PT927043E - Composições para transferência de um gene para o sistema nervoso central - Google Patents

Composições para transferência de um gene para o sistema nervoso central Download PDF

Info

Publication number: PT927043E
Authority: PT; Portugal
Prior art keywords: cells; cell; tumoricidal; matrix according; susceptibility
Prior art date: 1996-04-08

Application number

PT97920192T

Other languages

English (en)

Portuguese (pt)

Inventor

Bruce Cherskey

Louis R Bucalo

Original Assignee

Univ New York

Titan Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-08

Filing date

1997-04-07

Publication date

2007-03-30

1997-04-07 Application filed by Univ New York, Titan Pharmaceuticals Inc filed Critical Univ New York

2007-03-30 Publication of PT927043E publication Critical patent/PT927043E/pt

Links

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230000026731 phosphorylation Effects 0.000 description 1
238000006366 phosphorylation reaction Methods 0.000 description 1
108700004029 pol Genes Proteins 0.000 description 1
101150088264 pol gene Proteins 0.000 description 1
229920002492 poly(sulfone) Polymers 0.000 description 1
229920002401 polyacrylamide Polymers 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
229920002635 polyurethane Polymers 0.000 description 1
239000004814 polyurethane Substances 0.000 description 1
229920002451 polyvinyl alcohol Polymers 0.000 description 1
229920002981 polyvinylidene fluoride Polymers 0.000 description 1
239000011148 porous material Substances 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
230000002035 prolonged effect Effects 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
210000002637 putamen Anatomy 0.000 description 1
230000006798 recombination Effects 0.000 description 1
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238000009877 rendering Methods 0.000 description 1
230000004044 response Effects 0.000 description 1
210000002955 secretory cell Anatomy 0.000 description 1
239000012679 serum free medium Substances 0.000 description 1
LIVNPJMFVYWSIS-UHFFFAOYSA-N silicon monoxide Chemical class [Si-]#[O+] LIVNPJMFVYWSIS-UHFFFAOYSA-N 0.000 description 1
239000011734 sodium Substances 0.000 description 1
239000000243 solution Substances 0.000 description 1
238000012453 sprague-dawley rat model Methods 0.000 description 1
230000000638 stimulation Effects 0.000 description 1
238000003860 storage Methods 0.000 description 1
239000000758 substrate Substances 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
239000006228 supernatant Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
229960002180 tetracycline Drugs 0.000 description 1
229930101283 tetracycline Natural products 0.000 description 1
235000019364 tetracycline Nutrition 0.000 description 1
150000003522 tetracyclines Chemical class 0.000 description 1
238000003146 transient transfection Methods 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

PT97920192T 1996-04-08 1997-04-07 Composições para transferência de um gene para o sistema nervoso central PT927043E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/629,308 US6210664B1 (en)	1996-04-08	1996-04-08	Method for gene transfer to the central nervous system

Publications (1)

Publication Number	Publication Date
PT927043E true PT927043E (pt)	2007-03-30

Family

ID=24522456

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97920192T PT927043E (pt)	1996-04-08	1997-04-07	Composições para transferência de um gene para o sistema nervoso central

Country Status (13)

Country	Link
US (2)	US6210664B1 (da)
EP (1)	EP0927043B8 (da)
JP (2)	JP2000508641A (da)
AT (1)	ATE347903T1 (da)
AU (1)	AU724537C (da)
CA (1)	CA2251232C (da)
DE (1)	DE69737101T2 (da)
DK (1)	DK0927043T3 (da)
ES (1)	ES2277356T3 (da)
PT (1)	PT927043E (da)
TW (1)	TWI222870B (da)
WO (1)	WO1997037684A1 (da)
ZA (1)	ZA972971B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6210664B1 (en) *	1996-04-08	2001-04-03	New York University Medical Center	Method for gene transfer to the central nervous system
CA2647246C (en) *	2006-03-30	2015-06-23	Research Foundation Of City University Of New York	Stimulation of neuron regeneration by secretory leukocyte protease inhibitor
KR20260007295A (ko)	2018-05-24	2026-01-13	셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨	거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치
MX2020012459A (es)	2018-05-24	2021-04-28	Celanese Eva Performance Polymers Llc	Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular.
EP3803866A4 (en)	2018-05-24	2022-03-16	Nureva Inc.	METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS
BR112023022439A2 (pt)	2021-04-26	2023-12-26	Celanese Eva Performance Polymers Llc	Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE117375T1 (de) *	1987-09-11	1995-02-15	Whitehead Biomedical Inst	Transduktionsveränderte fibroblasten und ihre anwendung.
US5650148A (en) *	1988-12-15	1997-07-22	The Regents Of The University Of California	Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system
DE69133205T2 (de) *	1990-10-19	2003-12-11	New York University, New York	Eine methode zur transplantation von zellen in das gehirn und ihre therapeutische verwendung
US5618531A (en) *	1990-10-19	1997-04-08	New York University	Method for increasing the viability of cells which are administered to the brain or spinal cord
US5529774A (en) *	1991-08-13	1996-06-25	The Regents Of The University Of California	In vivo transfer of the HSV-TK gene implanted retroviral producer cells
AU3586993A (en) *	1992-01-23	1993-09-01	New York University	A method for transplanting cells into the brain and therapeutic uses therefor
AU688321B2 (en) *	1993-04-21	1998-03-12	Institut Pasteur	Biocompatible implant for the expression and secretion in vivo of a therapeutic compound
SG48813A1 (en) *	1993-08-12	1998-05-18	Cytotherapeutics Inc	Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US5688773A (en) *	1994-08-17	1997-11-18	The General Hospital Corporation	Method of selectively destroying neoplastic cells
US6210664B1 (en) *	1996-04-08	2001-04-03	New York University Medical Center	Method for gene transfer to the central nervous system

1996
- 1996-04-08 US US08/629,308 patent/US6210664B1/en not_active Expired - Fee Related
1997
- 1997-04-07 PT PT97920192T patent/PT927043E/pt unknown
- 1997-04-07 AU AU24449/97A patent/AU724537C/en not_active Ceased
- 1997-04-07 CA CA002251232A patent/CA2251232C/en not_active Expired - Fee Related
- 1997-04-07 JP JP9536418A patent/JP2000508641A/ja not_active Withdrawn
- 1997-04-07 ES ES97920192T patent/ES2277356T3/es not_active Expired - Lifetime
- 1997-04-07 DK DK97920192T patent/DK0927043T3/da active
- 1997-04-07 EP EP97920192A patent/EP0927043B8/en not_active Expired - Lifetime
- 1997-04-07 WO PCT/US1997/005746 patent/WO1997037684A1/en not_active Ceased
- 1997-04-07 AT AT97920192T patent/ATE347903T1/de not_active IP Right Cessation
- 1997-04-07 DE DE69737101T patent/DE69737101T2/de not_active Expired - Fee Related
- 1997-04-08 ZA ZA9702971A patent/ZA972971B/xx unknown
- 1997-04-09 TW TW086104516A patent/TWI222870B/zh not_active IP Right Cessation
2000
- 2000-12-04 US US09/730,328 patent/US6565845B2/en not_active Expired - Fee Related
2004
- 2004-08-11 JP JP2004234879A patent/JP2004337176A/ja active Pending

Also Published As

Publication number	Publication date
DK0927043T3 (da)	2007-04-10
CA2251232A1 (en)	1997-10-16
EP0927043A4 (en)	2004-09-01
WO1997037684A1 (en)	1997-10-16
ZA972971B (en)	1997-11-03
ATE347903T1 (de)	2007-01-15
JP2000508641A (ja)	2000-07-11
US20010003585A1 (en)	2001-06-14
JP2004337176A (ja)	2004-12-02
AU724537B2 (en)	2000-09-21
AU724537C (en)	2001-07-19
AU2444997A (en)	1997-10-29
CA2251232C (en)	2005-10-25
EP0927043B8 (en)	2007-04-18
TWI222870B (en)	2004-11-01
EP0927043A1 (en)	1999-07-07
DE69737101D1 (de)	2007-01-25
HK1021801A1 (en)	2000-07-07
US6210664B1 (en)	2001-04-03
US6565845B2 (en)	2003-05-20
DE69737101T2 (de)	2007-05-31
EP0927043B1 (en)	2006-12-13
ES2277356T3 (es)	2007-07-01

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ES2237089T3 (es)	2005-07-16	Usos para celulas madre mesenquimatosas humanas no autologas.
US7033744B2 (en)	2006-04-25	Method for proliferating a liver cell, a liver cell obtained thereby, and use thereof
EP0906124B1 (en)	2003-07-30	Device and method for encapsulated gene therapy
ES2356814T3 (es)	2011-04-13	Proceso para producir linfocitos citotóxicos.
UA65525C2 (en)	2004-04-15	Capsules containing encapsulated cells, method for their preparation
PT927043E (pt)	2007-03-30	Composições para transferência de um gene para o sistema nervoso central
AU765149B2 (en)	2003-09-11	Method for gene transfer to the central nervous system
Kobayashi et al.	2001	A reversibly immortalized human hepatocyte cell line as a source of hepatocyte‐based biological support
HK1021801B (en)	2007-05-11	Composition for gene transfer to the central nervous system
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