PT93673A - Processo para a preparacao de derivados da piridina - Google Patents

Processo para a preparacao de derivados da piridina

Info

Publication number: PT93673A
Authority: PT; Portugal
Prior art keywords: pyridine derivatives; preparation; formula; agonists; antihypertensives
Prior art date: 1989-04-07

Application number

PT93673A

Other languages

English (en)

Other versions

PT93673B (pt

Inventor

Alan Chapman White

Richard S Todd

Ian Anthony Cliffe

Howard Langham Mansell

Original Assignee

Wyeth John & Brother Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-07

Filing date

1990-04-05

Publication date

1990-11-20

1990-04-05 Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd

1990-11-20 Publication of PT93673A publication Critical patent/PT93673A/pt

1996-08-30 Publication of PT93673B publication Critical patent/PT93673B/pt

Links

JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical class C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 abstract 1
101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 abstract 1
208000019901 Anxiety disease Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
208000022531 anorexia Diseases 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
230000036506 anxiety Effects 0.000 abstract 1
208000015114 central nervous system disease Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
206010061428 decreased appetite Diseases 0.000 abstract 1
-1 heteroaromatic N-oxides Chemical class 0.000 abstract 1
239000004031 partial agonist Substances 0.000 abstract 1
150000003222 pyridines Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PT93673A 1989-04-07 1990-04-05 Processo para a preparacao de derivados da piridina PT93673B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898907865A GB8907865D0 (en)	1989-04-07	1989-04-07	Tetrahydroquinoline derivatives

Publications (2)

Publication Number	Publication Date
PT93673A true PT93673A (pt)	1990-11-20
PT93673B PT93673B (pt)	1996-08-30

Family

ID=10654625

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT93673A PT93673B (pt)	1989-04-07	1990-04-05	Processo para a preparacao de derivados da piridina

Country Status (22)

Country	Link
US (1)	US5075303A (pt)
EP (1)	EP0395244B1 (pt)
JP (1)	JP2945064B2 (pt)
KR (1)	KR0156569B1 (pt)
AT (1)	ATE149031T1 (pt)
AU (1)	AU625845B2 (pt)
CA (1)	CA2014062C (pt)
DD (1)	DD298391A5 (pt)
DE (1)	DE69029954T2 (pt)
DK (1)	DK0395244T3 (pt)
ES (1)	ES2099703T3 (pt)
FI (1)	FI95373C (pt)
GB (2)	GB8907865D0 (pt)
GR (1)	GR3023396T3 (pt)
HK (1)	HK121994A (pt)
HU (1)	HU217128B (pt)
IE (1)	IE63627B1 (pt)
IL (1)	IL94011A (pt)
NZ (1)	NZ233222A (pt)
PH (1)	PH27590A (pt)
PT (1)	PT93673B (pt)
ZA (1)	ZA902662B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2660657B1 (fr) *	1990-04-09	1993-05-07	Adir	Nouveaux derives du 3-aminochromane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5273994A (en) *	1990-04-09	1993-12-28	Adir Et Compagnie	3-aminochroman compounds
GB9019942D0 (en) *	1990-09-12	1990-10-24	Wyeth John & Brother Ltd	Azetidine derivatives
US5532243A (en) *	1992-02-14	1996-07-02	The Dupont Merck Pharmaceutical Company	Antipsychotic nitrogen-containing bicyclic compounds
GB9304632D0 (en) *	1993-03-06	1993-04-21	Wyeth John & Brother Ltd	Amide derivatives
JPH09510695A (ja) *	1994-01-03	1997-10-28	エイシア・ファーマシュウティカルズ，インコーポレイテッド	８−アザ、６−アザ、および６，８−ジアザ−１，４−ジヒドロキノキサリン−２，３−ジオン類およびそのグリシン／ｎｍｄａリセプターに対するアンタゴニストとしての使用
US5609849A (en) *	1994-03-11	1997-03-11	The Trustees Of The University Of Pennsylvania	Serotonin (5-HT1A) receptor ligands and imaging agents
US6180632B1 (en) *	1997-05-28	2001-01-30	Aventis Pharmaceuticals Products Inc.	Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
US7105513B2 (en) *	2002-08-07	2006-09-12	Sanofi-Avertis Deutschland Gmbh	Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals
KR20110130487A (ko) *	2009-03-23	2011-12-05	시플라 리미티드	독사조신 및 그의 염의 제조방법
LT2772484T (lt) *	2011-10-18	2017-12-27	Astellas Pharma Inc.	Biciklinis heterociklinis junginys
WO2015153813A1 (en) *	2014-04-01	2015-10-08	Howard Hughes Medical Institute	Azetidine-substituted fluorescent compounds
US12440581B2 (en)	2019-09-19	2025-10-14	Howard Hughes Medical Institute	Fluorophores for super-resolution imaging

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH566315A5 (pt) *	1972-04-04	1975-09-15	Ciba Geigy Ag
GB1463583A (en) *	1974-03-05	1977-02-02	Wyeth John & Brother Ltd	Halo and hydroxy compounds
GB1463582A (en) *	1974-03-05	1977-02-02	Wyeth John & Brother Ltd	Pyridine derivatives
FI68821C (fi) *	1977-07-18	1985-11-11	Sandoz Ag	Analogifoerfarande foer framstaellning av nya tetralinderivat vilka saenker blodtryck och oekar blodetsgenomstroemning
SE8004002L (sv) *	1980-05-29	1981-11-30	Arvidsson Folke Lars Erik	Terapeutiskt anvendbara tetralinderivat
US4748182A (en) *	1986-03-05	1988-05-31	Merrell Dow Pharmaceuticals Inc.	Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents
DK111387A (da) *	1986-03-05	1987-09-06	Otsuka Pharma Co Ltd	Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
JPS63107990A (ja) *	1986-05-14	1988-05-12	Nippon Shinyaku Co Ltd	キノリンカルボン酸誘導体
DE3718317A1 (de) *	1986-12-10	1988-06-16	Bayer Ag	Substituierte basische 2-aminotetraline
DE3719924A1 (de) *	1986-12-22	1988-06-30	Bayer Ag	8-substituierte 2-aminotetraline
US4894084A (en) *	1987-12-29	1990-01-16	Fmc Corporation	Substituted quinolinonyl and dihydroquinolinonyl triazolinone herbicides
US4878941A (en) *	1987-12-29	1989-11-07	Fmc Corporation	Herbicides

1989
- 1989-04-07 GB GB898907865A patent/GB8907865D0/en active Pending
1990
- 1990-04-05 ZA ZA902662A patent/ZA902662B/xx unknown
- 1990-04-05 PT PT93673A patent/PT93673B/pt not_active IP Right Cessation
- 1990-04-05 IL IL9401190A patent/IL94011A/en not_active IP Right Cessation
- 1990-04-05 NZ NZ233222A patent/NZ233222A/en unknown
- 1990-04-05 AU AU52971/90A patent/AU625845B2/en not_active Ceased
- 1990-04-06 US US07/505,957 patent/US5075303A/en not_active Expired - Lifetime
- 1990-04-06 CA CA002014062A patent/CA2014062C/en not_active Expired - Fee Related
- 1990-04-06 GB GB9007889A patent/GB2230007B/en not_active Expired - Fee Related
- 1990-04-06 HU HU902108A patent/HU217128B/hu not_active IP Right Cessation
- 1990-04-06 KR KR1019900004697A patent/KR0156569B1/ko not_active Expired - Fee Related
- 1990-04-06 DE DE69029954T patent/DE69029954T2/de not_active Expired - Fee Related
- 1990-04-06 DK DK90303708.3T patent/DK0395244T3/da active
- 1990-04-06 ES ES90303708T patent/ES2099703T3/es not_active Expired - Lifetime
- 1990-04-06 FI FI901761A patent/FI95373C/fi not_active IP Right Cessation
- 1990-04-06 DD DD90339534A patent/DD298391A5/de unknown
- 1990-04-06 JP JP2092961A patent/JP2945064B2/ja not_active Expired - Fee Related
- 1990-04-06 AT AT90303708T patent/ATE149031T1/de not_active IP Right Cessation
- 1990-04-06 PH PH40345A patent/PH27590A/en unknown
- 1990-04-06 EP EP90303708A patent/EP0395244B1/en not_active Expired - Lifetime
- 1990-04-06 IE IE125290A patent/IE63627B1/en not_active IP Right Cessation
1994
- 1994-11-03 HK HK121994A patent/HK121994A/xx not_active IP Right Cessation
1997
- 1997-05-09 GR GR970401050T patent/GR3023396T3/el unknown

Also Published As

Publication number	Publication date
GB2230007A (en)	1990-10-10
HUT54658A (en)	1991-03-28
GR3023396T3 (en)	1997-08-29
JPH02290852A (ja)	1990-11-30
DE69029954T2 (de)	1997-05-28
DD298391A5 (de)	1992-02-20
EP0395244B1 (en)	1997-02-19
KR900016138A (ko)	1990-11-12
PH27590A (en)	1993-08-18
HU217128B (hu)	1999-11-29
GB9007889D0 (en)	1990-06-06
DK0395244T3 (da)	1997-03-17
ATE149031T1 (de)	1997-03-15
HU902108D0 (en)	1990-08-28
AU5297190A (en)	1990-10-11
HK121994A (en)	1994-11-11
CA2014062A1 (en)	1990-10-07
IL94011A (en)	1994-06-24
FI901761A0 (fi)	1990-04-06
GB2230007B (en)	1992-10-14
FI95373B (fi)	1995-10-13
US5075303A (en)	1991-12-24
PT93673B (pt)	1996-08-30
DE69029954D1 (de)	1997-03-27
ES2099703T3 (es)	1997-06-01
JP2945064B2 (ja)	1999-09-06
CA2014062C (en)	2000-06-13
KR0156569B1 (ko)	1998-11-16
NZ233222A (en)	1991-07-26
FI95373C (fi)	1996-01-25
EP0395244A1 (en)	1990-10-31
GB8907865D0 (en)	1989-05-24
ZA902662B (en)	1991-02-27
IE63627B1 (en)	1995-05-17
AU625845B2 (en)	1992-07-16

Legal Events

Date

Code

Title

Description

1996-08-30

FG3A

Patent granted, date of granting

Effective date: 19960513

2004-02-27

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20031130

Publication	Publication Date	Title
MA21778A1 (fr)	1990-10-01	Procede d'obtention de derives de n - ( 3-hydroxy-4 piperidinyl ) dihydro-benzofuranne, dihydro-2h- ,benzopyranne ou dihydro benzodioxin ) carboxamide .
ES2130116T3 (es)	1999-07-01	Derivados de piperazina.
BR8704582A (pt)	1988-04-26	Processo para preparar derivados de piridinacarboxamida
PH24199A (en)	1990-04-10	Derivatives of quinoline carboxylic acid,pharmaceutical composition containing same and process of preparing same
GB2230007B (en)	1992-10-14	Pyridine derivatives
NO178969C (no)	1996-07-10	Analogifremgangsmåte for fremstilling av terapeutisk aktive, substituerte kinazolinoner
PT92234A (pt)	1990-05-31	Processo para a preparacao de 1,2,3,4-tetraidro-1,9-acridinodiaminas
NO930284L (no)	1993-08-02	Pyridinderivater, fremgangsmaate for deres fremstilling oganvendelse derav
DK0405442T3 (da)	1996-09-23	4,5-Dihydro-6H-imidazo 4,5,1-ij quinolin-6-on-6-oxim-O-sulfonsyrederivater
MX9100345A (es)	1992-02-28	Procedimiento para la preparacion de derivados 6-(aminopropionil sustituidos)de forscolina
ES2056873T3 (es)	1994-10-16	Derivados de 1-acil-2,3-dihidro-4-(1h)-quinolinona-4-oxima, procedimiento para producirlos y uso de los mismos.
ES8802506A1 (es)	1988-07-16	Procedimiento para preparar derivados de fluoralcanos.
ATE112284T1 (de)	1994-10-15	Exo-3'-4'-o-benzyliden-3''-demethylchartreusin und seine salze.
ATE45356T1 (de)	1989-08-15	Pyridinderivate.