PT982035E - Composicao de ciclosporina compreendendo um veiculo hidrofilo - Google Patents

Composicao de ciclosporina compreendendo um veiculo hidrofilo

Info

Publication number
PT982035E
PT982035E PT98306607T PT98306607T PT982035E PT 982035 E PT982035 E PT 982035E PT 98306607 T PT98306607 T PT 98306607T PT 98306607 T PT98306607 T PT 98306607T PT 982035 E PT982035 E PT 982035E
Authority
PT
Portugal
Prior art keywords
propylene glycol
composition
hydrofil
cyclosporine
composing
Prior art date
Application number
PT98306607T
Other languages
English (en)
Inventor
Amarjit Singh
Rajesh Jain
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Publication of PT982035E publication Critical patent/PT982035E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT98306607T 1998-08-18 1998-08-18 Composicao de ciclosporina compreendendo um veiculo hidrofilo PT982035E (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
RU98115892/14A RU2178293C2 (ru) 1998-08-18 1998-08-18 Фармацевтическая композиция, содержащая циклоспорин, способ получения мягких желатиновых капсул
EP98306607A EP0982035B1 (en) 1998-08-18 1998-08-18 Cyclosporin composition comprising an hydrophilic carrier
CNB981185851A CN1199642C (zh) 1998-08-18 1998-09-04 含环孢菌素的新型药物组合物
CA002249675A CA2249675A1 (en) 1998-08-18 1998-10-06 A novel composition containing cyclosporin

Publications (1)

Publication Number Publication Date
PT982035E true PT982035E (pt) 2004-08-31

Family

ID=31999277

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98306607T PT982035E (pt) 1998-08-18 1998-08-18 Composicao de ciclosporina compreendendo um veiculo hidrofilo

Country Status (9)

Country Link
EP (2) EP0982035B1 (pt)
CN (1) CN1199642C (pt)
AT (1) ATE262916T1 (pt)
CA (1) CA2249675A1 (pt)
DE (2) DE69822814T2 (pt)
DK (1) DK0982035T3 (pt)
ES (1) ES2215277T3 (pt)
PT (1) PT982035E (pt)
RU (1) RU2178293C2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2354233A1 (en) * 1998-12-11 2000-06-15 Pharmasolutions, Inc. Self-emulsifying compositions for drugs poorly soluble in water
WO2001030379A2 (en) 1999-10-27 2001-05-03 Alexandra Lucas Compositions and methods for preventing and treating transplant rejection
GB2362573A (en) * 2000-05-25 2001-11-28 Cipla Ltd Cyclosporin formulation
ATE290876T1 (de) * 2000-05-04 2005-04-15 Panacea Biotec Ltd Pharmazeutische zusammensetzung enthaltend cyclosprin als aktiven bestandteil
MXPA02004900A (es) 2000-09-18 2003-10-24 Rpg Life Sciences Ltd Formulacion autoemulsificable, con mejores actividades de bioabsorcion e inmunosupresion.
JP2004509171A (ja) 2000-09-29 2004-03-25 ゾーン、 ロバート ズィー. 炎症及び免疫反応の治療方法及びその組成物
RU2207870C2 (ru) * 2000-11-10 2003-07-10 Панацея Биотек Лимитед Фармацевтическая композиция, включающая циклоспорин в качестве активного ингредиента
EP2116228A1 (en) 2001-10-19 2009-11-11 Isotechnika Inc. Novel cyclosporin analog microemulsion preconcentrates
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
RU2285511C2 (ru) * 2004-10-13 2006-10-20 НИИ ГБ им. Гельмгольца Средство для лечения синдрома сухого глаза
US7285530B2 (en) 2004-10-21 2007-10-23 Viron Therapeutics, Inc. Use of SERP-1 as an antiplatelet agent
BRPI0616476A2 (pt) * 2005-09-30 2011-06-21 Scynexis Inc uso de uma quantidade terapeuticamente eficaz de um derivado de ciclosporina, e, composição farmacêutica
US20090130198A1 (en) * 2007-11-21 2009-05-21 Innopharmax Inc. Pharmaceutical composition with enhanced bioavailability
CN104427976B (zh) * 2012-05-10 2018-04-24 佩因拉佛姆有限公司 疏水的活性成分的储库制剂及其制备方法
CN103301068B (zh) * 2013-07-08 2014-09-10 广东彼迪药业有限公司 一种头孢克肟干混悬剂剂及其制备方法
CN103462914B (zh) * 2013-09-04 2015-12-09 南京正宽医药科技有限公司 一种头孢克肟片剂及其制备方法
CN111789943B (zh) * 2019-04-08 2024-01-19 洛阳赛威生物科技有限公司 一种水包油佐剂组合物及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
ES2308955T5 (es) * 1993-09-28 2012-04-03 R.P. Scherer Gmbh Fabricación de cápsulas de gelatina blanda
IT1277338B1 (it) * 1995-07-25 1997-11-10 Poli Ind Chimicia S P A Composizioni farmaceutiche di ciclosporina o altre sostanze peptidiche
KR20050084502A (ko) * 1997-01-30 2005-08-26 노파르티스 아게 오일을 함유하지 않은 사이클로스포린 a 함유 제약 조성물

Also Published As

Publication number Publication date
DE69921409T2 (de) 2006-03-09
EP0985412A3 (en) 2001-05-02
EP0982035B1 (en) 2004-03-31
EP0982035A1 (en) 2000-03-01
DE69921409D1 (de) 2004-12-02
DE69822814T2 (de) 2005-01-27
CN1199642C (zh) 2005-05-04
ES2215277T3 (es) 2004-10-01
DE69822814D1 (de) 2004-05-06
CA2249675A1 (en) 2000-04-06
EP0985412B1 (en) 2004-10-27
DK0982035T3 (da) 2004-06-28
CN1247060A (zh) 2000-03-15
ATE262916T1 (de) 2004-04-15
EP0985412A2 (en) 2000-03-15
RU2178293C2 (ru) 2002-01-20

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