PT68372A - Process for the selective n-protection of aminoglycosides and novel selectivity protected aminoglycosid intermediates - Google Patents

Process for the selective n-protection of aminoglycosides and novel selectivity protected aminoglycosid intermediates

Info

Publication number
PT68372A
PT68372A PT68372A PT6837278A PT68372A PT 68372 A PT68372 A PT 68372A PT 68372 A PT68372 A PT 68372A PT 6837278 A PT6837278 A PT 6837278A PT 68372 A PT68372 A PT 68372A
Authority
PT
Portugal
Prior art keywords
aminoglycosid
aminoglycosides
intermediates
selective
protection
Prior art date
Application number
PT68372A
Other languages
English (en)
Inventor
John Jessen Wright
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of PT68372A publication Critical patent/PT68372A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT68372A 1977-08-05 1978-08-01 Process for the selective n-protection of aminoglycosides and novel selectivity protected aminoglycosid intermediates PT68372A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/822,118 US4282350A (en) 1977-08-05 1977-08-05 Selective 3"-N-acylation of 1,3"-di-N-unprotected-poly-N-protected-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols

Publications (1)

Publication Number Publication Date
PT68372A true PT68372A (en) 1978-09-01

Family

ID=25235190

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68372A PT68372A (en) 1977-08-05 1978-08-01 Process for the selective n-protection of aminoglycosides and novel selectivity protected aminoglycosid intermediates

Country Status (10)

Country Link
US (1) US4282350A (pt)
EP (1) EP0000800B1 (pt)
JP (1) JPS5430134A (pt)
DE (1) DE2860297D1 (pt)
DK (1) DK341078A (pt)
FI (1) FI782369A7 (pt)
GR (1) GR72425B (pt)
HU (1) HU180095B (pt)
IT (1) IT1097762B (pt)
PT (1) PT68372A (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2840907A1 (de) * 1978-09-20 1980-04-03 Bayer Ag Selektiv geschuetzte 4,6-di-o-(aminoglykosyl)-1,3-diaminocyclitole
JPS6383351U (pt) * 1986-11-20 1988-06-01
JPS63225393A (ja) * 1988-02-09 1988-09-20 Microbial Chem Res Found １位以外のアミノ基が選択的に保護されたアミノグリコシド抗生物質保護誘導体
JPH027892U (pt) * 1989-06-14 1990-01-18
EA017824B1 (ru) 2007-11-21 2013-03-29 Эйкеоджен, Инк. Антибактериальные аналоги аминогликозида
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132757A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
DE202013011690U1 (de) 2013-04-05 2014-02-26 Isabellenhütte Heusler Gmbh & Co. Kg Messwiderstand
CN106866756A (zh) * 2017-01-10 2017-06-20 苏利制药科技江阴有限公司 一种合成1‑n‑乙基西索米星的方法
CN113960183A (zh) * 2020-12-28 2022-01-21 常州方圆制药有限公司 依替米星中间体中乙酰化杂质的检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5644076B2 (pt) * 1973-07-12 1981-10-16
CH606076A5 (pt) * 1973-08-06 1978-10-13 Scherico Ltd
US4063015A (en) * 1973-08-27 1977-12-13 Schering Corporation Garamine and derivatives thereof
JPS5512039B2 (pt) * 1974-03-22 1980-03-29
US4044123A (en) * 1975-05-02 1977-08-23 Schering Corporation 6'-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, methods for their use as antibacterial agents and compositions useful therefor
US4066752A (en) * 1976-06-21 1978-01-03 Schering Corporation 1-Desamino-1-hydroxy and 1-desamino-1-epi-hydroxy-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols; 1-desamino-1-oxo-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols, intermediates and use as antibacterial agents
DE2712160A1 (de) * 1977-03-19 1978-09-28 Bayer Ag Pseudotrisaccharide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
GR72425B (pt) 1983-11-04
FI782369A7 (fi) 1979-02-06
JPS5430134A (en) 1979-03-06
US4282350A (en) 1981-08-04
DE2860297D1 (en) 1981-02-19
EP0000800B1 (en) 1980-12-10
IT7826293A0 (it) 1978-07-28
IT1097762B (it) 1985-08-31
EP0000800A1 (en) 1979-02-21
DK341078A (da) 1979-02-06
HU180095B (en) 1983-01-28

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