PT3448419T - Anticorpos contra o interferão beta e sua utilização - Google Patents

Anticorpos contra o interferão beta e sua utilização

Info

Publication number
PT3448419T
PT3448419T PT177331717T PT17733171T PT3448419T PT 3448419 T PT3448419 T PT 3448419T PT 177331717 T PT177331717 T PT 177331717T PT 17733171 T PT17733171 T PT 17733171T PT 3448419 T PT3448419 T PT 3448419T
Authority
PT
Portugal
Prior art keywords
interferon beta
beta antibodies
antibodies
interferon
beta
Prior art date
Application number
PT177331717T
Other languages
English (en)
Original Assignee
Brigham & Womens Hospital Inc
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital Inc, Pfizer filed Critical Brigham & Womens Hospital Inc
Publication of PT3448419T publication Critical patent/PT3448419T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PT177331717T 2016-04-29 2017-04-28 Anticorpos contra o interferão beta e sua utilização PT3448419T (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662329327P 2016-04-29 2016-04-29
US201662339709P 2016-05-20 2016-05-20
US201762483669P 2017-04-10 2017-04-10

Publications (1)

Publication Number Publication Date
PT3448419T true PT3448419T (pt) 2023-07-26

Family

ID=59215947

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177331717T PT3448419T (pt) 2016-04-29 2017-04-28 Anticorpos contra o interferão beta e sua utilização

Country Status (29)

Country Link
US (3) US10829553B2 (pt)
EP (2) EP4273165A3 (pt)
JP (2) JP6799076B2 (pt)
KR (1) KR102527840B1 (pt)
CN (1) CN109069606B (pt)
AU (1) AU2017258492B2 (pt)
BR (1) BR112018072118A2 (pt)
CA (1) CA2965652A1 (pt)
CO (1) CO2018012497A2 (pt)
DK (1) DK3448419T5 (pt)
ES (1) ES2950288T3 (pt)
FI (1) FI3448419T3 (pt)
HR (1) HRP20230605T1 (pt)
HU (1) HUE063621T2 (pt)
IL (1) IL262244B2 (pt)
MX (1) MX394513B (pt)
MY (1) MY194084A (pt)
NZ (1) NZ747225A (pt)
PE (1) PE20190371A1 (pt)
PH (1) PH12018502275B1 (pt)
PL (1) PL3448419T3 (pt)
PT (1) PT3448419T (pt)
RU (1) RU2750454C2 (pt)
SA (1) SA518400327B1 (pt)
SG (1) SG11201809456UA (pt)
SI (1) SI3448419T1 (pt)
TW (1) TWI776808B (pt)
WO (1) WO2017189983A1 (pt)
ZA (1) ZA201806682B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2950288T3 (es) 2016-04-29 2023-10-06 Pfizer Anticuerpos interferón beta y usos de los mismos
AU2017290389B2 (en) 2016-07-01 2024-09-26 Resolve Therapeutics, Llc Optimized binuclease fusions and methods
US10947295B2 (en) 2017-08-22 2021-03-16 Sanabio, Llc Heterodimers of soluble interferon receptors and uses thereof
CN112585165B8 (zh) 2018-04-25 2025-02-14 普罗米修斯生物科学公司 优化的抗tl1a抗体
EP3917965A4 (en) * 2019-01-31 2023-03-08 Immunecent Biotechnology, Inc. NEW ANTI-IFNAR1 ANTIBODIES
CN114901311A (zh) 2019-10-24 2022-08-12 普罗米修斯生物科学公司 Tnf样配体1a（tl1a）的人源化抗体及其用途
CN114733455B (zh) * 2022-04-15 2023-02-14 北京田园奥瑞生物科技有限公司 一种利用生物改性β-环糊精纳米磁颗粒进行快速哺乳动物精子分型的方法
TW202426493A (zh) * 2022-09-22 2024-07-01 美商輝瑞大藥廠 ＩＦＮβ抗體之治療方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4754065A (en) 1984-12-18 1988-06-28 Cetus Corporation Precursor to nucleic acid probe
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US6682896B1 (en) * 1988-10-14 2004-01-27 Schering Aktiengesellschaft Peptides representing epitopic sites on r-IFN-β, antibodies thereto and uses thereof
DE68925365T2 (de) * 1988-10-14 1996-09-12 Berlex Lab PEPTIDE, DIE EPITOPE AUF R-IFN-BETA REPRÄSENTIEREN, ANTIKöRPER DAGEGEN, UND IHRE ANWENDUNG
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL108584A (en) 1994-02-07 2008-03-20 Yeda Res & Dev Cloning of interferon -alpha/beta binding protein
ZA9811070B (en) * 1997-12-08 2000-07-03 Genentech Inc Type I interferons.
DE60226641D1 (de) 2001-12-03 2008-06-26 Amgen Fremont Inc Antikörperkategorisierung auf der grundlage von bindungseigenschaften
AU2003210060B2 (en) 2002-03-22 2010-02-25 Aprogen, Inc. Humanized antibody and process for preparing same
EP2270048B1 (en) 2002-12-24 2015-11-11 Rinat Neuroscience Corp. Anti-NGF antibodies and methods using same
BR112013024717A2 (pt) * 2011-04-07 2017-08-08 Genentech Inc anticorpo isolado, ácido nucleico isolado, célula hospedeira, imunoconjugado, formulação farmacêutica, método de tratar um indivíduo que tem câncer e método de inibir proliferação celular em um indivíduo
CN102898521A (zh) * 2011-07-26 2013-01-30 上海市免疫学研究所 抗β-干扰素单克隆抗体及其应用
US10647756B2 (en) 2015-05-18 2020-05-12 Pfizer Inc. Humanized antibodies
EP3313417A4 (en) 2015-06-26 2019-06-12 Bioverativ USA Inc. METHOD FOR TREATING AUTOIMMUNE AND ALLOIMMUNE DISEASES
ES2950288T3 (es) 2016-04-29 2023-10-06 Pfizer Anticuerpos interferón beta y usos de los mismos

Also Published As

Publication number Publication date
PH12018502275A1 (en) 2019-09-09
MX2018013222A (es) 2019-04-22
DK3448419T3 (da) 2023-06-26
FI3448419T3 (fi) 2023-08-02
JP6799076B2 (ja) 2020-12-09
BR112018072118A2 (pt) 2019-03-19
AU2017258492B2 (en) 2023-12-07
KR102527840B1 (ko) 2023-05-03
AU2017258492A1 (en) 2018-10-25
JP2019516366A (ja) 2019-06-20
WO2017189983A1 (en) 2017-11-02
MX394513B (es) 2025-03-24
CO2018012497A2 (es) 2018-12-14
CN109069606B (zh) 2022-07-01
CN109069606A (zh) 2018-12-21
PH12018502275B1 (en) 2024-06-28
KR20190003625A (ko) 2019-01-09
US20170313769A1 (en) 2017-11-02
CA2965652A1 (en) 2017-10-29
HUE063621T2 (hu) 2024-01-28
US20210163588A1 (en) 2021-06-03
ES2950288T3 (es) 2023-10-06
US12448439B2 (en) 2025-10-21
JP7102489B2 (ja) 2022-07-19
SG11201809456UA (en) 2018-11-29
IL262244A (en) 2018-11-29
IL262244B1 (en) 2023-09-01
US20240174742A1 (en) 2024-05-30
US10829553B2 (en) 2020-11-10
RU2018141839A (ru) 2020-05-29
RU2750454C2 (ru) 2021-06-28
TW201739764A (zh) 2017-11-16
EP4273165A3 (en) 2023-12-20
HRP20230605T1 (hr) 2023-09-29
DK3448419T5 (da) 2024-09-09
PE20190371A1 (es) 2019-03-08
EP3448419A1 (en) 2019-03-06
NZ747225A (en) 2022-07-29
ZA201806682B (en) 2022-05-25
IL262244B2 (en) 2024-01-01
TWI776808B (zh) 2022-09-11
MY194084A (en) 2022-11-11
PL3448419T3 (pl) 2023-09-04
SA518400327B1 (ar) 2022-12-03
EP3448419B1 (en) 2023-06-07
EP4273165A2 (en) 2023-11-08
JP2021040642A (ja) 2021-03-18
SI3448419T1 (sl) 2023-10-30
US11858986B2 (en) 2024-01-02
RU2018141839A3 (pt) 2020-10-16

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