PT98563A - Processo para a preparacao de composicoes farmaceuticas contendo hormona do crescimento humano factor de libertacao da hormona do crescimento humano factor do crescimento semelhante a insulina humano ou os seus analogos e/ou misturas para o tratamento da deficiencia de lactogenese humana - Google Patents

Processo para a preparacao de composicoes farmaceuticas contendo hormona do crescimento humano factor de libertacao da hormona do crescimento humano factor do crescimento semelhante a insulina humano ou os seus analogos e/ou misturas para o tratamento da deficiencia de lactogenese humana

Info

Publication number: PT98563A
Authority: PT; Portugal
Prior art keywords: human; growth hormone; treatment; factor; compounds
Prior art date: 1990-08-03

Application number

PT98563A

Other languages

English (en)

Other versions

PT98563B (pt

Inventor

Peter Gluckman

Stella Ruth Milsom

Original Assignee

Kabi Pharmacia Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-03

Filing date

1991-08-02

Publication date

1992-06-30

1991-08-02 Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab

1992-06-30 Publication of PT98563A publication Critical patent/PT98563A/pt

1999-01-29 Publication of PT98563B publication Critical patent/PT98563B/pt

Links

230000006651 lactation Effects 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 3
102000018997 Growth Hormone Human genes 0.000 title 1
108010051696 Growth Hormone Proteins 0.000 title 1
101000976075 Homo sapiens Insulin Proteins 0.000 title 1
101000825742 Homo sapiens Somatoliberin Proteins 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
230000007812 deficiency Effects 0.000 title 1
239000000122 growth hormone Substances 0.000 title 1
230000010005 growth-factor like effect Effects 0.000 title 1
PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
239000000203 mixture Substances 0.000 abstract 3
239000003623 enhancer Substances 0.000 abstract 2
230000000009 lactational effect Effects 0.000 abstract 2
238000004519 manufacturing process Methods 0.000 abstract 2
102000002265 Human Growth Hormone Human genes 0.000 abstract 1
108010000521 Human Growth Hormone Proteins 0.000 abstract 1
239000000854 Human Growth Hormone Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Endocrinology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Molecular Biology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Reproductive Health (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)
Processing Of Solid Wastes (AREA)
Treatment Of Sludge (AREA)
Separation Of Suspended Particles By Flocculating Agents (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Dairy Products (AREA)

PT98563A 1990-08-03 1991-08-02 Processo para a preparacao de composicoes farmaceuticas contendo hormona do crescimento humano factor de libertacao da hormona do crescimento humano factor do crescimento semelhante a insulina humano ou os seus analogos e/ou misturas para o tratamento da deficiencia de lactogenese humana PT98563B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NZ23476690		1990-08-03

Publications (2)

Publication Number	Publication Date
PT98563A true PT98563A (pt)	1992-06-30
PT98563B PT98563B (pt)	1999-01-29

Family

ID=19923318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98563A PT98563B (pt)	1990-08-03	1991-08-02	Processo para a preparacao de composicoes farmaceuticas contendo hormona do crescimento humano factor de libertacao da hormona do crescimento humano factor do crescimento semelhante a insulina humano ou os seus analogos e/ou misturas para o tratamento da deficiencia de lactogenese humana

Country Status (13)

Country	Link
US (1)	US5276014A (pt)
EP (1)	EP0652767B1 (pt)
JP (1)	JP3074302B2 (pt)
AT (1)	ATE184489T1 (pt)
AU (1)	AU643073B2 (pt)
CA (1)	CA2086754C (pt)
DE (1)	DE69131629T2 (pt)
DK (1)	DK0652767T3 (pt)
ES (1)	ES2138960T3 (pt)
GR (1)	GR3032156T3 (pt)
IE (1)	IE912345A1 (pt)
PT (1)	PT98563B (pt)
WO (1)	WO1992002245A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ260309A (en) *	1992-06-08	1997-07-27	Pharmacia Ab Substituted For K	Use of 1gf-2 for prevention or treatment of nutritional or gastrointestinal disorders and promoting neonatal growth
KR960705808A (ko) *	1993-11-09	1996-11-08	조셉 에프. 디프리마	성장 호르몬의 방출을 촉진시키는 피페리딘, 피롤리딘 및 헥사하이드로-1H-아제핀(Piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone)
WO1996009065A1 (en) *	1994-09-21	1996-03-28	Pharmacia & Upjohn Ab	Method of treating hypertension in pregnant mammals
WO1996019235A1 (en) *	1994-12-21	1996-06-27	Auckland Uniservices Limited	Enhancement of fetal growth by administration of insulin-like growth factor-1(igf-1)
GR1007178B (el) *	1995-02-22	2011-01-31	Πετρομανωλακης Εμμ.	Πρωραιος αγωγος σκαφους με διατομην αεροτομης.
US5622932A (en) *	1995-05-05	1997-04-22	Eli Lilly And Company	IGF-1 superagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3853833A (en) *	1971-04-27	1974-12-10	Hormone Res Foundation	Synthetic human growth-promoting and lactogenic hormones and method of producing same
BG49718A3 (bg) *	1983-07-15	1992-01-15	Bio- Technology General Corp	Метод за получаване на полипептид със супероксиддисмутазна активност
EP0193917A3 (en) *	1985-03-06	1987-09-23	American Cyanamid Company	Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration
DK382886A (da) *	1985-08-12	1987-02-13	Syntex Inc	Fremgangsmaade til fremstilling af hormonfaktorderivater
US4783524A (en) *	1985-09-17	1988-11-08	Monsanto Company	Growth factors
CA1299103C (en) *	1986-03-07	1992-04-21	Robert Joseph Collier	Method and compositions for increasing mammary parenchyma
IL86102A (en) *	1987-05-11	1994-04-12	Univ Tulane	Alkylated growth hormone-releasing peptides and use thereof
FR2622455B1 (fr) *	1987-11-04	1991-07-12	Agronomique Inst Nat Rech	Application du facteur de stimulation de la secretion de l'hormone de croissance humaine, de ses fragments actifs et des analogues correspondants, pour augmenter la production laitiere et le poids des nouveau-nes chez les mammiferes
US5089473A (en) *	1988-08-29	1992-02-18	Monsanto Company	Somatotropin variants and their use

1991
- 1991-07-04 IE IE234591A patent/IE912345A1/en not_active IP Right Cessation
- 1991-07-19 DE DE69131629T patent/DE69131629T2/de not_active Expired - Fee Related
- 1991-07-19 CA CA002086754A patent/CA2086754C/en not_active Expired - Fee Related
- 1991-07-19 AU AU85108/91A patent/AU643073B2/en not_active Ceased
- 1991-07-19 DK DK91916584T patent/DK0652767T3/da active
- 1991-07-19 JP JP03515025A patent/JP3074302B2/ja not_active Expired - Fee Related
- 1991-07-19 WO PCT/SE1991/000503 patent/WO1992002245A1/en not_active Ceased
- 1991-07-19 EP EP91916584A patent/EP0652767B1/en not_active Expired - Lifetime
- 1991-07-19 AT AT91916584T patent/ATE184489T1/de not_active IP Right Cessation
- 1991-07-19 ES ES91916584T patent/ES2138960T3/es not_active Expired - Lifetime
- 1991-08-02 PT PT98563A patent/PT98563B/pt not_active IP Right Cessation
- 1991-09-26 US US07/765,171 patent/US5276014A/en not_active Expired - Fee Related
1999
- 1999-12-15 GR GR990403242T patent/GR3032156T3/el unknown

Also Published As

Publication number	Publication date
DE69131629T2 (de)	2000-03-09
EP0652767B1 (en)	1999-09-15
WO1992002245A1 (en)	1992-02-20
ES2138960T3 (es)	2000-02-01
AU8510891A (en)	1992-03-02
DE69131629D1 (de)	1999-10-21
IE912345A1 (en)	1992-02-12
AU643073B2 (en)	1993-11-04
DK0652767T3 (da)	2000-04-03
PT98563B (pt)	1999-01-29
JPH05509329A (ja)	1993-12-22
EP0652767A1 (en)	1995-05-17
JP3074302B2 (ja)	2000-08-07
ATE184489T1 (de)	1999-10-15
US5276014A (en)	1994-01-04
GR3032156T3 (en)	2000-04-27
CA2086754A1 (en)	1992-02-04
CA2086754C (en)	2000-08-29

Legal Events

Date	Code	Title	Description
1992-06-30	BB1A	Laying open of patent application	Effective date: 19920219
1999-01-29	FG3A	Patent granted, date of granting	Effective date: 19981020
2006-06-30	MM3A	Annulment or lapse	Effective date: 20060420

Publication	Publication Date	Title
ATE204178T1 (de)	2001-09-15	Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin
BR9813373A (pt)	2000-10-03	Composto, processo para a preparação do mesmo, composição farmacêutica, processo para a preparação da mesma, uso de um composto, e, processos para efetuar imunossupressão e para tratar ou reduzir o risco de uma doença das vias aérias obstrutiva reversìvel em um paciente
PT88985A (pt)	1988-12-01	Processo para a preparacao de composicoes farmaceuticas nasais e ou oftalmicas contendo azelastina
DK642587A (da)	1987-12-08	Insulinpraeparat
ATE112684T1 (de)	1994-10-15	Verwendung von igf-ii zur behandlung von knochenkrankheiten.
MY109309A (en)	1997-01-31	Improvements in or relating to somatostatins
EP0914107A1 (en)	1999-05-12	Compositions comprising lidocaine and emu oil and methods of use thereof
ATE56365T1 (de)	1990-09-15	Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung.
FI886019A7 (fi)	1988-12-28	Laastari vaikuttavien aineiden valvotusti jakamiseksi iholle
PT98563A (pt)	1992-06-30	Processo para a preparacao de composicoes farmaceuticas contendo hormona do crescimento humano factor de libertacao da hormona do crescimento humano factor do crescimento semelhante a insulina humano ou os seus analogos e/ou misturas para o tratamento da deficiencia de lactogenese humana
SE8204874L (sv)	1983-02-28	Farmaceutiska preparat, innefattande humant insulin och humant proinsulin
HUT57204A (en)	1991-11-28	Process for producing 4-fluoro-2-///4-methoxy-2-pyridinyl/-methyl/-sulfinyl/-1h-benzimidazol with gastric acid secration-diminishing activity and pharmaceutical compositions containing them
DK527186A (da)	1987-05-07	Bronchodilaterende farmaceutisk praeparat
ZA873928B (en)	1988-02-24	Topical methotrexate preparation for the treatment of hyperproliferative epithelial disease
BRPI0411536A (pt)	2006-08-01	compostos, formulação farmacêutica, método para tratar ou prevenir distúrbios de lipìdeo (dislipidemia) associados ou não com resistência à insulina, uso de composto, método para tratar ou prevenir diabetes de tipo 2, composição farmacêutica, e, processo para preparar um composto
DE3276786D1 (en)	1987-08-27	Medical process and preparation
GR3001565T3 (en)	1992-11-23	Medical preparation comprising aspoxicillin, a method for its preparation, and the use of such a preparation for the manufacture of a medicament
SE8401409D0 (sv)	1984-03-14	New pharmaceutical preparations and a new method of alleviation of pain
GB2280370A (en)	1995-02-01	Pharmaceutical composition for the treatment of chronic skin ulcers