PT91346A - Metodo para melhorar a memoria com r-n-(1-azabiciclo{2.2.2}oct-3-il) benzamidas e tiobenzamidas - Google Patents

Metodo para melhorar a memoria com r-n-(1-azabiciclo{2.2.2}oct-3-il) benzamidas e tiobenzamidas

Info

Publication number
PT91346A
PT91346A PT91346A PT9134689A PT91346A PT 91346 A PT91346 A PT 91346A PT 91346 A PT91346 A PT 91346A PT 9134689 A PT9134689 A PT 9134689A PT 91346 A PT91346 A PT 91346A
Authority
PT
Portugal
Prior art keywords
tiobenzamides
benzamides
azabicyclo
oct
improving memory
Prior art date
Application number
PT91346A
Other languages
English (en)
Other versions
PT91346B (pt
Inventor
Robert John Naylor
Brenda Naylor
Alain Renaud
Michel Langlois
Original Assignee
Robins Co Inc A H
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H, Delalande Sa filed Critical Robins Co Inc A H
Publication of PT91346A publication Critical patent/PT91346A/pt
Publication of PT91346B publication Critical patent/PT91346B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT91346A 1988-08-04 1989-08-02 Metodo para melhorar a memoria com r-n-(1-azabiciclo{2.2.2}oct-3-il) benzamidas e tiobenzamidas PT91346B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88402041A EP0353371A1 (en) 1988-08-04 1988-08-04 Memory enhancing-R-N-(1-azabicyclo[2.2.2] oct-3-yl) benzamides and thiobenzamides

Publications (2)

Publication Number Publication Date
PT91346A true PT91346A (pt) 1990-03-08
PT91346B PT91346B (pt) 1995-07-03

Family

ID=8200414

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91346A PT91346B (pt) 1988-08-04 1989-08-02 Metodo para melhorar a memoria com r-n-(1-azabiciclo{2.2.2}oct-3-il) benzamidas e tiobenzamidas

Country Status (10)

Country Link
US (1) US5017580A (pt)
EP (1) EP0353371A1 (pt)
JP (1) JPH02256616A (pt)
KR (1) KR900002778A (pt)
AU (1) AU624402B2 (pt)
CA (1) CA1333154C (pt)
DK (1) DK381889A (pt)
PH (1) PH25427A (pt)
PT (1) PT91346B (pt)
ZA (1) ZA895797B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3878235T2 (de) * 1988-08-04 1993-06-03 Synthelabo Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.)oct-3-yl)benzamide und thiobenzamide.
EP0527249B1 (en) * 1991-08-09 1997-12-17 Nec Corporation Carrier recovery apparatus for digital satellite communication system
US5273972A (en) * 1992-03-26 1993-12-28 A. H. Robins Company, Incorporated [(2-diakylaminomethyl)-3-quinuclidinyl]-benzamides and benzoates
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
US6492385B2 (en) 2000-08-18 2002-12-10 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
US6486172B2 (en) 2000-08-18 2002-11-26 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
US6479510B2 (en) 2000-08-18 2002-11-12 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
US6492386B2 (en) * 2000-08-18 2002-12-10 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
US6599916B2 (en) 2000-08-21 2003-07-29 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
WO2002017358A2 (en) 2000-08-21 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists)
PE20021019A1 (es) * 2001-04-19 2002-11-13 Upjohn Co Grupos azabiciclicos sustituidos
EP1419162A1 (en) * 2001-08-24 2004-05-19 Pharmacia & Upjohn Company Substituted-aryl 7-aza 2.2.1]bicycloheptanes for the treatment of disease
AU2002339810A1 (en) * 2001-10-16 2003-04-28 Astrazeneca Ab Azabicyclic compounds for the treatment of fibromyalgia syndrome
US6919359B2 (en) * 2001-11-08 2005-07-19 Pfizer Inc Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
US6852716B2 (en) 2002-02-15 2005-02-08 Pfizer Inc Substituted-aryl compounds for treatment of disease
CA2475773A1 (en) * 2002-02-20 2003-09-04 Pharmacia & Upjohn Company Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity
EP1542999A1 (en) 2002-08-01 2005-06-22 Pharmacia & Upjohn Company LLC 1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity
GB0310867D0 (en) 2003-05-12 2003-06-18 Novartis Ag Organic compounds
EP2344636B1 (en) 2008-10-09 2017-12-06 Howard Hughes Medical Institute Novel chimeric ligand-gated ion channels and methods of use thereof
KR20180011888A (ko) 2008-11-19 2018-02-02 포럼 파마슈티칼즈 인크. (ｒ)-７-클로로-ｎ-(퀴누클리딘-３-일)벤조［ｂ］티오펜-２-카르복사미드 및 그 약학적으로 허용가능한 염을 이용한 인지 장애의 치료
AR081402A1 (es) 2010-05-17 2012-08-29 Envivo Pharmaceuticals Inc Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il) benzo(b)tiofeno-2-carboxamida monohidrato
CA2872005A1 (en) 2012-05-08 2013-11-14 Forum Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function
CN104418851A (zh) * 2013-09-02 2015-03-18 上海龙翔生物医药开发有限公司 奎宁环衍生物的制备方法及纯化方法
JP6774658B2 (ja) * 2015-03-31 2020-10-28 有機合成薬品工業株式会社 潮解性を有さない３−アミノキヌクリジンの酸付加塩

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605652A (en) * 1985-02-04 1986-08-12 A. H. Robins Company, Inc. Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
DE3878235T2 (de) * 1988-08-04 1993-06-03 Synthelabo Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.)oct-3-yl)benzamide und thiobenzamide.

Also Published As

Publication number Publication date
DK381889A (da) 1990-02-05
JPH02256616A (ja) 1990-10-17
AU3917489A (en) 1990-02-08
DK381889D0 (da) 1989-08-03
PT91346B (pt) 1995-07-03
US5017580A (en) 1991-05-21
CA1333154C (en) 1994-11-22
PH25427A (en) 1991-07-01
KR900002778A (ko) 1990-03-23
EP0353371A1 (en) 1990-02-07
AU624402B2 (en) 1992-06-11
ZA895797B (en) 1991-03-27

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Legal Events

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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960731