PT4065582T - Derivados polimórficos do carbazol e utilizações dos mesmos - Google Patents

Derivados polimórficos do carbazol e utilizações dos mesmos

Info

Publication number
PT4065582T
PT4065582T PT208284547T PT20828454T PT4065582T PT 4065582 T PT4065582 T PT 4065582T PT 208284547 T PT208284547 T PT 208284547T PT 20828454 T PT20828454 T PT 20828454T PT 4065582 T PT4065582 T PT 4065582T
Authority
PT
Portugal
Prior art keywords
polymorphic
carbazole derivatives
carbazole
derivatives
polymorphic carbazole
Prior art date
Application number
PT208284547T
Other languages
English (en)
Original Assignee
Ikena Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ikena Oncology Inc filed Critical Ikena Oncology Inc
Publication of PT4065582T publication Critical patent/PT4065582T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT208284547T 2019-11-26 2020-11-25 Derivados polimórficos do carbazol e utilizações dos mesmos PT4065582T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962940481P 2019-11-26 2019-11-26

Publications (1)

Publication Number Publication Date
PT4065582T true PT4065582T (pt) 2025-05-22

Family

ID=73856339

Family Applications (1)

Application Number Title Priority Date Filing Date
PT208284547T PT4065582T (pt) 2019-11-26 2020-11-25 Derivados polimórficos do carbazol e utilizações dos mesmos

Country Status (14)

Country Link
US (3) US11591339B2 (pt)
EP (2) EP4065582B1 (pt)
JP (2) JP2023502531A (pt)
KR (1) KR20220125231A (pt)
CN (1) CN115279764B (pt)
AU (1) AU2020394424A1 (pt)
CA (1) CA3159317A1 (pt)
ES (1) ES3028099T3 (pt)
FI (1) FI4065582T3 (pt)
IL (1) IL293326A (pt)
MX (1) MX2022006308A (pt)
PL (1) PL4065582T3 (pt)
PT (1) PT4065582T (pt)
WO (1) WO2021108528A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018195397A2 (en) 2017-04-21 2018-10-25 Kyn Therapeutics Indole ahr inhibitors and uses thereof
PT4065582T (pt) 2019-11-26 2025-05-22 Ikena Oncology Inc Derivados polimórficos do carbazol e utilizações dos mesmos
WO2021236717A1 (en) 2020-05-20 2021-11-25 Senda Biosciences, Inc. Fused imidazole derivatives as ahr antagonists

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Also Published As

Publication number Publication date
US20250276975A1 (en) 2025-09-04
US12162884B2 (en) 2024-12-10
US20210253579A1 (en) 2021-08-19
EP4529955A3 (en) 2025-07-16
CN115279764A (zh) 2022-11-01
FI4065582T3 (fi) 2025-05-25
KR20220125231A (ko) 2022-09-14
US11591339B2 (en) 2023-02-28
EP4065582A1 (en) 2022-10-05
WO2021108528A1 (en) 2021-06-03
IL293326A (en) 2022-07-01
AU2020394424A1 (en) 2022-06-16
EP4065582B1 (en) 2025-02-19
US20230286990A1 (en) 2023-09-14
EP4529955A2 (en) 2025-04-02
JP2025113368A (ja) 2025-08-01
PL4065582T3 (pl) 2025-08-18
MX2022006308A (es) 2022-06-22
CN115279764B (zh) 2026-04-07
ES3028099T3 (en) 2025-06-18
JP2023502531A (ja) 2023-01-24
CA3159317A1 (en) 2021-06-03

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