PT946730E - Mutantes de toxina estreptococica c e metodos de utilizacao - Google Patents

Mutantes de toxina estreptococica c e metodos de utilizacao

Info

Publication number
PT946730E
PT946730E PT97949733T PT97949733T PT946730E PT 946730 E PT946730 E PT 946730E PT 97949733 T PT97949733 T PT 97949733T PT 97949733 T PT97949733 T PT 97949733T PT 946730 E PT946730 E PT 946730E
Authority
PT
Portugal
Prior art keywords
spe
methods
toxin
vaccine
toxins
Prior art date
Application number
PT97949733T
Other languages
English (en)
Portuguese (pt)
Inventor
Patrick M Schlievert
Ohlendorf Douglas
David T Mitchell
Pamala J Gahr
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of PT946730E publication Critical patent/PT946730E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/832—Drug, bio-affecting and body treating compositions involving bacterial toxin that has modified amino acid sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT97949733T 1996-12-06 1997-12-05 Mutantes de toxina estreptococica c e metodos de utilizacao PT946730E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3325196P 1996-12-06 1996-12-06

Publications (1)

Publication Number Publication Date
PT946730E true PT946730E (pt) 2006-06-30

Family

ID=21869358

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97949733T PT946730E (pt) 1996-12-06 1997-12-05 Mutantes de toxina estreptococica c e metodos de utilizacao

Country Status (14)

Country Link
US (1) US6835818B2 (fr)
EP (1) EP0946730B1 (fr)
JP (1) JP2002513278A (fr)
KR (1) KR100615836B1 (fr)
CN (1) CN1148449C (fr)
AT (1) ATE319830T1 (fr)
AU (1) AU734597B2 (fr)
BR (1) BR9713679A (fr)
CA (1) CA2273824C (fr)
DE (1) DE69735439T2 (fr)
DK (1) DK0946730T3 (fr)
ES (1) ES2260804T3 (fr)
PT (1) PT946730E (fr)
WO (1) WO1998024910A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW517061B (en) * 1996-03-29 2003-01-11 Pharmacia & Amp Upjohn Ab Modified/chimeric superantigens and their use
US7087235B2 (en) * 1997-06-25 2006-08-08 The United States Of America As Represented By The Secretary Of The Army Fusion protein of streptococcal pyrogenic exotoxins
US6872394B1 (en) 1997-12-02 2005-03-29 Idaho Research Foundation, Inc. Non-toxic immune stimulating enterotoxin compositions
US7491402B2 (en) 1998-12-24 2009-02-17 Auckland Uniservices Limited Superantigens SMEZ-2, SPE-G, SPE-H and SPE-J and uses thereof
JP2004515479A (ja) * 2000-12-04 2004-05-27 オークランド ユニサーヴィスィズ リミテッド 免疫調節性構築物およびその使用
SE0102327D0 (sv) * 2001-06-28 2001-06-28 Active Biotech Ab A novel engineered superantigen for human therapy
GB0227026D0 (en) * 2002-11-20 2002-12-24 Molecular Skincare Ltd Psoriasis diagnostics and therapeutics
US7299231B2 (en) * 2004-07-29 2007-11-20 International Business Machines Corporation Method and system of subsetting a cluster of servers
AU2017206656B2 (en) 2016-01-10 2024-02-01 Neotx Therapeutics Ltd. Immunopotentiator enhanced superantigen mediated cancer immunotherapy
EP3806896A4 (fr) * 2018-05-16 2022-06-29 Griffith University Syndrome de choc toxique streptococcique
AU2020275142A1 (en) 2019-05-15 2021-12-16 Neotx Therapeutics Ltd. Cancer treatment
IL296103A (en) 2020-03-05 2022-11-01 Neotx Therapeutics Ltd Methods and compositions for treating cancer with immune cells
US20260058877A1 (en) * 2024-08-23 2026-02-26 Microsoft Technology Licensing, Llc Determining network topology information from domain name system (dns) queries

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784948A (en) 1983-08-10 1988-11-15 The Rockefeller University Production of streptococcal m protein immunogens and molecular probes
US5298396A (en) * 1989-11-15 1994-03-29 National Jewish Center For Immunology And Respiratory Medicine Method for identifying T cells disease involved in autoimmune disease
US5336598A (en) * 1989-11-15 1994-08-09 National Jewish Center For Immunology And Respiratory Medicine Method for diagnosing a superantigen caused pathologial condition via assay of T-cells
WO1993014634A1 (fr) 1992-01-28 1993-08-05 National Jewish Center For Immunology And Respiratory Medicine Effets protecteurs de superantigenes ayant subi une mutation
US5460813A (en) * 1993-04-05 1995-10-24 National Jewish Center For Immunology And Respiratory Medicine Method for treating Kawasaki syndrome by administration of an anti-TSST-1 agent which is not gamma globulin
JPH11514844A (ja) 1995-06-07 1999-12-21 リージェンツ オブ ザ ユニバーシティー オブ ミネソタ 連鎖球菌毒素ａの突然変異体および使用方法

Also Published As

Publication number Publication date
CN1148449C (zh) 2004-05-05
KR20000069337A (ko) 2000-11-25
ES2260804T3 (es) 2006-11-01
EP0946730A2 (fr) 1999-10-06
CA2273824A1 (fr) 1998-06-11
US6835818B2 (en) 2004-12-28
DE69735439D1 (de) 2006-05-04
BR9713679A (pt) 2001-07-17
DE69735439T2 (de) 2006-09-07
AU7625698A (en) 1998-06-29
WO1998024910A2 (fr) 1998-06-11
AU734597B2 (en) 2001-06-21
EP0946730B1 (fr) 2006-03-08
WO1998024910A3 (fr) 1998-09-03
JP2002513278A (ja) 2002-05-08
CN1240001A (zh) 1999-12-29
ATE319830T1 (de) 2006-03-15
CA2273824C (fr) 2007-05-08
HK1024265A1 (en) 2000-10-05
DK0946730T3 (da) 2006-07-10
US20020039585A1 (en) 2002-04-04
KR100615836B1 (ko) 2006-08-25

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