PT91702A - Processo para a preparacao de novos nitratos organicos - Google Patents
Processo para a preparacao de novos nitratos organicosInfo
- Publication number
- PT91702A PT91702A PT91702A PT9170289A PT91702A PT 91702 A PT91702 A PT 91702A PT 91702 A PT91702 A PT 91702A PT 9170289 A PT9170289 A PT 9170289A PT 91702 A PT91702 A PT 91702A
- Authority
- PT
- Portugal
- Prior art keywords
- organic nitrates
- preparation
- acids
- tolerance
- new organic
- Prior art date
Links
- 229940082615 organic nitrates used in cardiac disease Drugs 0.000 title abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 229910002651 NO3 Inorganic materials 0.000 abstract 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- -1 sulphhydryl groups Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
- C07C327/34—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups with amino groups bound to the same hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3831311 | 1988-09-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT91702A true PT91702A (pt) | 1990-03-30 |
| PT91702B PT91702B (pt) | 1995-06-30 |
Family
ID=6362967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT91702A PT91702B (pt) | 1988-09-15 | 1989-09-13 | Processo para a preparacao de novos nitratos organicos |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0362575B1 (pt) |
| JP (1) | JP2628756B2 (pt) |
| AT (1) | ATE121077T1 (pt) |
| CZ (1) | CZ284586B6 (pt) |
| DE (1) | DE58909173D1 (pt) |
| DK (1) | DK452989A (pt) |
| ES (1) | ES2073418T3 (pt) |
| FI (1) | FI95569C (pt) |
| HR (1) | HRP920987A2 (pt) |
| HU (1) | HU209716B (pt) |
| IE (1) | IE65918B1 (pt) |
| PL (1) | PL163343B1 (pt) |
| PT (1) | PT91702B (pt) |
| SK (1) | SK530389A3 (pt) |
| YU (1) | YU48302B (pt) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4011505A1 (de) * | 1990-04-10 | 1991-10-24 | Sanol Arznei Schwarz Gmbh | Nitratoalkancarbonsaeure-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5284872A (en) * | 1989-09-12 | 1994-02-08 | Schwarz Pharma Ag | Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof |
| NL9001955A (nl) * | 1990-09-05 | 1992-04-01 | Cedona Pharm Bv | Nieuwe thiazolidinederivaten. |
| JP3361836B2 (ja) * | 1991-07-04 | 2003-01-07 | 三共株式会社 | アミノ酸誘導体 |
| FR2680173A1 (fr) * | 1991-08-07 | 1993-02-12 | Hoechst Lab | Nitrates organiques, leurs procedes de preparation et leur utilisation dans le traitement de maladies cardiovasculaires . |
| DE4321306A1 (de) * | 1993-06-26 | 1995-01-05 | Sanol Arznei Schwarz Gmbh | Disulfide |
| US5807847A (en) * | 1996-06-04 | 1998-09-15 | Queen's University At Kingston | Nitrate esters |
| ES2142773B1 (es) | 1998-10-07 | 2001-01-01 | Lacer Sa | Derivados de mononitrato de isosorbida y su empleo como agentes vasodilatadores con tolerancia desminuida. |
| US20100099729A1 (en) | 2007-02-05 | 2010-04-22 | Nicox S.A. | Nitric oxide donor compounds |
| EP2149576A1 (en) | 2008-07-22 | 2010-02-03 | Lacer, S.A. | Isosorbide Nitrates having vasodilating activity |
| CN103739499B (zh) | 2011-10-24 | 2016-09-07 | 尼科斯科学爱尔兰公司 | 醌基一氧化氮供体化合物 |
| WO2014169976A1 (en) | 2013-04-18 | 2014-10-23 | Nicox Science Ireland | Quinone based nitric oxide donating compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3512627A1 (de) * | 1985-04-06 | 1986-10-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel |
-
1989
- 1989-07-25 JP JP1192477A patent/JP2628756B2/ja not_active Expired - Lifetime
- 1989-09-09 AT AT89116700T patent/ATE121077T1/de active
- 1989-09-09 DE DE58909173T patent/DE58909173D1/de not_active Expired - Fee Related
- 1989-09-09 EP EP89116700A patent/EP0362575B1/de not_active Expired - Lifetime
- 1989-09-09 ES ES89116700T patent/ES2073418T3/es not_active Expired - Lifetime
- 1989-09-12 YU YU176289A patent/YU48302B/sh unknown
- 1989-09-13 PT PT91702A patent/PT91702B/pt unknown
- 1989-09-13 IE IE293289A patent/IE65918B1/en not_active IP Right Cessation
- 1989-09-14 CZ CS895303A patent/CZ284586B6/cs not_active IP Right Cessation
- 1989-09-14 DK DK452989A patent/DK452989A/da not_active Application Discontinuation
- 1989-09-14 SK SK5303-89A patent/SK530389A3/sk unknown
- 1989-09-14 PL PL89281420A patent/PL163343B1/pl unknown
- 1989-09-14 FI FI894350A patent/FI95569C/fi not_active IP Right Cessation
- 1989-09-14 HU HU894831A patent/HU209716B/hu not_active IP Right Cessation
-
1992
- 1992-10-02 HR HRP920987AA patent/HRP920987A2/hr not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4011505A1 (de) * | 1990-04-10 | 1991-10-24 | Sanol Arznei Schwarz Gmbh | Nitratoalkancarbonsaeure-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE121077T1 (de) | 1995-04-15 |
| PT91702B (pt) | 1995-06-30 |
| FI95569B (fi) | 1995-11-15 |
| HRP920987A2 (hr) | 1994-04-30 |
| EP0362575B1 (de) | 1995-04-12 |
| IE65918B1 (en) | 1995-11-29 |
| HU209716B (en) | 1994-10-28 |
| PL163343B1 (pl) | 1994-03-31 |
| DK452989D0 (da) | 1989-09-14 |
| IE892932L (en) | 1990-03-15 |
| FI894350A0 (fi) | 1989-09-14 |
| JP2628756B2 (ja) | 1997-07-09 |
| JPH0291054A (ja) | 1990-03-30 |
| YU176289A (en) | 1992-02-20 |
| CZ530389A3 (cs) | 1998-11-11 |
| HUT51229A (en) | 1990-04-28 |
| SK280513B6 (sk) | 2000-03-13 |
| CZ284586B6 (cs) | 1999-01-13 |
| YU48302B (sh) | 1998-05-15 |
| ES2073418T3 (es) | 1995-08-16 |
| FI95569C (fi) | 1996-02-26 |
| EP0362575A1 (de) | 1990-04-11 |
| SK530389A3 (en) | 2000-03-13 |
| DK452989A (da) | 1990-03-16 |
| DE58909173D1 (de) | 1995-05-18 |
| FI894350L (fi) | 1990-03-16 |
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