PT775135E - Derivados de 3-azabiciclo(3.2.0)heptano substituidos em n uteis como neurolepticos - Google Patents

Derivados de 3-azabiciclo(3.2.0)heptano substituidos em n uteis como neurolepticos

Info

Publication number
PT775135E
PT775135E PT95926970T PT95926970T PT775135E PT 775135 E PT775135 E PT 775135E PT 95926970 T PT95926970 T PT 95926970T PT 95926970 T PT95926970 T PT 95926970T PT 775135 E PT775135 E PT 775135E
Authority
PT
Portugal
Prior art keywords
azabicyclo
pct
derivatives
neuroleptics
heptan
Prior art date
Application number
PT95926970T
Other languages
English (en)
Portuguese (pt)
Inventor
Gerd Steiner
Rainer Munschauer
Thomas Hoger
Hans-Jurgen Teschendorf
Liliane Hoger
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of PT775135E publication Critical patent/PT775135E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT95926970T 1994-08-04 1995-07-21 Derivados de 3-azabiciclo(3.2.0)heptano substituidos em n uteis como neurolepticos PT775135E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4427648A DE4427648A1 (de) 1994-08-04 1994-08-04 N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
PT775135E true PT775135E (pt) 2003-10-31

Family

ID=6524944

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95926970T PT775135E (pt) 1994-08-04 1995-07-21 Derivados de 3-azabiciclo(3.2.0)heptano substituidos em n uteis como neurolepticos

Country Status (25)

Country Link
US (1) US6028073A (de)
EP (1) EP0775135B1 (de)
JP (1) JPH10503503A (de)
CN (1) CN1066145C (de)
AT (1) ATE242236T1 (de)
AU (1) AU696230B2 (de)
BG (1) BG63633B1 (de)
CA (1) CA2196809A1 (de)
CZ (1) CZ287862B6 (de)
DE (2) DE4427648A1 (de)
DK (1) DK0775135T3 (de)
ES (1) ES2201111T3 (de)
FI (1) FI970448A7 (de)
HR (1) HRP950438A2 (de)
HU (1) HUT77772A (de)
MX (1) MX9700807A (de)
NO (1) NO312243B1 (de)
NZ (1) NZ290426A (de)
PL (1) PL183526B1 (de)
PT (1) PT775135E (de)
RU (1) RU2163604C2 (de)
SI (1) SI9520094B (de)
UA (1) UA44903C2 (de)
WO (1) WO1996004272A1 (de)
ZA (1) ZA956477B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458821B1 (en) * 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836406A1 (de) 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19848521A1 (de) * 1998-10-21 2000-04-27 Basf Ag Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
DE19854147A1 (de) * 1998-11-24 2000-05-25 Basf Ag Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht
EP1812389B1 (de) * 2004-10-14 2011-08-17 Abbott GmbH & Co. KG Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen
TW200845977A (en) * 2007-03-30 2008-12-01 Targacept Inc Sub-type selective azabicycloalkane derivatives
CN105473554B (zh) * 2013-07-10 2019-08-13 沃泰克斯药物股份有限公司 作为离子通道调节剂的稠合的哌啶酰胺类
AU2015279377B2 (en) * 2014-06-26 2019-09-12 F. Hoffmann-La Roche Ag Indolin-2-one or pyrrolo-pyridin-2-one derivatives
EP3371170B1 (de) 2015-11-06 2019-07-31 H. Hoffnabb-La Roche Ag Indolin-2-on-derivate zur behandlung von erkrankungen des zentralen nervensystems (zns)
PH12018500978B1 (en) 2015-11-06 2023-05-05 Hoffmann La Roche Indolin-2-one derivatives
WO2017076931A1 (en) 2015-11-06 2017-05-11 F. Hoffmann-La Roche Ag Indolin-2-one derivatives for use in the treatment of cns and related disorders
CN108137561B (zh) 2015-11-06 2021-03-26 豪夫迈·罗氏有限公司 二氢吲哚-2-酮衍生物
CN112010859B (zh) * 2019-05-30 2022-07-19 中国科学院上海药物研究所 一种并环化合物、其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4243287A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
ES2201111T3 (es) 2004-03-16
ZA956477B (en) 1997-02-03
EP0775135B1 (de) 2003-06-04
NZ290426A (en) 1998-02-26
WO1996004272A1 (de) 1996-02-15
CN1156454A (zh) 1997-08-06
NO970473D0 (no) 1997-02-03
AU3116295A (en) 1996-03-04
AU696230B2 (en) 1998-09-03
BG63633B1 (bg) 2002-07-31
HUT77772A (hu) 1998-08-28
FI970448L (fi) 1997-04-03
SI9520094A (en) 1997-08-31
SI9520094B (sl) 2002-02-28
NO312243B1 (no) 2002-04-15
PL318460A1 (en) 1997-06-09
FI970448A7 (fi) 1997-04-03
DK0775135T3 (da) 2003-09-29
UA44903C2 (uk) 2002-03-15
BG101220A (bg) 1997-08-29
RU2163604C2 (ru) 2001-02-27
PL183526B1 (pl) 2002-06-28
CA2196809A1 (en) 1996-02-15
MX9700807A (es) 1997-05-31
EP0775135A1 (de) 1997-05-28
HRP950438A2 (en) 1997-10-31
US6028073A (en) 2000-02-22
FI970448A0 (fi) 1997-02-03
CN1066145C (zh) 2001-05-23
JPH10503503A (ja) 1998-03-31
DE59510713D1 (de) 2003-07-10
CZ287862B6 (en) 2001-02-14
NO970473L (no) 1997-04-01
DE4427648A1 (de) 1996-02-08
ATE242236T1 (de) 2003-06-15
CZ31097A3 (en) 1997-10-15

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