PT87550A - Process for the preparation of pyrimidine derivatives and of pharmaceutical compositions containing the same - Google Patents

Process for the preparation of pyrimidine derivatives and of pharmaceutical compositions containing the same

Info

Publication number
PT87550A
PT87550A PT87550A PT8755088A PT87550A PT 87550 A PT87550 A PT 87550A PT 87550 A PT87550 A PT 87550A PT 8755088 A PT8755088 A PT 8755088A PT 87550 A PT87550 A PT 87550A
Authority
PT
Portugal
Prior art keywords
preparation
same
pharmaceutical compositions
compositions containing
pyrimidine derivatives
Prior art date
Application number
PT87550A
Other languages
English (en)
Other versions
PT87550B (pt
Inventor
Peter James Machin
Joseph Armstrong Martin
Gareth John Thomas
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT87550A publication Critical patent/PT87550A/pt
Publication of PT87550B publication Critical patent/PT87550B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PT87550A 1987-05-22 1988-05-20 Processo para a preparacao de derivados de pirimidina e de composicoes farmaceuticas que os contem PT87550B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878712115A GB8712115D0 (en) 1987-05-22 1987-05-22 Pyrimidine derivatives

Publications (2)

Publication Number Publication Date
PT87550A true PT87550A (pt) 1989-05-31
PT87550B PT87550B (pt) 1992-09-30

Family

ID=10617762

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87550A PT87550B (pt) 1987-05-22 1988-05-20 Processo para a preparacao de derivados de pirimidina e de composicoes farmaceuticas que os contem

Country Status (19)

Country Link
EP (1) EP0292023A3 (pt)
JP (1) JPS63303992A (pt)
KR (1) KR880013927A (pt)
CN (1) CN88103089A (pt)
AU (1) AU602083B2 (pt)
DK (1) DK165985C (pt)
FI (1) FI882303L (pt)
GB (1) GB8712115D0 (pt)
HU (1) HU199868B (pt)
IL (1) IL86394A0 (pt)
IS (1) IS3344A7 (pt)
MC (1) MC1934A1 (pt)
MX (1) MX11493A (pt)
NO (1) NO171065C (pt)
NZ (1) NZ224638A (pt)
PH (1) PH26909A (pt)
PT (1) PT87550B (pt)
YU (1) YU46860B (pt)
ZA (1) ZA883447B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340645C (en) * 1987-04-17 1999-07-13 Victor E. Marquez Acid stable dideoxynucleosides active against the cytopathic effects of human immunodeficiency virus
US4908440A (en) * 1987-11-12 1990-03-13 Bristol Myers Company 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides
NZ232912A (en) * 1989-03-17 1992-06-25 Oncogen Ltd Lp Synergistic composition of nucleoside derivatives for inhibiting hiv
JPH05501404A (ja) * 1989-11-06 1993-03-18 ニユコメド・アクシエセルカペト ヌクレオシド誘導体
AT400953B (de) * 1994-08-25 1996-05-28 Joern Saischek Pentofuranosid-derivate, deren herstellung und verwendung
EA200700564A1 (ru) 1998-02-25 2007-08-31 Эмори Юниверсити 2`-фторнуклеозиды
KR20090089922A (ko) 2000-10-18 2009-08-24 파마셋 인코포레이티드 바이러스 감염 및 비정상적인 세포 증식의 치료를 위한 변형된 뉴클레오시드
WO2003000200A2 (en) 2001-06-22 2003-01-03 Pharmasset Ltd. β-2'-OR 3'-HALONUCLEOSIDES
ES2327252T3 (es) 2004-08-23 2009-10-27 F. Hoffmann-La Roche Ag 4'-azido nucleosidos antivirales.
US8895531B2 (en) 2006-03-23 2014-11-25 Rfs Pharma Llc 2′-fluoronucleoside phosphonates as antiviral agents
HRP20110193T1 (hr) 2006-10-10 2011-05-31 Medivir Ab Inhibitor hcv nukleozida

Also Published As

Publication number Publication date
HUT47127A (en) 1989-01-30
EP0292023A3 (de) 1989-06-14
NO171065C (no) 1993-01-20
NZ224638A (en) 1990-04-26
GB8712115D0 (en) 1987-06-24
NO882233L (no) 1988-11-23
DK227388A (da) 1988-11-23
IL86394A0 (en) 1988-11-15
DK227388D0 (da) 1988-04-26
YU93288A (en) 1990-04-30
MX11493A (es) 1993-09-01
KR880013927A (ko) 1988-12-22
HU199868B (en) 1990-03-28
YU46860B (sh) 1994-06-24
FI882303A7 (fi) 1988-11-23
JPS63303992A (ja) 1988-12-12
ZA883447B (en) 1988-11-22
CN88103089A (zh) 1988-12-07
EP0292023A2 (de) 1988-11-23
IS3344A7 (is) 1988-11-23
PH26909A (en) 1992-12-03
DK165985C (da) 1993-11-08
FI882303A0 (fi) 1988-05-17
NO171065B (no) 1992-10-12
NO882233D0 (no) 1988-05-20
DK165985B (da) 1993-02-22
AU602083B2 (en) 1990-09-27
PT87550B (pt) 1992-09-30
AU1631788A (en) 1988-11-24
FI882303L (fi) 1988-11-23
MC1934A1 (fr) 1989-05-19

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920309

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930930