pyridin
- inhibitors
- acetic acid
- immunodeficiency virus
- Prior art date
Links
- 241000725303 Human immunodeficiency virus Species 0.000 title 1
- -1 Pyridin-3-yl acetic acid macrocycles Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000029812 viral genome replication Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461942244P | 2014-02-20 | 2014-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3116880T true PT3116880T (pt) | 2018-05-10 |
Family
ID=53396542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT157289505T PT3116880T (pt) | 2014-02-20 | 2015-02-19 | Macrociclos de ácido piridin-3-il acético como inibidores da replicação do vírus da imunodeficiência humana |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9637501B2 (pt) |
| EP (1) | EP3116880B1 (pt) |
| ES (1) | ES2670010T3 (pt) |
| PT (1) | PT3116880T (pt) |
| WO (1) | WO2015127003A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9409922B2 (en) | 2014-02-18 | 2016-08-09 | Bristol-Myers Squibb Company | Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication |
| BR112018002403A2 (pt) * | 2015-08-07 | 2018-09-18 | Viiv Healthcare Uk No 5 Ltd | composto, e, composição útil e método para tratar infecção de hiv |
| AR105653A1 (es) | 2015-08-11 | 2017-10-25 | VIIV HEALTHCARE UK (Nº 5) LTD | Derivados del ácido 5-(n-bencil-tetrahidroisoquinolin-6-il)-piridin-3-il acético como inhibidores de la replicación del virus de la inmunodeficiencia humana |
| TW201720798A (zh) | 2015-09-17 | 2017-06-16 | Ｖｉｉｖ醫療保健英國有限公司 | 苯并氮呯衍生物 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006125178A2 (en) | 2005-05-19 | 2006-11-23 | Xenon Pharmaceuticals Inc. | Tricyclic pyridazine compounds and their uses as therapeutic agents |
| US7939545B2 (en) | 2006-05-16 | 2011-05-10 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
| CA2705318C (en) | 2007-11-15 | 2013-12-31 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
| AU2008323561B2 (en) | 2007-11-15 | 2013-07-18 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| JP5269087B2 (ja) | 2007-11-16 | 2013-08-21 | ギリアード サイエンシス インコーポレーテッド | ヒト免疫不全ウイルス複製のインヒビター |
| MX2010005334A (es) | 2007-11-16 | 2010-05-27 | Boehringer Ingelheim Int | Inhibidores de la replicacion del virus de la inmunodeficiencia humana. |
| GB0908394D0 (en) | 2009-05-15 | 2009-06-24 | Univ Leuven Kath | Novel viral replication inhibitors |
| US8338441B2 (en) | 2009-05-15 | 2012-12-25 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| GB0913636D0 (en) | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
| SG10201408512RA (en) | 2009-12-23 | 2015-02-27 | Univ Leuven Kath | Novel antiviral compounds |
| US8629276B2 (en) | 2012-02-15 | 2014-01-14 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| WO2014021867A1 (en) | 2012-07-31 | 2014-02-06 | Hewlett-Packard Development Company, L.P. | Modify executable bits of system management memory page table |
| US8906929B2 (en) | 2012-08-16 | 2014-12-09 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| JP2016516692A (ja) | 2013-03-13 | 2016-06-09 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | ヒト免疫不全ウイルス複製の阻害剤 |
| US9193720B2 (en) * | 2014-02-20 | 2015-11-24 | Bristol-Myers Squibb Company | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
-
2015
- 2015-02-19 PT PT157289505T patent/PT3116880T/pt unknown
- 2015-02-19 US US15/119,488 patent/US9637501B2/en not_active Expired - Fee Related
- 2015-02-19 ES ES15728950.5T patent/ES2670010T3/es active Active
- 2015-02-19 EP EP15728950.5A patent/EP3116880B1/en active Active
- 2015-02-19 WO PCT/US2015/016493 patent/WO2015127003A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US9637501B2 (en) | 2017-05-02 |
| EP3116880B1 (en) | 2018-03-21 |
| ES2670010T3 (es) | 2018-05-29 |
| US20170008908A1 (en) | 2017-01-12 |
| WO2015127003A1 (en) | 2015-08-27 |
| EP3116880A1 (en) | 2017-01-18 |
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