PT82020B - Processo para a preparacao de eter 4-(2-metoxietil)-fenilglicidilico e/ou metoprolol - Google Patents

Processo para a preparacao de eter 4-(2-metoxietil)-fenilglicidilico e/ou metoprolol

Info

Publication number: PT82020B
Authority: PT; Portugal
Prior art keywords: methoxyethyl; metoprolol; ether; phenylglycidylate; pharmaceutically acceptable
Prior art date: 1985-02-13

Application number

PT82020A

Other languages

English (en)

Other versions

PT82020A (en

Original Assignee

Shell Int Research

Gist Brocades Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-02-13

Filing date

1986-02-12

Publication date

1987-12-30

1986-02-12 Application filed by Shell Int Research, Gist Brocades Nv filed Critical Shell Int Research

1986-03-01 Publication of PT82020A publication Critical patent/PT82020A/pt

1987-12-30 Publication of PT82020B publication Critical patent/PT82020B/pt

Links

IUBSYMUCCVWXPE-UHFFFAOYSA-N metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 title abstract 4
229960002237 metoprolol Drugs 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title 2
-1 2-METHOXYETHYL Chemical class 0.000 title 1
UEOWFGJMGUIGHC-UHFFFAOYSA-N 2-[[4-(2-methoxyethyl)phenoxy]methyl]oxirane Chemical compound C1=CC(CCOC)=CC=C1OCC1OC1 UEOWFGJMGUIGHC-UHFFFAOYSA-N 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
230000000707 stereoselective effect Effects 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
238000006735 epoxidation reaction Methods 0.000 abstract 1
JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Epoxy Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Liquid Crystal (AREA)
Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)

PT82020A 1985-02-13 1986-02-12 Processo para a preparacao de eter 4-(2-metoxietil)-fenilglicidilico e/ou metoprolol PT82020B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB858503666A GB8503666D0 (en)	1985-02-13	1985-02-13	Producing 4-(2-methoxyethyl)-phenylglycidyl ether

Publications (2)

Publication Number	Publication Date
PT82020A PT82020A (en)	1986-03-01
PT82020B true PT82020B (pt)	1987-12-30

Family

ID=10574403

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT82020A PT82020B (pt)	1985-02-13	1986-02-12	Processo para a preparacao de eter 4-(2-metoxietil)-fenilglicidilico e/ou metoprolol

Country Status (16)

Country	Link
EP (1)	EP0193228B1 (pt)
JP (1)	JPS61254194A (pt)
CN (1)	CN86100965A (pt)
AT (1)	ATE47713T1 (pt)
AU (1)	AU593232B2 (pt)
DE (1)	DE3666694D1 (pt)
DK (1)	DK67886A (pt)
ES (1)	ES8706204A1 (pt)
FI (1)	FI86891C (pt)
GB (1)	GB8503666D0 (pt)
GR (1)	GR860401B (pt)
HU (1)	HU201117B (pt)
NO (1)	NO860508L (pt)
NZ (1)	NZ215066A (pt)
PT (1)	PT82020B (pt)
ZA (1)	ZA86740B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1240942A (en) *	1984-05-28	1988-08-23	Keizo Furuhashi	Process for the preparation of epoxides by means of microorganisms
DE3778662D1 (de) *	1986-11-14	1992-06-04	Ciba Geigy Ag	Orales osmotisches system fuer metoprolol mit verbesserten formulierungseigenschaften.
GB8917496D0 (en) *	1989-07-31	1989-09-13	Ici Plc	Microbiological production of 2,3-epoxypropyl ethers
FR2760747B1 (fr) *	1997-03-12	1999-06-04	Organisation Nationale Interpr	Procede de fabrication de glycidol ou d'un compose glycidyle
WO1999007199A2 (de) *	1997-08-08	1999-02-18	Lonza Ag	Verfahren zur herstellung von l-alaninol und gamma-glutamylisopropylamid und mikroorganismusstamm des genus pseudomonas

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1458392A (en) *	1973-11-09	1976-12-15	Ici Ltd	Optically-active 1-aryloxy-2,3-epoxypropane derivatives

1985
- 1985-02-13 GB GB858503666A patent/GB8503666D0/en active Pending
1986
- 1986-01-31 ZA ZA86740A patent/ZA86740B/xx unknown
- 1986-02-06 AU AU53269/86A patent/AU593232B2/en not_active Ceased
- 1986-02-07 NZ NZ215066A patent/NZ215066A/en unknown
- 1986-02-10 FI FI860599A patent/FI86891C/fi not_active IP Right Cessation
- 1986-02-11 DE DE8686200199T patent/DE3666694D1/de not_active Expired
- 1986-02-11 AT AT86200199T patent/ATE47713T1/de not_active IP Right Cessation
- 1986-02-11 EP EP86200199A patent/EP0193228B1/en not_active Expired
- 1986-02-11 GR GR860401A patent/GR860401B/el unknown
- 1986-02-12 HU HU86608A patent/HU201117B/hu not_active IP Right Cessation
- 1986-02-12 DK DK67886A patent/DK67886A/da not_active Application Discontinuation
- 1986-02-12 PT PT82020A patent/PT82020B/pt not_active IP Right Cessation
- 1986-02-12 NO NO860508A patent/NO860508L/no unknown
- 1986-02-13 JP JP61029840A patent/JPS61254194A/ja active Pending
- 1986-02-13 ES ES551926A patent/ES8706204A1/es not_active Expired
- 1986-02-13 CN CN198686100965A patent/CN86100965A/zh active Pending

Also Published As

Publication number	Publication date
EP0193228B1 (en)	1989-11-02
HU201117B (en)	1990-09-28
FI860599L (fi)	1986-08-14
HUT40169A (en)	1986-11-28
DK67886D0 (da)	1986-02-12
CN86100965A (zh)	1986-10-01
ATE47713T1 (de)	1989-11-15
DK67886A (da)	1986-08-14
AU593232B2 (en)	1990-02-08
ZA86740B (en)	1986-10-29
PT82020A (en)	1986-03-01
JPS61254194A (ja)	1986-11-11
EP0193228A1 (en)	1986-09-03
GB8503666D0 (en)	1985-03-13
FI86891B (fi)	1992-07-15
DE3666694D1 (en)	1989-12-07
GR860401B (en)	1986-06-12
AU5326986A (en)	1986-08-21
ES551926A0 (es)	1987-06-01
FI860599A0 (fi)	1986-02-10
FI86891C (fi)	1992-10-26
ES8706204A1 (es)	1987-06-01
NZ215066A (en)	1988-02-29
NO860508L (no)	1986-08-14

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Legal Events

Date

Code

Title

Description

1994-05-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19931231