PT3868741T - Composição compreendendo um composto de pirimidina e um antigénio derivado de agente patogénico - Google Patents

Composição compreendendo um composto de pirimidina e um antigénio derivado de agente patogénico

Info

Publication number
PT3868741T
PT3868741T PT211646401T PT21164640T PT3868741T PT 3868741 T PT3868741 T PT 3868741T PT 211646401 T PT211646401 T PT 211646401T PT 21164640 T PT21164640 T PT 21164640T PT 3868741 T PT3868741 T PT 3868741T
Authority
PT
Portugal
Prior art keywords
pyrimidine compound
pyrimidine
compound
Prior art date
Application number
PT211646401T
Other languages
English (en)
Original Assignee
Sumitomo Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma Co Ltd filed Critical Sumitomo Pharma Co Ltd
Publication of PT3868741T publication Critical patent/PT3868741T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Oncology (AREA)
PT211646401T 2015-10-07 2016-10-06 Composição compreendendo um composto de pirimidina e um antigénio derivado de agente patogénico PT3868741T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015199750 2015-10-07

Publications (1)

Publication Number Publication Date
PT3868741T true PT3868741T (pt) 2023-10-19

Family

ID=58487860

Family Applications (2)

Application Number Title Priority Date Filing Date
PT168536860T PT3360864T (pt) 2015-10-07 2016-10-06 Composto de pirimidina
PT211646401T PT3868741T (pt) 2015-10-07 2016-10-06 Composição compreendendo um composto de pirimidina e um antigénio derivado de agente patogénico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT168536860T PT3360864T (pt) 2015-10-07 2016-10-06 Composto de pirimidina

Country Status (20)

Country Link
US (5) US10632192B2 (pt)
EP (2) EP3360864B1 (pt)
JP (3) JP6769976B2 (pt)
KR (1) KR102651207B1 (pt)
CN (1) CN108290845B (pt)
AU (1) AU2016334826B2 (pt)
CA (1) CA3001283C (pt)
CY (1) CY1124542T1 (pt)
DK (2) DK3868741T3 (pt)
ES (2) ES2960724T3 (pt)
FI (1) FI3868741T3 (pt)
HU (2) HUE055079T2 (pt)
MY (1) MY194902A (pt)
PH (1) PH12018500755A1 (pt)
PL (2) PL3868741T3 (pt)
PT (2) PT3360864T (pt)
RU (1) RU2759917C2 (pt)
SG (1) SG11201802832UA (pt)
TW (1) TWI718188B (pt)
WO (1) WO2017061532A1 (pt)

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WO2020178769A1 (en) 2019-03-07 2020-09-10 Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. 2'3'-cyclic dinucleotides and prodrugs thereof
CN113574063B (zh) 2019-03-07 2025-03-18 捷克共和国有机化学与生物化学研究所 3’3’-环二核苷酸及其前药
WO2020178768A1 (en) 2019-03-07 2020-09-10 Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. 3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
KR102921677B1 (ko) * 2019-04-05 2026-02-02 스미토모 파마 가부시키가이샤 수용성 보조제
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
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Also Published As

Publication number Publication date
HUE055079T2 (hu) 2021-10-28
PH12018500755A1 (en) 2018-10-15
PL3360864T3 (pl) 2021-10-25
ES2870679T3 (es) 2021-10-27
US20260053911A1 (en) 2026-02-26
MY194902A (en) 2022-12-22
RU2018116351A3 (pt) 2020-02-25
JP7195398B2 (ja) 2022-12-23
TWI718188B (zh) 2021-02-11
CA3001283A1 (en) 2017-04-13
ES2960724T3 (es) 2024-03-06
CA3001283C (en) 2023-10-10
US11266738B2 (en) 2022-03-08
US20180280499A1 (en) 2018-10-04
PL3868741T3 (pl) 2024-01-29
CN108290845B (zh) 2021-08-03
DK3868741T3 (da) 2023-11-06
KR102651207B1 (ko) 2024-03-25
SG11201802832UA (en) 2018-05-30
US20240245766A1 (en) 2024-07-25
US20220226468A1 (en) 2022-07-21
EP3868741B1 (en) 2023-08-30
WO2017061532A1 (ja) 2017-04-13
CY1124542T1 (el) 2022-07-22
AU2016334826A1 (en) 2018-05-10
KR20180056774A (ko) 2018-05-29
US20210008197A1 (en) 2021-01-14
RU2759917C2 (ru) 2021-11-18
HK1255921A1 (en) 2019-09-06
AU2016334826B2 (en) 2020-08-27
RU2018116351A (ru) 2019-11-07
EP3360864B1 (en) 2021-04-28
EP3360864A4 (en) 2019-05-29
EP3360864A1 (en) 2018-08-15
JPWO2017061532A1 (ja) 2018-08-02
JP2021001210A (ja) 2021-01-07
FI3868741T3 (fi) 2023-10-02
TW201718518A (zh) 2017-06-01
DK3360864T3 (da) 2021-06-14
US12440560B2 (en) 2025-10-14
CN108290845A (zh) 2018-07-17
PT3360864T (pt) 2021-06-02
US11911466B2 (en) 2024-02-27
EP3868741A1 (en) 2021-08-25
JP6769976B2 (ja) 2020-10-14
US10632192B2 (en) 2020-04-28
HUE064322T2 (hu) 2024-03-28
JP2022010266A (ja) 2022-01-14

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