PT854708E - Alcoois lipidicos como novos medicamentos imunossupressores - Google Patents

Alcoois lipidicos como novos medicamentos imunossupressores

Info

Publication number: PT854708E
Authority: PT; Portugal
Prior art keywords: alcohols; oxicarbonyl; carbonylamido; amidocarbonyl; alkylmercapto
Prior art date: 1995-10-14

Application number

PT96934651T

Other languages

English (en)

Inventor

Harald Zilch

Dieter Herrmann

Hans-Georg Opitz

Original Assignee

Heidelberg Pharma Holding Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-14

Filing date

1996-10-11

Publication date

2002-06-28

1996-10-11 Application filed by Heidelberg Pharma Holding Gmbh filed Critical Heidelberg Pharma Holding Gmbh

2002-06-28 Publication of PT854708E publication Critical patent/PT854708E/pt

Links

150000001298 alcohols Chemical class 0.000 title 1
239000003814 drug Substances 0.000 title 1
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 2
125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
239000005864 Sulphur Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000005708 carbonyloxy group Chemical group [*:2]OC([*:1])=O 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
229920006395 saturated elastomer Polymers 0.000 abstract 2
125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 2
125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 2
125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
-1 lipid alcohols Chemical class 0.000 abstract 1
239000008177 pharmaceutical agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Virology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PT96934651T 1995-10-14 1996-10-11 Alcoois lipidicos como novos medicamentos imunossupressores PT854708E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19538402A DE19538402A1 (de)	1995-10-14	1995-10-14	Lipidalkohole als neue immunsuppressive und antivirale Arzneimittel

Publications (1)

Publication Number	Publication Date
PT854708E true PT854708E (pt)	2002-06-28

Family

ID=7774931

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT96934651T PT854708E (pt)	1995-10-14	1996-10-11	Alcoois lipidicos como novos medicamentos imunossupressores

Country Status (18)

Country	Link
US (1)	US6177469B1 (pt)
EP (1)	EP0854708B1 (pt)
JP (1)	JPH11513677A (pt)
KR (1)	KR19990064240A (pt)
AT (1)	ATE210434T1 (pt)
AU (1)	AU722835B2 (pt)
CA (1)	CA2234244A1 (pt)
DE (2)	DE19538402A1 (pt)
DK (1)	DK0854708T3 (pt)
ES (1)	ES2169816T3 (pt)
HU (1)	HUP9900725A3 (pt)
IL (1)	IL123915A (pt)
NO (1)	NO981629L (pt)
NZ (1)	NZ320211A (pt)
PT (1)	PT854708E (pt)
TW (1)	TW426513B (pt)
WO (1)	WO1997014410A1 (pt)
ZA (1)	ZA968597B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1293795B1 (it) *	1997-07-28	1999-03-10	Angelini Ricerche Spa	Farmaco attivo nel ridurre la produzione di proteina mcp-1
US6406722B1 (en)	1999-02-18	2002-06-18	Robert G. Gallaher	Method of treating viral infections and lesions with taxane compounds
HUP0303719A2 (hu) *	2000-10-16	2004-03-01	Neopharm, Inc.	Mitoxantron hatóanyag-tartalmú liposzómás gyógyszerkészítmények és eljárás az előállításukra
WO2006115509A2 (en)	2004-06-24	2006-11-02	Novartis Vaccines And Diagnostics Inc.	Small molecule immunopotentiators and assays for their detection
US7341985B2 (en) *	2004-10-08	2008-03-11	Air Products And Chemicals, Inc.	2-Hydroxy-3-alkoxypropyl sulfides, sulfones, and sulfoxides: new surface active agents
WO2009129395A1 (en) *	2008-04-16	2009-10-22	Abbott Laboratories	Cationic lipids and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4857511A (en) *	1985-09-17	1989-08-15	Burroughs Wellcome Co.	Treatment of human viral infections
DE3638126A1 (de) *	1986-11-08	1988-05-11	Nattermann A & Cie	Mercaptoalkanolphospholipide und deren derivate, verfahren zu ihrer herstellung und ihre verwendung als wirkstoffe in arzneimitteln
US4997851A (en) *	1987-12-31	1991-03-05	Isaacs Charles E	Antiviral and antibacterial activity of fatty acids and monoglycerides
DE3929217A1 (de) *	1989-09-02	1991-03-07	Boehringer Mannheim Gmbh	Verwendung von phospholipid-derivaten als antivirale arzneimittel und neue phospholipide
DE3934820A1 (de) *	1989-10-19	1991-04-25	Boehringer Mannheim Gmbh	Verwendung von lecithin-analoga als antivirale arzneimittel und neue derivate

1995
- 1995-10-14 DE DE19538402A patent/DE19538402A1/de not_active Withdrawn
1996
- 1996-10-11 NZ NZ320211A patent/NZ320211A/xx unknown
- 1996-10-11 IL IL12391596A patent/IL123915A/xx not_active IP Right Cessation
- 1996-10-11 ES ES96934651T patent/ES2169816T3/es not_active Expired - Lifetime
- 1996-10-11 EP EP96934651A patent/EP0854708B1/de not_active Expired - Lifetime
- 1996-10-11 KR KR1019980702727A patent/KR19990064240A/ko not_active Ceased
- 1996-10-11 WO PCT/EP1996/004438 patent/WO1997014410A1/de not_active Ceased
- 1996-10-11 DE DE59608464T patent/DE59608464D1/de not_active Expired - Fee Related
- 1996-10-11 AU AU72912/96A patent/AU722835B2/en not_active Ceased
- 1996-10-11 JP JP9515499A patent/JPH11513677A/ja not_active Ceased
- 1996-10-11 DK DK96934651T patent/DK0854708T3/da active
- 1996-10-11 ZA ZA9608597A patent/ZA968597B/xx unknown
- 1996-10-11 HU HU9900725A patent/HUP9900725A3/hu unknown
- 1996-10-11 US US09/051,088 patent/US6177469B1/en not_active Expired - Fee Related
- 1996-10-11 AT AT96934651T patent/ATE210434T1/de not_active IP Right Cessation
- 1996-10-11 CA CA002234244A patent/CA2234244A1/en not_active Abandoned
- 1996-10-11 PT PT96934651T patent/PT854708E/pt unknown
- 1996-10-14 TW TW085112614A patent/TW426513B/zh not_active IP Right Cessation
1998
- 1998-04-08 NO NO981629A patent/NO981629L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO981629D0 (no)	1998-04-08
EP0854708A1 (de)	1998-07-29
NO981629L (no)	1998-06-12
IL123915A (en)	2003-01-12
KR19990064240A (ko)	1999-07-26
WO1997014410A1 (de)	1997-04-24
ES2169816T3 (es)	2002-07-16
DE19538402A1 (de)	1997-04-17
CA2234244A1 (en)	1997-04-24
JPH11513677A (ja)	1999-11-24
TW426513B (en)	2001-03-21
DK0854708T3 (da)	2002-04-08
EP0854708B1 (de)	2001-12-12
HUP9900725A3 (en)	2001-08-28
HUP9900725A2 (hu)	1999-06-28
AU722835B2 (en)	2000-08-10
ATE210434T1 (de)	2001-12-15
NZ320211A (en)	2000-01-28
AU7291296A (en)	1997-05-07
DE59608464D1 (de)	2002-01-24
ZA968597B (en)	1998-04-14
US6177469B1 (en)	2001-01-23

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