PT88636A - A process for the preparation of novel aminoalkyl-substituted heterocyclic sulfur compounds and of pharmaceutical compositionscontaining the same - Google Patents

A process for the preparation of novel aminoalkyl-substituted heterocyclic sulfur compounds and of pharmaceutical compositionscontaining the same

Info

Publication number
PT88636A
PT88636A PT88636A PT8863688A PT88636A PT 88636 A PT88636 A PT 88636A PT 88636 A PT88636 A PT 88636A PT 8863688 A PT8863688 A PT 8863688A PT 88636 A PT88636 A PT 88636A
Authority
PT
Portugal
Prior art keywords
substituted heterocyclic
sulfur compounds
preparation
same
heterocyclic sulfur
Prior art date
Application number
PT88636A
Other languages
English (en)
Other versions
PT88636B (pt
Inventor
Thomas M Bargar
Lawrence C Creemer
Robert J Broersma
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of PT88636A publication Critical patent/PT88636A/pt
Publication of PT88636B publication Critical patent/PT88636B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Detergent Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
PT88636A 1987-10-02 1988-09-30 Processo para a preparacao de novos compostos heterociclicos de enxofre aminoalquil-substituidos e de composicoes farmaceuticas que os contem PT88636B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/104,195 US4894389A (en) 1987-10-02 1987-10-02 Novel aminoalkyl-substituted heterocyclic sulfur compounds

Publications (2)

Publication Number Publication Date
PT88636A true PT88636A (pt) 1988-10-01
PT88636B PT88636B (pt) 1992-12-31

Family

ID=22299159

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88636A PT88636B (pt) 1987-10-02 1988-09-30 Processo para a preparacao de novos compostos heterociclicos de enxofre aminoalquil-substituidos e de composicoes farmaceuticas que os contem

Country Status (20)

Country Link
US (1) US4894389A (pt)
EP (1) EP0310109B1 (pt)
JP (1) JP2720177B2 (pt)
KR (1) KR970001490B1 (pt)
CN (1) CN1032792A (pt)
AT (1) ATE71374T1 (pt)
AU (1) AU606213B2 (pt)
CA (1) CA1329618C (pt)
DE (1) DE3867583D1 (pt)
DK (1) DK547088A (pt)
ES (1) ES2038264T3 (pt)
FI (1) FI884454A7 (pt)
GR (1) GR3003547T3 (pt)
HU (1) HU202221B (pt)
IL (1) IL87909A0 (pt)
NO (1) NO884367L (pt)
NZ (1) NZ226369A (pt)
PH (1) PH25378A (pt)
PT (1) PT88636B (pt)
ZA (1) ZA887235B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2001401A1 (en) * 1988-10-25 1990-04-25 Claude Piantadosi Quaternary amine containing ether or ester lipid derivatives and therapeutic compositions
US4970228A (en) * 1989-10-23 1990-11-13 Merrell Dow Pharmaceuticals Novel aminoalkyl-substituted heterocyclic sulfur compounds
EP0702556B1 (en) * 1993-06-10 2002-10-23 Wake Forest University (phospho)lipids for combatting hepatitis b virus infection
US7135584B2 (en) 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
AU3216695A (en) 1994-08-29 1996-03-22 University Of North Carolina At Chapel Hill, The Lipid analogs for treating viral infections
US7026469B2 (en) 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
US7309696B2 (en) 2000-10-19 2007-12-18 Wake Forest University Compositions and methods for targeting cancer cells
MXPA04001917A (es) 2001-08-31 2004-06-15 Thomson Licensing Sa Contador de secuencia para una corriente audio-visual.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839321A (en) * 1966-07-21 1974-10-01 Smithkline Corp 5-sulfamoyl-n-(2-substituted-ethyl) anthranilic acids
US3859308A (en) * 1973-05-07 1975-01-07 Velsicol Chemical Corp Heterocyclic anilids

Also Published As

Publication number Publication date
EP0310109B1 (en) 1992-01-08
EP0310109A2 (en) 1989-04-05
HUT50465A (en) 1990-02-28
DK547088D0 (da) 1988-09-30
NO884367L (no) 1989-04-03
CA1329618C (en) 1994-05-17
ZA887235B (en) 1989-05-30
US4894389A (en) 1990-01-16
GR3003547T3 (pt) 1993-03-16
KR890006614A (ko) 1989-06-13
ATE71374T1 (de) 1992-01-15
CN1032792A (zh) 1989-05-10
JP2720177B2 (ja) 1998-02-25
ES2038264T3 (es) 1993-07-16
DK547088A (da) 1989-04-03
AU606213B2 (en) 1991-01-31
DE3867583D1 (de) 1992-02-20
KR970001490B1 (ko) 1997-02-06
HU202221B (en) 1991-02-28
FI884454A7 (fi) 1989-04-03
EP0310109A3 (en) 1989-09-27
IL87909A0 (en) 1989-03-31
NZ226369A (en) 1990-09-26
PT88636B (pt) 1992-12-31
PH25378A (en) 1991-06-03
NO884367D0 (no) 1988-09-30
FI884454A0 (fi) 1988-09-28
AU2293688A (en) 1989-04-06
JPH01106880A (ja) 1989-04-24

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920616

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19941231