PT89227A - Processo para a preparacao de agentes anti-hipertensivos a base de mercapto-acilamino-acidos - Google Patents

Processo para a preparacao de agentes anti-hipertensivos a base de mercapto-acilamino-acidos

Info

Publication number
PT89227A
PT89227A PT89227A PT8922788A PT89227A PT 89227 A PT89227 A PT 89227A PT 89227 A PT89227 A PT 89227A PT 8922788 A PT8922788 A PT 8922788A PT 89227 A PT89227 A PT 89227A
Authority
PT
Portugal
Prior art keywords
mercapto
acylamino
acids
preparation
agents based
Prior art date
Application number
PT89227A
Other languages
English (en)
Other versions
PT89227B (pt
Inventor
Martin F Haslanger
Bernard R Neustadt
Elizabeth M Smith
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/133,669 external-priority patent/US5061710A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of PT89227A publication Critical patent/PT89227A/pt
Publication of PT89227B publication Critical patent/PT89227B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C07C327/04—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C327/06—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C07C327/16—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
PT89227A 1987-12-16 1988-12-15 Processo para a preparacao de agentes anti-hipertensivos a base de mercapto-acilamino-acidos PT89227B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/133,669 US5061710A (en) 1986-06-20 1987-12-16 Mercapto-acylamino acid antihypertensives

Publications (2)

Publication Number Publication Date
PT89227A true PT89227A (pt) 1989-12-29
PT89227B PT89227B (pt) 1993-07-30

Family

ID=22459750

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89227A PT89227B (pt) 1987-12-16 1988-12-15 Processo para a preparacao de agentes anti-hipertensivos a base de mercapto-acilamino-acidos

Country Status (18)

Country Link
EP (2) EP0390839A1 (pt)
JP (1) JPH02503799A (pt)
KR (1) KR940006770B1 (pt)
CN (1) CN1033803A (pt)
AT (1) ATE63741T1 (pt)
AU (1) AU615976B2 (pt)
DE (1) DE3862929D1 (pt)
DK (1) DK146890A (pt)
ES (1) ES2039578T3 (pt)
FI (1) FI903010A7 (pt)
GR (1) GR3002090T3 (pt)
HU (1) HU204781B (pt)
IL (1) IL88680A0 (pt)
NO (1) NO902687D0 (pt)
NZ (1) NZ227325A (pt)
PT (1) PT89227B (pt)
WO (1) WO1989005796A1 (pt)
ZA (1) ZA889373B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599951A (en) * 1989-09-15 1997-02-04 Societe Civile Bioprojet Amino acid derivatives, the process for their preparation and their applications to therapy
FR2652087B1 (fr) * 1989-09-15 1993-10-15 Bioprojet Ste Civile Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques.
EP0455833B1 (en) * 1989-11-27 1995-04-19 Santen Pharmaceutical Co., Ltd. Amino acid derivative
US5173506A (en) * 1990-08-16 1992-12-22 Schering Corporation N-(mercaptoalkyl)ureas and carbamates
US5244889A (en) * 1991-11-26 1993-09-14 Ciba-Geigy Corporation Certain macrocyclic lactam derivatives
US5872281A (en) * 1995-03-07 1999-02-16 Santen Pharmaceutical Co., Ltd. Amino acid derivative having N,N-dialkylaminophenyl group
EP0947502B1 (en) * 1996-09-05 2006-06-21 Santen Pharmaceutical Co., Ltd. Novel sulfur-containing amino acid derivatives
KR20160102210A (ko) 2013-12-27 2016-08-29 노버스 인터내쇼날 인코포레이티드 에톡시화 계면활성제
US10584306B2 (en) 2017-08-11 2020-03-10 Board Of Regents Of The University Of Oklahoma Surfactant microemulsions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173704A (en) * 1976-05-10 1979-11-06 E. R. Squibb & Sons, Inc. Dithio aminoacid derivatives
CH637374A5 (en) * 1977-12-02 1983-07-29 Squibb & Sons Inc Substituted amino acids
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4401677A (en) * 1981-10-09 1983-08-30 E. R. Squibb & Sons, Inc. Enkephalinase inhibitors
DE3243370A1 (de) * 1982-11-24 1984-05-24 Basf Ag, 6700 Ludwigshafen Benzoylthioverbindungen, ihre herstellung und verwendung als arzneimittel
US5036054A (en) * 1988-02-11 1991-07-30 Warner-Lambert Company Renin inhibitors containing alpha-heteroatom amino acids
AU4056389A (en) * 1988-08-24 1990-03-23 Schering Corporation Mercapto-acylamino acid antihypertensives
US4879309A (en) * 1988-09-27 1989-11-07 Schering Corporation Mercapto-acylamino acids as antihypertensives

Also Published As

Publication number Publication date
EP0322633A1 (en) 1989-07-05
NZ227325A (en) 1991-01-29
KR940006770B1 (ko) 1994-07-27
GR3002090T3 (en) 1992-12-30
EP0322633B1 (en) 1991-05-22
FI903010A0 (fi) 1990-06-15
DK146890D0 (da) 1990-06-15
DK146890A (da) 1990-06-15
ES2039578T3 (es) 1993-10-01
NO902687L (no) 1990-06-15
WO1989005796A1 (en) 1989-06-29
EP0390839A1 (en) 1990-10-10
HUT54979A (en) 1991-04-29
CN1033803A (zh) 1989-07-12
ZA889373B (en) 1990-08-29
AU2800289A (en) 1989-07-19
JPH02503799A (ja) 1990-11-08
HU890380D0 (en) 1991-03-28
NO902687D0 (no) 1990-06-15
PT89227B (pt) 1993-07-30
IL88680A0 (en) 1989-07-31
DE3862929D1 (de) 1991-06-27
HU204781B (en) 1992-02-28
ATE63741T1 (de) 1991-06-15
FI903010A7 (fi) 1990-06-15
AU615976B2 (en) 1991-10-17
KR900700443A (ko) 1990-08-13

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19930107

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940731