PT3136030T - Método de liofilização. - Google Patents

Método de liofilização.

Info

Publication number
PT3136030T
PT3136030T PT161763941T PT16176394T PT3136030T PT 3136030 T PT3136030 T PT 3136030T PT 161763941 T PT161763941 T PT 161763941T PT 16176394 T PT16176394 T PT 16176394T PT 3136030 T PT3136030 T PT 3136030T
Authority
PT
Portugal
Prior art keywords
lyophilization method
lyophilization
Prior art date
Application number
PT161763941T
Other languages
English (en)
Inventor
Hall Gasteyer Theodore
Rex Sever Robert
Hunek Balazs
Grinter Nigel
Lee Verdone Melinda
Original Assignee
Sp Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sp Ind Inc filed Critical Sp Ind Inc
Publication of PT3136030T publication Critical patent/PT3136030T/pt

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT161763941T 2006-02-10 2007-02-07 Método de liofilização. PT3136030T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77186806P 2006-02-10 2006-02-10
US11/702,479 US8793895B2 (en) 2006-02-10 2007-02-05 Lyophilization system and method

Publications (1)

Publication Number Publication Date
PT3136030T true PT3136030T (pt) 2019-10-25

Family

ID=38366837

Family Applications (2)

Application Number Title Priority Date Filing Date
PT77501492T PT1982132T (pt) 2006-02-10 2007-02-07 Método de liofilização
PT161763941T PT3136030T (pt) 2006-02-10 2007-02-07 Método de liofilização.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT77501492T PT1982132T (pt) 2006-02-10 2007-02-07 Método de liofilização

Country Status (15)

Country Link
US (3) US8793895B2 (pt)
EP (3) EP3567328A1 (pt)
JP (1) JP5090374B2 (pt)
KR (1) KR101265381B1 (pt)
AU (1) AU2007215418B2 (pt)
BR (2) BR122019027321B1 (pt)
CA (1) CA2640590C (pt)
DK (2) DK1982132T3 (pt)
ES (2) ES2602501T3 (pt)
HU (2) HUE031810T2 (pt)
IL (1) IL192544A (pt)
NO (1) NO20083548L (pt)
PT (2) PT1982132T (pt)
SI (2) SI3136030T1 (pt)
WO (1) WO2007095033A2 (pt)

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US8015841B2 (en) 2006-09-08 2011-09-13 Praxair Technology, Inc. Cryogenic refrigeration system for lyophilization
US8240065B2 (en) * 2007-02-05 2012-08-14 Praxair Technology, Inc. Freeze-dryer and method of controlling the same
WO2010028488A1 (en) * 2008-09-12 2010-03-18 Enwave Corporation Apparatus and method for dehydrating biological materials with freezing and microwaving
US20110179667A1 (en) * 2009-09-17 2011-07-28 Lee Ron C Freeze drying system
US8689460B2 (en) * 2010-09-28 2014-04-08 Baxter International Inc. Optimization of nucleation and crystallization for lyophilization using gap freezing
US8966782B2 (en) * 2010-09-28 2015-03-03 Baxter International Inc. Optimization of nucleation and crystallization for lyophilization using gap freezing
US8549768B2 (en) * 2011-03-11 2013-10-08 Linde Aktiengesellschaft Methods for freeze drying
US20140047851A1 (en) * 2011-03-28 2014-02-20 Praxair Technology, Inc. Bulk freezing of biopharmaceuticals
US8839528B2 (en) * 2011-04-29 2014-09-23 Millrock Technology, Inc. Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice fog distribution
JP2013055230A (ja) * 2011-09-05 2013-03-21 Toshiba Corp 半導体基板の超臨界乾燥方法
FR2990269B1 (fr) * 2012-05-02 2018-06-29 L'air Liquide,Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Procede de lyophilisation
JP5827178B2 (ja) * 2012-06-05 2015-12-02 北越紀州製紙株式会社 セルロース多孔質体及びその製造方法
US8875413B2 (en) * 2012-08-13 2014-11-04 Millrock Technology, Inc. Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost
DE102012021655B4 (de) 2012-11-03 2023-03-30 Hof Sonderanlagenbau Gmbh Verfahren zur Gefriertrocknung eines mit einem Lösungsmittel versehenen, feuchten Produktes
EP2970878B1 (en) 2013-03-15 2018-05-23 Truckee Applied Genomics, LLC Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue
CN105452791B (zh) * 2013-05-29 2017-05-31 基伊埃工程技术股份有限公司 提供内联灭菌冷冻干燥容纳在手推车托盘中产品的方法、用于执行该方法的系统和对该方法的使用
US9121637B2 (en) * 2013-06-25 2015-09-01 Millrock Technology Inc. Using surface heat flux measurement to monitor and control a freeze drying process
US20160228371A1 (en) * 2013-10-18 2016-08-11 Abbvie Inc. Stable solid units and methods of making the same
US10801070B2 (en) 2013-11-25 2020-10-13 The Broad Institute, Inc. Compositions and methods for diagnosing, evaluating and treating cancer
US11725237B2 (en) 2013-12-05 2023-08-15 The Broad Institute Inc. Polymorphic gene typing and somatic change detection using sequencing data
JP6740127B2 (ja) * 2013-12-06 2020-08-12 ザ・ブロード・インスティテュート・インコーポレイテッド 新生物ワクチン用製剤
NZ721908A (en) 2013-12-20 2022-12-23 Massachusetts Gen Hospital Combination therapy with neoantigen vaccine
CN120329449A (zh) 2014-07-17 2025-07-18 恺兴生命科技(上海)有限公司 靶向cld18a2的t淋巴细胞及其制备方法和应用
US10975442B2 (en) 2014-12-19 2021-04-13 Massachusetts Institute Of Technology Molecular biomarkers for cancer immunotherapy
EP4636401A2 (en) 2014-12-19 2025-10-22 The Broad Institute, Inc. Methods for profiling the t-cell-receptor repertoire
JP5847919B1 (ja) * 2014-12-26 2016-01-27 共和真空技術株式会社 凍結乾燥装置の凍結乾燥方法
KR102427458B1 (ko) 2015-05-19 2022-08-01 메디칸(주) 동결건조 방법 및 장치
CA2986235A1 (en) 2015-05-20 2016-11-24 The Broad Institute, Inc. Shared neoantigens
US10605527B2 (en) 2015-09-22 2020-03-31 Millrock Technology, Inc. Apparatus and method for developing freeze drying protocols using small batches of product
JP6665063B2 (ja) * 2015-11-24 2020-03-13 株式会社西部技研 乾燥装置
EP3438637B1 (en) 2016-09-08 2023-11-01 Atonarp Inc. System having pre-separation unit
US10113797B2 (en) 2016-09-09 2018-10-30 Sp Industries, Inc. Energy recovery in a freeze-drying system
CA3037544C (en) 2016-10-05 2021-10-12 Zoetis Services Llc Lyophilization methods that provide stably dehydrated protozoans for use as potent live vaccines
US11549149B2 (en) 2017-01-24 2023-01-10 The Broad Institute, Inc. Compositions and methods for detecting a mutant variant of a polynucleotide
MX421254B (es) * 2017-07-11 2025-02-10 Universal Stabilization Tech Inc Método para la conservación de material biológico.
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KR20210013013A (ko) 2018-03-09 2021-02-03 카르스젠 테라퓨틱스 리미티드 종양 치료 방법 및 조성물
EP3775740B1 (en) * 2018-04-10 2025-07-30 IMA Life North America Inc. Freeze drying process and equipment health monitoring
KR20210024549A (ko) 2018-06-29 2021-03-05 우니베르지타이트 겐트 제품 용량 단위의 동결, 건조 및/또는 동결 건조
WO2020064815A1 (en) 2018-09-26 2020-04-02 Medac Gesellschaft für klinische Spezialpräparate mbH Crystalline form of treosulfan
EP3856151B1 (en) * 2018-09-26 2023-08-23 medac Gesellschaft für klinische Spezialpräparate mbH Lyophilisate of treosulfan
US11744257B1 (en) 2018-10-19 2023-09-05 Harvest Right, LLC Freeze-drying methods including vacuum freezing
US10921058B2 (en) * 2019-01-27 2021-02-16 Vinamit Usa Llc Fully automatic convection current vacuum freeze drying method
US10676797B1 (en) * 2019-01-27 2020-06-09 Vinamit Usa Llc Concentrated sugarcane juice powder and method for preparing the same using the convection current freeze drying apparatus
US10966439B2 (en) * 2019-01-27 2021-04-06 Vinamit Usa Llc Concentrated fruit juice powder and method for preparing the same using a non-linear screw press juicer and convection current freeze drying apparatus
JP6667884B1 (ja) * 2019-07-17 2020-03-18 株式会社松井製作所 粉粒体材料の乾燥装置及び粉粒体材料の乾燥方法
CN111346253B (zh) * 2020-03-10 2022-04-08 西安培华学院 一种水溶性多层生物材料的制备方法
US11287185B1 (en) 2020-09-09 2022-03-29 Stay Fresh Technology, LLC Freeze drying with constant-pressure and constant-temperature phases
WO2022175999A1 (ja) * 2021-02-16 2022-08-25 株式会社アルバック 凍結乾燥装置、および凍結乾燥方法
US12085337B2 (en) * 2021-10-20 2024-09-10 DSM Sales & Manufacturing, Inc. Freeze-drying systems and methods
CA3249393A1 (en) 2022-01-24 2023-07-27 Ofd Biopharma, Llc METHODS, SYSTEMS AND MATERIALS FOR MANUFACTURED UNIT DOSAGE FORMS
WO2024226752A1 (en) * 2023-04-26 2024-10-31 Eli Lilly And Company Apparatuses for and methods of concentrating biomolecules
US12225914B1 (en) 2023-05-08 2025-02-18 Harvest Right, LLC Freeze dryers and drying processes for materials with low water content
WO2025157968A1 (de) 2024-01-25 2025-07-31 Iq-Mobil Gmbh Steuerung oder regelung eines gefriertrockners auf grundlage einer erfassung eines charakteristischen temperaturanstiegs in bezug auf wenigstens eine stichproben-vial einer mehrzahl von einem gefriertrocknungsprozess unterworfenen vials

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JPH05277302A (ja) * 1992-04-02 1993-10-26 Japan Steel Works Ltd:The 高水分材料の凍結濃縮方法及び装置
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Also Published As

Publication number Publication date
SI1982132T1 (sl) 2017-01-31
IL192544A0 (en) 2009-02-11
EP3136030B1 (en) 2019-09-18
BRPI0706768A2 (pt) 2011-04-05
NO20083548L (no) 2008-10-31
DK1982132T3 (en) 2016-12-05
HUE047058T2 (hu) 2020-04-28
KR20080106509A (ko) 2008-12-08
US20140325868A1 (en) 2014-11-06
ES2602501T3 (es) 2017-02-21
EP1982132A2 (en) 2008-10-22
US9651305B2 (en) 2017-05-16
DK3136030T3 (da) 2019-10-14
PT1982132T (pt) 2016-11-16
EP3567328A1 (en) 2019-11-13
IL192544A (en) 2012-07-31
BR122019027321B1 (pt) 2021-03-23
CA2640590C (en) 2013-08-06
KR101265381B1 (ko) 2013-05-20
AU2007215418A1 (en) 2007-08-23
WO2007095033A2 (en) 2007-08-23
HUE031810T2 (en) 2017-08-28
WO2007095033A3 (en) 2007-11-22
ES2748911T3 (es) 2020-03-18
US8793895B2 (en) 2014-08-05
EP3136030A1 (en) 2017-03-01
JP2009526199A (ja) 2009-07-16
SI3136030T1 (sl) 2020-02-28
BRPI0706768B1 (pt) 2020-11-17
EP1982132B1 (en) 2016-08-10
AU2007215418B2 (en) 2011-02-10
CA2640590A1 (en) 2007-08-23
US20070186437A1 (en) 2007-08-16
JP5090374B2 (ja) 2012-12-05
US20160169579A1 (en) 2016-06-16
US9200836B2 (en) 2015-12-01

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