PT73100A - Use of Propionibacterium spp. in tumour therapy - in form of cell-wall or whole-cell preparations - Google Patents
Use of Propionibacterium spp. in tumour therapy - in form of cell-wall or whole-cell preparationsInfo
- Publication number
- PT73100A PT73100A PT7310081A PT7310081A PT73100A PT 73100 A PT73100 A PT 73100A PT 7310081 A PT7310081 A PT 7310081A PT 7310081 A PT7310081 A PT 7310081A PT 73100 A PT73100 A PT 73100A
- Authority
- PT
- Portugal
- Prior art keywords
- cell
- whole
- wall
- prepns
- tumour therapy
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 210000002421 cell wall Anatomy 0.000 title abstract 3
- 241000186429 Propionibacterium Species 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 241001464974 Cutibacterium avidum Species 0.000 abstract 2
- 241001464975 Cutibacterium granulosum Species 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241000186427 Cutibacterium acnes Species 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 abstract 1
- 230000002601 intratumoral effect Effects 0.000 abstract 1
- 239000002953 phosphate buffered saline Substances 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The use of Propionibacterium granulosum, P.avidum and/or P.acnes for prodn. of cell-wall or whole-cell prepns. in the radio- or chemotheraphy of tumours is claimed. Pref. strains are P. granulosum KP45 (DSM 1773) and P.avidum KP40 (DSM 1772). Prepns. for i.p., i.v., or intratumoral admin. pref. contain 0.5-50 (esp. 5-7.5) mg/ml. of killed cells or cell walls suspended in phosphate-buffered saline (pH 7.2). The prepns. increase tolerance to radiation, promote tumour regression and increase resistance to bacterial infection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT7310081A PT73100B (en) | 1981-05-29 | 1981-05-29 | USE OF PROPIONIBAKTERIA |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT7310081A PT73100B (en) | 1981-05-29 | 1981-05-29 | USE OF PROPIONIBAKTERIA |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT73100A true PT73100A (en) | 1981-06-01 |
| PT73100B PT73100B (en) | 1982-07-05 |
Family
ID=20082932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT7310081A PT73100B (en) | 1981-05-29 | 1981-05-29 | USE OF PROPIONIBAKTERIA |
Country Status (1)
| Country | Link |
|---|---|
| PT (1) | PT73100B (en) |
-
1981
- 1981-05-29 PT PT7310081A patent/PT73100B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT73100B (en) | 1982-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19970131 |