PT3852525T - Método para obter uma população enriquecida de células estaminais mesenquimais funcionais, células obtidas a partir do mesmo e composições compreendendo as mesmas - Google Patents

Método para obter uma população enriquecida de células estaminais mesenquimais funcionais, células obtidas a partir do mesmo e composições compreendendo as mesmas

Info

Publication number
PT3852525T
PT3852525T PT197829112T PT19782911T PT3852525T PT 3852525 T PT3852525 T PT 3852525T PT 197829112 T PT197829112 T PT 197829112T PT 19782911 T PT19782911 T PT 19782911T PT 3852525 T PT3852525 T PT 3852525T
Authority
PT
Portugal
Prior art keywords
compositions
obtaining
mesenchymal stem
enriched population
stem cells
Prior art date
Application number
PT197829112T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Univ Valladolid
Citospin S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Valladolid, Citospin S L filed Critical Univ Valladolid
Publication of PT3852525T publication Critical patent/PT3852525T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/125Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
PT197829112T 2018-09-20 2019-09-18 Método para obter uma população enriquecida de células estaminais mesenquimais funcionais, células obtidas a partir do mesmo e composições compreendendo as mesmas PT3852525T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18382679 2018-09-20

Publications (1)

Publication Number Publication Date
PT3852525T true PT3852525T (pt) 2023-06-02

Family

ID=63722321

Family Applications (1)

Application Number Title Priority Date Filing Date
PT197829112T PT3852525T (pt) 2018-09-20 2019-09-18 Método para obter uma população enriquecida de células estaminais mesenquimais funcionais, células obtidas a partir do mesmo e composições compreendendo as mesmas

Country Status (15)

Country Link
US (2) US11930808B2 (fr)
EP (1) EP3852525B1 (fr)
JP (1) JP7401865B2 (fr)
KR (1) KR102506822B1 (fr)
CN (1) CN112770628B (fr)
AU (1) AU2019341538B2 (fr)
BR (1) BR112021005257B1 (fr)
CA (1) CA3112505C (fr)
CL (1) CL2021000656A1 (fr)
CO (1) CO2021003290A2 (fr)
ES (1) ES2948810T3 (fr)
IL (1) IL281105B (fr)
MX (1) MX2021002932A (fr)
PT (1) PT3852525T (fr)
WO (1) WO2020058324A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11697799B2 (en) 2019-04-15 2023-07-11 Ossium Health, Inc. System and method for extraction and cryopreservation of bone marrow
WO2021071430A1 (fr) * 2019-10-08 2021-04-15 Cellresearch Corporation Pte. Ltd. Formulation de stockage ou de transport de cellules souches mésenchymateuses et ses procédés de fabrication et d'utilisation
FR3105911B1 (fr) * 2020-01-02 2022-03-04 Vetbiobank Procédé de congélation et de conservation de cellules stromales néonatales
EP4181675A4 (fr) 2020-07-18 2024-04-24 Ossium Health, Inc. Perméation de corps vertébraux entiers avec un cryoprotecteur à l'aide d'une diffusion assistée par vide
CA3195653A1 (fr) 2020-10-14 2022-04-21 Ossium Health, Inc. Systemes et procedes d'extraction et de cryoconservation de moelle osseuse
WO2022133282A1 (fr) 2020-12-18 2022-06-23 Ossium Health, Inc. Procédés de thérapies cellulaires
CN113331176B (zh) * 2021-06-01 2022-04-29 零下十八度(北京)生物科技有限公司 一种脐带间充质干细胞冻存液
CN119320751B (zh) * 2024-10-31 2025-07-04 中国人民解放军总医院第二医学中心 通过外泌体miRNA调控靶基因促进间充质干细胞神经向分化的方法
CN121080478B (zh) * 2025-11-11 2026-02-06 中泽赛奥(海南)生物科技有限公司 一种间充质干细胞冻存液及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101718375B1 (ko) 2007-12-04 2017-03-22 프로테오바이오엑티브스 피티와이 엘티디 전구 세포의 보호 및 그의 분화 조절
GB0822246D0 (en) 2008-12-05 2009-01-14 Reneuron Ltd Composition
CA2932548C (fr) * 2014-01-30 2020-10-27 F. Hoffmann-La Roche Ag Stabilisation de sang total a temperature ambiante
AU2016258980B2 (en) * 2015-05-05 2022-02-17 Mesoblast International Sàrl Potency assay
PT3365432T (pt) 2015-10-23 2020-07-27 Rigshospitalet Terapêutica com células estaminais baseada em células estaminais derivadas de tecido adiposo
IL264825B (en) * 2016-08-14 2022-08-01 Univ Ramot Mesenchymal cell-derived exosomes to treat neurological disorders

Also Published As

Publication number Publication date
ES2948810T8 (en) 2025-02-26
CN112770628B (zh) 2022-07-01
CN112770628A (zh) 2021-05-07
EP3852525B1 (fr) 2023-05-10
MX2021002932A (es) 2021-06-15
IL281105A (en) 2021-04-29
CA3112505C (fr) 2023-06-20
BR112021005257B1 (pt) 2023-12-26
CA3112505A1 (fr) 2020-03-26
AU2019341538B2 (en) 2023-04-20
CL2021000656A1 (es) 2021-09-03
US20210321606A1 (en) 2021-10-21
JP7401865B2 (ja) 2023-12-20
WO2020058324A1 (fr) 2020-03-26
EP3852525A1 (fr) 2021-07-28
US20230247981A1 (en) 2023-08-10
JP2022501322A (ja) 2022-01-06
CO2021003290A2 (es) 2021-06-10
US11930808B2 (en) 2024-03-19
BR112021005257A2 (pt) 2021-06-15
IL281105B (en) 2022-05-01
ES2948810T3 (es) 2023-09-19
KR102506822B1 (ko) 2023-03-06
AU2019341538A1 (en) 2021-03-18
KR20210089140A (ko) 2021-07-15

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