PT3148961T - Método para preparar um sal do ácido acetilsalicílico e um aminoácido básico - Google Patents
Método para preparar um sal do ácido acetilsalicílico e um aminoácido básicoInfo
- Publication number
- PT3148961T PT3148961T PT15724710T PT15724710T PT3148961T PT 3148961 T PT3148961 T PT 3148961T PT 15724710 T PT15724710 T PT 15724710T PT 15724710 T PT15724710 T PT 15724710T PT 3148961 T PT3148961 T PT 3148961T
- Authority
- PT
- Portugal
- Prior art keywords
- salt
- preparing
- basic amino
- amino acid
- acid
- Prior art date
Links
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title 1
- 229960001138 acetylsalicylic acid Drugs 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/12—Acetic acid esters
- C07C69/14—Acetic acid esters of monohydroxylic compounds
- C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
- C07C69/157—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1454830A FR3021654B1 (fr) | 2014-05-28 | 2014-05-28 | Procede de preparation d'un sel d'acide acetylsalicylique et d'un acide amine basique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3148961T true PT3148961T (pt) | 2018-11-05 |
Family
ID=51570555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT15724710T PT3148961T (pt) | 2014-05-28 | 2015-05-28 | Método para preparar um sal do ácido acetilsalicílico e um aminoácido básico |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9745246B2 (pt) |
| EP (1) | EP3148961B1 (pt) |
| ES (1) | ES2690066T3 (pt) |
| FR (1) | FR3021654B1 (pt) |
| PT (1) | PT3148961T (pt) |
| WO (1) | WO2015181304A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106674036B (zh) * | 2016-12-22 | 2018-08-14 | 河南中医学院 | 非有机溶剂法合成赖氨匹林的方法 |
| RU2764573C2 (ru) | 2016-12-23 | 2022-01-18 | АспиЭйр ГмбХ | Улучшенный синтез частиц ацетилсалицилата лизина ⋅ глицина |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10034802A1 (de) * | 2000-07-18 | 2002-01-31 | Bayer Ag | Stabile Salze von O-Acetylsalicylsäure mit basischen Aminosäuren |
| FR2965261B1 (fr) * | 2009-09-30 | 2012-10-26 | Holis Technologies | Procede de preparation d'un sel d'acide o-acetylsalicylique d'un acide amine basique et composition obtenue par ce procede |
| FR2950625B1 (fr) * | 2009-09-30 | 2016-12-02 | Holis Tech | Procede de preparation d'un sel d'acide o-acetylsalicylique d'un acide amine basique et composition obtenue |
| FR2973370B1 (fr) * | 2011-03-29 | 2013-05-03 | Holis Technologies | Procede a faible cout pour la preparation d'un acide o-acetylsalicyclique et d'un acide amine basique |
| CN102503845A (zh) * | 2011-09-28 | 2012-06-20 | 广州普星药业有限公司 | 一种dl-赖氨酸阿司匹林盐的制备方法及其应用 |
| ITMI20121144A1 (it) * | 2012-06-28 | 2013-12-29 | Dipharma Francis Srl | Procedimento per la preparazione di un sale di un farmaco antinfiammatorio non steroideo |
-
2014
- 2014-05-28 FR FR1454830A patent/FR3021654B1/fr not_active Expired - Fee Related
-
2015
- 2015-05-28 PT PT15724710T patent/PT3148961T/pt unknown
- 2015-05-28 EP EP15724710.7A patent/EP3148961B1/fr not_active Not-in-force
- 2015-05-28 US US15/312,262 patent/US9745246B2/en not_active Expired - Fee Related
- 2015-05-28 WO PCT/EP2015/061864 patent/WO2015181304A1/fr not_active Ceased
- 2015-05-28 ES ES15724710.7T patent/ES2690066T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2690066T3 (es) | 2018-11-19 |
| US9745246B2 (en) | 2017-08-29 |
| US20170081270A1 (en) | 2017-03-23 |
| EP3148961B1 (fr) | 2018-08-22 |
| FR3021654B1 (fr) | 2016-06-24 |
| FR3021654A1 (fr) | 2015-12-04 |
| EP3148961A1 (fr) | 2017-04-05 |
| WO2015181304A1 (fr) | 2015-12-03 |
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