PT90813A - Processo de preparacao de derivados da fenotiazina e de composicoes farmaceuticas que os contem - Google Patents
Processo de preparacao de derivados da fenotiazina e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT90813A PT90813A PT90813A PT9081389A PT90813A PT 90813 A PT90813 A PT 90813A PT 90813 A PT90813 A PT 90813A PT 9081389 A PT9081389 A PT 9081389A PT 90813 A PT90813 A PT 90813A
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutical compositions
- preparation process
- compositions containing
- derivatives
- phenotiazine
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940066767 systemic antihistamines phenothiazine derivative Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
- C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8807770A FR2632520B1 (fr) | 1988-06-10 | 1988-06-10 | Derives de la phenothiazine analgesiques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT90813A true PT90813A (pt) | 1989-12-29 |
| PT90813B PT90813B (pt) | 1994-10-31 |
Family
ID=9367166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT90813A PT90813B (pt) | 1988-06-10 | 1989-06-09 | Processo de preparacao de derivados da fenotiazina e de composicoes farmaceuticas que os contem |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5049669A (pt) |
| EP (1) | EP0346238B1 (pt) |
| JP (1) | JP2504830B2 (pt) |
| KR (1) | KR0125575B1 (pt) |
| AT (1) | ATE90346T1 (pt) |
| AU (1) | AU621120B2 (pt) |
| CA (1) | CA1325631C (pt) |
| DE (1) | DE68906965T2 (pt) |
| DK (1) | DK283089A (pt) |
| ES (1) | ES2058569T3 (pt) |
| FR (1) | FR2632520B1 (pt) |
| HU (1) | HU205752B (pt) |
| IE (1) | IE63300B1 (pt) |
| IL (1) | IL90559A (pt) |
| MX (1) | MX9203585A (pt) |
| PT (1) | PT90813B (pt) |
| ZA (1) | ZA894397B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2632521B1 (fr) * | 1988-06-10 | 1990-09-14 | Rhone Poulenc Sante | Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2632522B1 (fr) * | 1988-06-10 | 1990-09-14 | Rhone Poulenc Sante | Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent |
| FR2652084B1 (fr) * | 1989-09-21 | 1991-10-31 | Rhone Poulenc Sante | Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2689013B1 (fr) * | 1992-03-30 | 1995-05-05 | Rhone Poulenc Rorer Sa | Nouvelle application thérapeutique des dérivés de la phénothiazine. |
| FR2720940A1 (fr) * | 1994-06-13 | 1995-12-15 | Rhone Poulenc Rorer Sa | Application du (+)-N-propyl [(pyrrolidinyl-1)-1 propyl-2]-10 phénothiazinecarboxamide comme antidépresseur. |
| CA2275167C (en) | 1996-12-16 | 2008-10-28 | Alcon Laboratories, Inc. | The topical use of kappa opioid agonists to treat ocular pain |
| US6174878B1 (en) | 1999-08-31 | 2001-01-16 | Alcon Laboratories, Inc. | Topical use of kappa opioid agonists to treat otic pain |
| WO2006070526A1 (ja) * | 2004-12-28 | 2006-07-06 | Murata Manufacturing Co., Ltd. | イオン発生ユニットおよびイオン発生装置 |
| KR101646962B1 (ko) | 2014-09-29 | 2016-08-10 | 한국과학기술연구원 | CaM 저해활성을 가지는 페노싸이아진 유도체 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2956996A (en) * | 1960-10-18 | Alkylated phenotfflazenecarboxamede | ||
| NL222355A (pt) * | 1957-11-05 | |||
| US3112310A (en) * | 1962-01-15 | 1963-11-26 | Searle & Co | 10-alkylaminoalkylphenothiazine-2-carboxamides |
| FR178F (fr) * | 1964-11-30 | Bruneau & Cie Lab | Médicament a base de dérivé d'acide phénothiazine carboxylique-3. | |
| FR2632521B1 (fr) * | 1988-06-10 | 1990-09-14 | Rhone Poulenc Sante | Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2632522B1 (fr) * | 1988-06-10 | 1990-09-14 | Rhone Poulenc Sante | Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent |
-
1988
- 1988-06-10 FR FR8807770A patent/FR2632520B1/fr not_active Expired - Lifetime
-
1989
- 1989-06-07 IL IL9055989A patent/IL90559A/en not_active IP Right Cessation
- 1989-06-09 DE DE89401601T patent/DE68906965T2/de not_active Expired - Fee Related
- 1989-06-09 ES ES89401601T patent/ES2058569T3/es not_active Expired - Lifetime
- 1989-06-09 PT PT90813A patent/PT90813B/pt not_active IP Right Cessation
- 1989-06-09 DK DK283089A patent/DK283089A/da not_active Application Discontinuation
- 1989-06-09 HU HU893033A patent/HU205752B/hu not_active IP Right Cessation
- 1989-06-09 EP EP89401601A patent/EP0346238B1/fr not_active Expired - Lifetime
- 1989-06-09 AT AT89401601T patent/ATE90346T1/de not_active IP Right Cessation
- 1989-06-09 AU AU36240/89A patent/AU621120B2/en not_active Ceased
- 1989-06-09 ZA ZA894397A patent/ZA894397B/xx unknown
- 1989-06-09 CA CA000602376A patent/CA1325631C/fr not_active Expired - Fee Related
- 1989-06-10 KR KR1019890008027A patent/KR0125575B1/ko not_active Expired - Fee Related
- 1989-06-12 JP JP1149261A patent/JP2504830B2/ja not_active Expired - Lifetime
- 1989-06-12 US US07/364,155 patent/US5049669A/en not_active Expired - Lifetime
- 1989-06-12 IE IE186589A patent/IE63300B1/en unknown
-
1992
- 1992-06-26 MX MX9203585A patent/MX9203585A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2058569T3 (es) | 1994-11-01 |
| IL90559A (en) | 1994-08-26 |
| EP0346238A1 (fr) | 1989-12-13 |
| ATE90346T1 (de) | 1993-06-15 |
| KR0125575B1 (ko) | 1998-07-01 |
| US5049669A (en) | 1991-09-17 |
| EP0346238B1 (fr) | 1993-06-09 |
| DE68906965D1 (de) | 1993-07-15 |
| FR2632520A1 (fr) | 1989-12-15 |
| HU205752B (en) | 1992-06-29 |
| JP2504830B2 (ja) | 1996-06-05 |
| KR910000680A (ko) | 1991-01-30 |
| DE68906965T2 (de) | 1993-12-09 |
| MX9203585A (es) | 1992-09-01 |
| FR2632520B1 (fr) | 1990-09-14 |
| JPH037269A (ja) | 1991-01-14 |
| IE891865L (en) | 1989-12-10 |
| CA1325631C (fr) | 1993-12-28 |
| ZA894397B (en) | 1990-02-28 |
| HUT50464A (en) | 1990-02-28 |
| PT90813B (pt) | 1994-10-31 |
| IE63300B1 (en) | 1995-04-05 |
| DK283089A (da) | 1989-12-11 |
| AU3624089A (en) | 1989-12-21 |
| AU621120B2 (en) | 1992-03-05 |
| IL90559A0 (en) | 1990-01-18 |
| DK283089D0 (da) | 1989-06-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940420 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20011031 |