PT3374509T - Oligonucleótidos para induzir a expressão paterna de ube3a - Google Patents

Oligonucleótidos para induzir a expressão paterna de ube3a

Info

Publication number: PT3374509T
Authority: PT; Portugal
Prior art keywords: oligonucleotides; paternal ube3a; ube3a expression; inducing; inducing paternal
Prior art date: 2016-09-19

Application number

PT167984400T

Other languages

English (en)

Original Assignee

H Hoffnabb La Roche Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-09-19

Filing date

2016-11-11

Publication date

2021-02-15

2016-11-11 Application filed by H Hoffnabb La Roche Ag filed Critical H Hoffnabb La Roche Ag

2021-02-15 Publication of PT3374509T publication Critical patent/PT3374509T/pt

Links

108091034117 Oligonucleotide Proteins 0.000 title 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
230000001939 inductive effect Effects 0.000 title 1
230000008775 paternal effect Effects 0.000 title 1

PT167984400T 2016-09-19 2016-11-11 Oligonucleótidos para induzir a expressão paterna de ube3a PT3374509T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP16189502		2016-09-19

Publications (1)

Publication Number	Publication Date
PT3374509T true PT3374509T (pt)	2021-02-15

Family

ID=56943436

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT167984400T PT3374509T (pt)	2016-09-19	2016-11-11	Oligonucleótidos para induzir a expressão paterna de ube3a
PT231525437T PT4220360T (pt)	2016-09-19	2016-11-11	Oligonucleótidos para induzir a expressão paterna de ube3a

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PT231525437T PT4220360T (pt)	2016-09-19	2016-11-11	Oligonucleótidos para induzir a expressão paterna de ube3a

Country Status (1)

Country	Link
PT (2)	PT3374509T (pt)

2016
- 2016-11-11 PT PT167984400T patent/PT3374509T/pt unknown
- 2016-11-11 PT PT231525437T patent/PT4220360T/pt unknown

Also Published As

Publication number	Publication date
PT4220360T (pt)	2024-09-19

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