PT87063A - Heterocyclic compounds and their preparation and use - Google Patents
Heterocyclic compounds and their preparation and useInfo
- Publication number
- PT87063A PT87063A PT87063A PT8706388A PT87063A PT 87063 A PT87063 A PT 87063A PT 87063 A PT87063 A PT 87063A PT 8706388 A PT8706388 A PT 8706388A PT 87063 A PT87063 A PT 87063A
- Authority
- PT
- Portugal
- Prior art keywords
- compounds
- preparation
- heterocyclic compounds
- chem
- so2nh2
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 Heterocyclic dihydroxyquinoxaline compounds Chemical class 0.000 abstract 1
- 229910003204 NH2 Inorganic materials 0.000 abstract 1
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
- 229910006069 SO3H Inorganic materials 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000002964 excitative effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 208000013403 hyperactivity Diseases 0.000 abstract 1
- 239000002858 neurotransmitter agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK146787A DK146787A (da) | 1987-03-23 | 1987-03-23 | Heterocykliske forbindelser, deres fremstilling og anvendelse |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT87063A true PT87063A (pt) | 1988-04-01 |
| PT87063B PT87063B (pt) | 1992-07-31 |
Family
ID=8105140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87063A PT87063B (pt) | 1987-03-23 | 1988-03-23 | Processo de preparacao de compostos heterociclicosdi-hidroxiquinoxalina e de composicoes farmaceuticas que os contem |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4889855A (pt) |
| EP (1) | EP0283959B1 (pt) |
| KR (1) | KR960003324B1 (pt) |
| AT (1) | ATE71090T1 (pt) |
| AU (1) | AU596737B2 (pt) |
| CA (1) | CA1315789C (pt) |
| DE (1) | DE3867268D1 (pt) |
| DK (1) | DK146787A (pt) |
| ES (1) | ES2037753T3 (pt) |
| FI (1) | FI92582C (pt) |
| GR (1) | GR3003910T3 (pt) |
| IE (1) | IE60002B1 (pt) |
| IL (1) | IL85328A (pt) |
| NO (1) | NO174549C (pt) |
| NZ (1) | NZ223776A (pt) |
| PH (1) | PH23979A (pt) |
| PT (1) | PT87063B (pt) |
| ZA (1) | ZA881139B (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743607A (en) * | 1987-05-29 | 1988-05-10 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic tricyclic imidazolones |
| NO179551C (no) * | 1987-11-10 | 1996-10-30 | Novo Nordisk As | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
| DK160941C (da) * | 1988-06-28 | 1991-10-21 | Novo Nordisk As | Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar |
| DK715888D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| DK716188D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| US5308845A (en) * | 1988-12-22 | 1994-05-03 | Novo Nordisk A/S | Quinoxaline compounds and their preparation and use |
| PT99864B (pt) | 1990-12-21 | 1999-06-30 | Schering Ag | Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato |
| DK73091D0 (da) * | 1991-04-22 | 1991-04-22 | Novo Nordisk As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| CA2115442C (en) * | 1991-09-09 | 2003-09-23 | Christopher Franklin Bigge | Pharmaceutical preparation containing an uricosuric agent and an excitatory amino acid antagonist |
| DE4217952A1 (de) * | 1992-05-30 | 1993-12-02 | Basf Ag | Chinoxalin-2,3(1H,4H)-dione |
| EP0647137B1 (en) * | 1992-06-22 | 2008-08-13 | The Regents Of The University Of California | Glycine receptor antagonists and the use thereof |
| ATE157977T1 (de) * | 1992-10-13 | 1997-09-15 | Warner Lambert Co | Chinoxalinderivate als eaa antagonisten |
| DK12293D0 (da) * | 1993-02-02 | 1993-02-02 | Novo Nordisk As | Heterocykliske forbindelser og deres fremstilling og anvendelse |
| US5843945A (en) * | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
| WO1994026747A1 (en) * | 1993-05-13 | 1994-11-24 | Neurosearch A/S | Ampa antagonists and a method of treatment therewith |
| US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
| GB9419318D0 (en) * | 1994-09-24 | 1994-11-09 | Pfizer Ltd | Therapeutic agents |
| DE4436852A1 (de) * | 1994-10-14 | 1996-04-18 | Basf Ag | Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung |
| AU4152296A (en) * | 1994-12-07 | 1996-06-26 | Warner-Lambert Company | Novel glutamate receptor antagonists: fused cycloalkylquinoxalinediones |
| US5721234A (en) * | 1994-12-07 | 1998-02-24 | Warner-Lambert Company | Glutamate receptor antagonists: fused cycloalkylouinoxalinediones |
| JPH11501619A (ja) * | 1995-02-15 | 1999-02-09 | ベアーズデン バイオ，インコーポレイテッド | アルキルカルボキシアミノ酸−カイネートレセプターのモジュレーター |
| AU4423496A (en) * | 1995-03-14 | 1996-10-02 | Warner-Lambert Company | Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones |
| US5719153A (en) * | 1995-08-15 | 1998-02-17 | American Home Products Corporation | 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones |
| AU3571997A (en) * | 1996-08-01 | 1998-02-25 | Warner-Lambert Company | Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones |
| FR2752163B1 (fr) * | 1996-08-12 | 1998-10-30 | Pf Medicament | Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington |
| US5968928A (en) * | 1996-09-19 | 1999-10-19 | Warner-Lambert Company | Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof |
| EP3427729A1 (en) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
| JPWO2023042888A1 (pt) | 2021-09-15 | 2023-03-23 | ||
| EP4403184A4 (en) | 2021-09-15 | 2025-09-24 | Univ Of The Ryukyus | PHARMACEUTICAL COMPOSITION INTENDED FOR USE IN THE TREATMENT OF EITHER THE DECLINE OF COGNITIVE FUNCTIONS OR OVERWEIGHT OR OBESITY |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3431111A (en) * | 1963-06-10 | 1969-03-04 | Eastman Kodak Co | Cyanine dyes |
| US3772273A (en) * | 1969-01-17 | 1973-11-13 | Allied Chem | Derivatives of quinoxaline |
| US3962440A (en) * | 1973-12-26 | 1976-06-08 | Eli Lilly And Company | Quinoxaline compounds as hypnotic agents |
| US4430502A (en) * | 1982-08-13 | 1984-02-07 | The Upjohn Company | Pyridinyl substituted benzimidazoles and quinoxalines |
| FR2583751B1 (fr) * | 1985-06-20 | 1989-10-13 | Panmedica | Nouveaux antibacteriens contenant des derives des acides oxo-4-pyridine carboxyliques et leur procede de preparation |
-
1987
- 1987-03-23 DK DK146787A patent/DK146787A/da not_active IP Right Cessation
-
1988
- 1988-02-05 IL IL85328A patent/IL85328A/xx not_active IP Right Cessation
- 1988-02-16 US US07/156,539 patent/US4889855A/en not_active Expired - Lifetime
- 1988-02-18 ZA ZA881139A patent/ZA881139B/xx unknown
- 1988-02-18 IE IE43988A patent/IE60002B1/en not_active IP Right Cessation
- 1988-02-22 FI FI880816A patent/FI92582C/fi not_active IP Right Cessation
- 1988-02-26 PH PH36561A patent/PH23979A/en unknown
- 1988-03-07 NZ NZ223776A patent/NZ223776A/xx unknown
- 1988-03-17 CA CA000561757A patent/CA1315789C/en not_active Expired - Fee Related
- 1988-03-18 EP EP88104379A patent/EP0283959B1/en not_active Expired - Lifetime
- 1988-03-18 AU AU13260/88A patent/AU596737B2/en not_active Ceased
- 1988-03-18 DE DE8888104379T patent/DE3867268D1/de not_active Expired - Lifetime
- 1988-03-18 AT AT88104379T patent/ATE71090T1/de not_active IP Right Cessation
- 1988-03-18 ES ES198888104379T patent/ES2037753T3/es not_active Expired - Lifetime
- 1988-03-22 NO NO881264A patent/NO174549C/no unknown
- 1988-03-22 KR KR1019880003024A patent/KR960003324B1/ko not_active Expired - Fee Related
- 1988-03-23 PT PT87063A patent/PT87063B/pt active IP Right Grant
-
1989
- 1989-05-03 US US07/347,141 patent/US4912108A/en not_active Expired - Lifetime
-
1992
- 1992-02-27 GR GR920400325T patent/GR3003910T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI92582B (fi) | 1994-08-31 |
| US4889855A (en) | 1989-12-26 |
| EP0283959A1 (en) | 1988-09-28 |
| GR3003910T3 (pt) | 1993-03-16 |
| ES2037753T3 (es) | 1993-07-01 |
| CA1315789C (en) | 1993-04-06 |
| EP0283959B1 (en) | 1992-01-02 |
| AU596737B2 (en) | 1990-05-10 |
| IE880439L (en) | 1988-09-23 |
| NO881264D0 (no) | 1988-03-22 |
| PH23979A (en) | 1990-02-09 |
| NZ223776A (en) | 1990-10-26 |
| FI92582C (fi) | 1994-12-12 |
| KR880011125A (ko) | 1988-10-26 |
| ATE71090T1 (de) | 1992-01-15 |
| PT87063B (pt) | 1992-07-31 |
| KR960003324B1 (ko) | 1996-03-08 |
| US4912108A (en) | 1990-03-27 |
| IL85328A (en) | 1993-06-10 |
| AU1326088A (en) | 1988-09-22 |
| ZA881139B (en) | 1988-08-15 |
| NO174549C (no) | 1994-05-25 |
| DK146787A (da) | 1988-09-24 |
| DE3867268D1 (de) | 1992-02-13 |
| FI880816A0 (fi) | 1988-02-22 |
| IE60002B1 (en) | 1994-05-18 |
| DK146787D0 (da) | 1987-03-23 |
| FI880816A7 (fi) | 1988-09-24 |
| NO174549B (no) | 1994-02-14 |
| NO881264L (no) | 1988-09-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT87063A (pt) | Heterocyclic compounds and their preparation and use | |
| DK715888D0 (da) | Quinoxalinforbindelser, deres fremstilling og anvendelse | |
| DK471687A (da) | Quinoxalinforbindelser, deres fremstilling og anvendelse | |
| ATE92489T1 (de) | Imid-derivate, ihre herstellung und verwendung. | |
| DK415789D0 (da) | Tetracykliske antidepressive midler | |
| GB2233558B (en) | Psychotropic use of aromatic amines | |
| DK638787A (da) | Anthracyclinderivater, deres fremstilling og anvendelse | |
| ATE88176T1 (de) | 2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung. | |
| DE69002062D1 (de) | Verwendung von cinnamamid-derivaten zur entspannung der muskeln. | |
| ES2031921T3 (es) | Derivados 5-aminoetilados de la oxazolidinona-2, su procedimiento de fabricacion y su aplicacion terapeutica. | |
| DK142188A (da) | Heterocykliske forbindelser, deres fremstilling og anvendelse | |
| FI812773L (fi) | Foerfarande foer framstaellning av n-/4-/(2,4-diamino-6-pteridinyl)-metyl/metylamino/benzoyl/glutaminsyra | |
| ATE95697T1 (de) | Uricosuretische zusammensetzung. | |
| KR950017956A (ko) | N-치환 아자비시클로헵탄 유도체, 그의 제조 방법 및 용도 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19920109 |