PT93671A - Processo para a preparacao de derivados de hidroxi-alquil-furanilo e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados de hidroxi-alquil-furanilo e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT93671A PT93671A PT93671A PT9367190A PT93671A PT 93671 A PT93671 A PT 93671A PT 93671 A PT93671 A PT 93671A PT 9367190 A PT9367190 A PT 9367190A PT 93671 A PT93671 A PT 93671A
- Authority
- PT
- Portugal
- Prior art keywords
- 6alkyl
- pharmaceutical compositions
- hydrogen
- compositions containing
- alkyl
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 1
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 1
- -1 C1-6alkyloxycarbonyl Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Furan Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33502289A | 1989-04-07 | 1989-04-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT93671A true PT93671A (pt) | 1990-11-20 |
| PT93671B PT93671B (pt) | 1996-06-28 |
Family
ID=23309914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT93671A PT93671B (pt) | 1989-04-07 | 1990-04-05 | Processo para a preparacao de derivados de hidroxi-alquil-furanilo e de composicoes farmaceuticas que os contem |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0393738B1 (pt) |
| JP (1) | JPH02290874A (pt) |
| KR (1) | KR900016193A (pt) |
| CN (1) | CN1031403C (pt) |
| AT (1) | ATE114653T1 (pt) |
| AU (1) | AU615612B2 (pt) |
| CA (1) | CA2013892A1 (pt) |
| DE (1) | DE69014385T2 (pt) |
| DK (1) | DK0393738T3 (pt) |
| ES (1) | ES2067645T3 (pt) |
| FI (1) | FI95702C (pt) |
| GR (1) | GR3015154T3 (pt) |
| HU (1) | HUT58324A (pt) |
| IE (1) | IE65460B1 (pt) |
| IL (1) | IL94008A (pt) |
| NO (1) | NO174851C (pt) |
| NZ (1) | NZ233088A (pt) |
| PH (1) | PH30434A (pt) |
| PT (1) | PT93671B (pt) |
| RU (1) | RU2030415C1 (pt) |
| ZA (1) | ZA902664B (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2043564A1 (en) * | 1990-07-06 | 1992-01-07 | Alfons G. M. De Knaep | 3-[(5-methyl-2-furanyl)methyl]-n-(4-piperidinyl)-3h-imidazo [4,5-b]-pyridin-2-amine 2-hydroxy-1,2,3-propanetricarboxylate |
| FR2668150B1 (fr) * | 1990-10-17 | 1994-11-18 | Theramex | Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant. |
| DK0599968T3 (da) * | 1991-08-14 | 2000-04-17 | Procter & Gamble Pharma | Oxazolidinonderivater, der er egnede som antiarytmi- og antifibrilleringsmidler |
| AU3258293A (en) * | 1992-01-09 | 1993-08-03 | Janssen Pharmaceutica N.V. | Antihistaminic piperazinyl derivatives |
| US5521183A (en) * | 1994-08-30 | 1996-05-28 | Allergan | Use of 5-HT ligands as anti-pruritic agents |
| ES2150671T3 (es) * | 1995-04-21 | 2000-12-01 | Neurosearch As | Compuesto de bencimidazol y su utilizacion como moduladores del complejo de receptores gaba-a. |
| CA2218493C (en) * | 1995-04-21 | 2005-02-22 | Neurosearch A/S | Benzimidazole compounds and their use as modulators of the gabaa receptor complex |
| BR9916371A (pt) * | 1998-12-19 | 2001-09-18 | Janssen Pharmaceutica Nv | Composto de espiro anti-histamìnico |
| ES2165274B1 (es) * | 1999-06-04 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
| EP1418175A1 (en) * | 1999-06-28 | 2004-05-12 | Janssen Pharmaceutica N.V. | Respiratory syncytial virus replication inhibitors |
| EP3233799B1 (en) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
| EP3233077B1 (en) | 2014-12-19 | 2026-05-06 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4556660A (en) * | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
| US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
| PH23995A (en) * | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
| US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
| US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
| GB8515934D0 (en) * | 1985-06-24 | 1985-07-24 | Janssen Pharmaceutica Nv | (4-piperidinomethyl and-hetero)purines |
| ES2052544T3 (es) * | 1986-02-03 | 1994-07-16 | Janssen Pharmaceutica Nv | Composiciones anti-histaminicas que contienen n-heterociclil-4-piperidinaminas. |
| US4897401A (en) * | 1987-06-19 | 1990-01-30 | Janssen Pharmaceutical N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases |
| CA1317939C (en) * | 1987-07-01 | 1993-05-18 | Janssen Pharmaceutica Naamloze Vennootschap | ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines |
-
1990
- 1990-03-09 PH PH40171A patent/PH30434A/en unknown
- 1990-03-26 NZ NZ233088A patent/NZ233088A/xx unknown
- 1990-03-27 EP EP90200720A patent/EP0393738B1/en not_active Expired - Lifetime
- 1990-03-27 AT AT90200720T patent/ATE114653T1/de not_active IP Right Cessation
- 1990-03-27 DE DE69014385T patent/DE69014385T2/de not_active Expired - Fee Related
- 1990-03-27 DK DK90200720.2T patent/DK0393738T3/da active
- 1990-03-27 ES ES90200720T patent/ES2067645T3/es not_active Expired - Lifetime
- 1990-04-05 CA CA002013892A patent/CA2013892A1/en not_active Abandoned
- 1990-04-05 PT PT93671A patent/PT93671B/pt not_active IP Right Cessation
- 1990-04-05 IL IL9400890A patent/IL94008A/xx not_active IP Right Cessation
- 1990-04-05 ZA ZA902664A patent/ZA902664B/xx unknown
- 1990-04-05 AU AU52951/90A patent/AU615612B2/en not_active Ceased
- 1990-04-06 JP JP2090528A patent/JPH02290874A/ja active Pending
- 1990-04-06 FI FI901755A patent/FI95702C/fi not_active IP Right Cessation
- 1990-04-06 NO NO901580A patent/NO174851C/no unknown
- 1990-04-06 RU SU904743517A patent/RU2030415C1/ru active
- 1990-04-06 IE IE125790A patent/IE65460B1/en not_active IP Right Cessation
- 1990-04-06 KR KR1019900004737A patent/KR900016193A/ko not_active Ceased
- 1990-04-06 HU HU902107A patent/HUT58324A/hu unknown
- 1990-04-07 CN CN90101997A patent/CN1031403C/zh not_active Expired - Fee Related
-
1995
- 1995-02-22 GR GR950400374T patent/GR3015154T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1031403C (zh) | 1996-03-27 |
| JPH02290874A (ja) | 1990-11-30 |
| CN1046161A (zh) | 1990-10-17 |
| ATE114653T1 (de) | 1994-12-15 |
| PH30434A (en) | 1997-05-09 |
| DK0393738T3 (da) | 1995-01-16 |
| NO174851C (no) | 1994-07-20 |
| RU2030415C1 (ru) | 1995-03-10 |
| NZ233088A (en) | 1991-10-25 |
| CA2013892A1 (en) | 1990-10-07 |
| HUT58324A (en) | 1992-02-28 |
| GR3015154T3 (en) | 1995-05-31 |
| FI901755A0 (fi) | 1990-04-06 |
| NO901580L (no) | 1990-10-08 |
| AU5295190A (en) | 1990-10-11 |
| EP0393738B1 (en) | 1994-11-30 |
| NO901580D0 (no) | 1990-04-06 |
| DE69014385D1 (de) | 1995-01-12 |
| ZA902664B (en) | 1991-12-24 |
| PT93671B (pt) | 1996-06-28 |
| IL94008A0 (en) | 1991-01-31 |
| FI95702B (fi) | 1995-11-30 |
| HU902107D0 (en) | 1990-07-28 |
| KR900016193A (ko) | 1990-11-12 |
| IL94008A (en) | 1997-02-18 |
| EP0393738A1 (en) | 1990-10-24 |
| IE901257L (en) | 1990-10-07 |
| AU615612B2 (en) | 1991-10-03 |
| ES2067645T3 (es) | 1995-04-01 |
| FI95702C (fi) | 1996-03-11 |
| DE69014385T2 (de) | 1995-04-20 |
| IE65460B1 (en) | 1995-11-01 |
| NO174851B (no) | 1994-04-11 |
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| Publication | Publication Date | Title |
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| PT87939A (pt) | Processo para a preparacao de 2-(heterociclilalquil)imidazopiridinas e de composicoes farmaceuticas que as contem | |
| AU622509B2 (en) | 2-aminopyrimidinone derivatives | |
| ES2052686T3 (es) | Un procedimiento para preparar nuevos derivados de bencimidazol sustituidos. | |
| ATE114653T1 (de) | Hydroxyalkylfuranyl-derivate. | |
| AU3945589A (en) | Substituted 4-piperidinyl-indol-5-yl-alkyl-sulphonamide derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19960325 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19980930 |