PT3312181T - Composto de imidazodiazepina - Google Patents

Composto de imidazodiazepina

Info

Publication number
PT3312181T
PT3312181T PT168117422T PT16811742T PT3312181T PT 3312181 T PT3312181 T PT 3312181T PT 168117422 T PT168117422 T PT 168117422T PT 16811742 T PT16811742 T PT 16811742T PT 3312181 T PT3312181 T PT 3312181T
Authority
PT
Portugal
Prior art keywords
imidazodiazepine
compound
imidazodiazepine compound
Prior art date
Application number
PT168117422T
Other languages
English (en)
Inventor
Kawakami Shimpei
Imaizumi Tomoyoshi
Masuda Naoyuki
Kunikawa Shigeki
Morita Masataka
Yarimizu Junko
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of PT3312181T publication Critical patent/PT3312181T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT168117422T 2015-06-19 2016-06-17 Composto de imidazodiazepina PT3312181T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015123478 2015-06-19

Publications (1)

Publication Number Publication Date
PT3312181T true PT3312181T (pt) 2019-10-29

Family

ID=57546103

Family Applications (1)

Application Number Title Priority Date Filing Date
PT168117422T PT3312181T (pt) 2015-06-19 2016-06-17 Composto de imidazodiazepina

Country Status (29)

Country Link
US (1) US10426784B2 (pt)
EP (1) EP3312181B1 (pt)
JP (1) JP6658753B2 (pt)
KR (1) KR102591169B1 (pt)
CN (2) CN111205292B (pt)
AR (1) AR105025A1 (pt)
AU (1) AU2016279518B2 (pt)
CA (1) CA2989982C (pt)
CO (1) CO2018000431A2 (pt)
CY (1) CY1122232T1 (pt)
DK (1) DK3312181T3 (pt)
ES (1) ES2751913T3 (pt)
HR (1) HRP20191961T1 (pt)
HU (1) HUE047430T2 (pt)
IL (1) IL256252B (pt)
LT (1) LT3312181T (pt)
MX (1) MX2017016690A (pt)
MY (1) MY197499A (pt)
PH (1) PH12017502253B1 (pt)
PL (1) PL3312181T3 (pt)
PT (1) PT3312181T (pt)
RS (1) RS59497B1 (pt)
RU (1) RU2712968C2 (pt)
SG (1) SG11201710345VA (pt)
SI (1) SI3312181T1 (pt)
TW (1) TWI697496B (pt)
UA (1) UA120006C2 (pt)
WO (1) WO2016204268A1 (pt)
ZA (1) ZA201708566B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
TWI725408B (zh) 2018-04-20 2021-04-21 美商美國禮來大藥廠 多巴胺d1受體正向異位調節劑

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1395257A1 (en) * 2001-06-12 2004-03-10 Elan Pharmaceuticals, Inc. Macrocycles useful in the treatment of alzheimer's disease
JP3813152B2 (ja) 2002-03-12 2006-08-23 メルク エンド カムパニー インコーポレーテッド 置換アミド類
WO2004000837A1 (ja) * 2002-06-25 2003-12-31 Sumitomo Pharmaceuticals Co., Ltd. 新規なベンズオキサゾリノン誘導体
JP4989976B2 (ja) * 2004-02-13 2012-08-01 プレジデント アンド フェロウズ オブ ハーバード カレッジ 翻訳開始阻害剤としての3−3−二置換オキシインドール
CN1922141A (zh) 2004-02-23 2007-02-28 大日本住友制药株式会社 新的杂环化合物
JP4914346B2 (ja) * 2004-05-27 2012-04-11 ユセベ ファルマ ソシエテ アノニム ベンズオキサゾロン誘導体、その調製方法及びその使用
CL2007002097A1 (es) 2006-07-20 2008-01-18 Smithkline Beecham Corp Compuestos derivados de pirrolidina o morfolina antagonistas de urotensina ii; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar insuficiencia cardiaca congestiva, insuficiencia cardiaca isquemica, angina, isquemia del miocardio, vejiga hiperactiva, asma y/o copd, entre otras.
PE20081229A1 (es) * 2006-12-01 2008-08-28 Merck & Co Inc Antagonistas de receptor de orexina de diazepam sustituido
WO2011163355A1 (en) * 2010-06-24 2011-12-29 Takeda Pharmaceutical Company Limited Fused heterocyclic compounds as phosphodiesterases (pdes) inhibitors
AR095883A1 (es) 2013-04-18 2015-11-18 Astellas Pharma Inc Compuestos de acetamida heterocíclica

Also Published As

Publication number Publication date
IL256252B (en) 2021-01-31
RU2712968C2 (ru) 2020-02-03
CO2018000431A2 (es) 2018-04-10
CA2989982C (en) 2023-08-15
SI3312181T1 (sl) 2020-02-28
US10426784B2 (en) 2019-10-01
RU2018101861A3 (pt) 2019-08-06
RU2018101861A (ru) 2019-07-19
HUE047430T2 (hu) 2020-04-28
EP3312181A4 (en) 2018-11-21
HRP20191961T1 (hr) 2020-02-07
LT3312181T (lt) 2019-10-10
IL256252A (en) 2018-02-28
CY1122232T1 (el) 2020-11-25
AU2016279518B2 (en) 2020-01-16
ES2751913T3 (es) 2020-04-02
DK3312181T3 (da) 2019-10-28
CA2989982A1 (en) 2016-12-22
CN111205292A (zh) 2020-05-29
RS59497B1 (sr) 2019-12-31
KR20180014732A (ko) 2018-02-09
RU2020103225A3 (pt) 2022-02-18
RU2020103225A (ru) 2020-02-04
AR105025A1 (es) 2017-08-30
PL3312181T3 (pl) 2020-01-31
JP6658753B2 (ja) 2020-03-04
EP3312181B1 (en) 2019-08-07
CN107635996B (zh) 2020-05-26
MX2017016690A (es) 2018-03-15
PH12017502253A1 (en) 2018-05-28
TWI697496B (zh) 2020-07-01
UA120006C2 (uk) 2019-09-10
PH12017502253B1 (en) 2022-11-16
EP3312181A1 (en) 2018-04-25
US20180185383A1 (en) 2018-07-05
SG11201710345VA (en) 2018-01-30
AU2016279518A1 (en) 2018-01-04
CN111205292B (zh) 2022-06-21
JPWO2016204268A1 (ja) 2018-04-05
CN107635996A (zh) 2018-01-26
ZA201708566B (en) 2019-06-26
WO2016204268A1 (ja) 2016-12-22
KR102591169B1 (ko) 2023-10-18
TW201713662A (zh) 2017-04-16
MY197499A (en) 2023-06-19

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