PT99770A - Processo para a preparacao de receptores de glutamato acoplados com proteina g de mamiferos - Google Patents

Processo para a preparacao de receptores de glutamato acoplados com proteina g de mamiferos

Info

Publication number
PT99770A
PT99770A PT99770A PT9977091A PT99770A PT 99770 A PT99770 A PT 99770A PT 99770 A PT99770 A PT 99770A PT 9977091 A PT9977091 A PT 9977091A PT 99770 A PT99770 A PT 99770A
Authority
PT
Portugal
Prior art keywords
protein
mammals
preparation
glutamate receptors
receptors
Prior art date
Application number
PT99770A
Other languages
English (en)
Other versions
PT99770B (pt
Inventor
Eileen Ranae Mulvihill
Frederick Stamner Hagen
Khaled M Houamed
Wolfhard Almers
Original Assignee
Univ Washington
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27417405&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT99770(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Washington, Zymogenetics Inc filed Critical Univ Washington
Publication of PT99770A publication Critical patent/PT99770A/pt
Publication of PT99770B publication Critical patent/PT99770B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/286—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PT99770A 1990-12-12 1991-12-11 Processo para a preparacao de receptores de glutamato acoplados com proteina g de mamiferos PT99770B (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62680690A 1990-12-12 1990-12-12
US64848191A 1991-01-30 1991-01-30
US67200791A 1991-03-18 1991-03-18

Publications (2)

Publication Number Publication Date
PT99770A true PT99770A (pt) 1992-12-31
PT99770B PT99770B (pt) 1999-05-31

Family

ID=27417405

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99770A PT99770B (pt) 1990-12-12 1991-12-11 Processo para a preparacao de receptores de glutamato acoplados com proteina g de mamiferos

Country Status (12)

Country Link
US (2) US5747267A (pt)
EP (1) EP0577605B1 (pt)
JP (1) JPH06503961A (pt)
AT (1) ATE203566T1 (pt)
AU (1) AU9135691A (pt)
CA (1) CA2098295C (pt)
DE (1) DE69132671T2 (pt)
IE (1) IE914314A1 (pt)
IL (1) IL100343A (pt)
NZ (1) NZ240921A (pt)
PT (1) PT99770B (pt)
WO (1) WO1992010583A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0548165T3 (da) 1990-09-13 2001-07-16 Univ Duke Ekspression af G-proteinkoblede receptorer i gær
US6190864B1 (en) * 1991-05-08 2001-02-20 Chiron Corporation HCV genomic sequences for diagnostics and therapeutics
IL105587A0 (en) * 1992-05-08 1993-09-22 Lilly Co Eli Human metabotropic glutamate receptor and related dna compounds
CA2101586A1 (en) 1992-08-05 1994-02-06 Rajender Kamboj Ampa-binding human glur4 receptors
CA2105804C (en) 1992-09-17 2003-04-29 Rajender Kamboj Kainate-binding, human cns receptors of the eaa5 family
US5521297A (en) * 1993-06-04 1996-05-28 Salk Institute Biotechnology/Industrial Associates Nucleic acids encoding human metabotropic glutamate receptors
US5728545A (en) * 1993-06-18 1998-03-17 The Salk Institute Of Biological Studies Cloning and recombinant production of CRF receptor (S)
AU695641B2 (en) 1993-09-20 1998-08-20 Novartis Ag Human metabotropic glutamate receptor subtypes (HMR4, HMR6, HMR7) and related DNA compounds
US6274330B1 (en) 1993-12-30 2001-08-14 Zymogenetics, Inc. L-AP4 sensitive glutamate receptors
WO1995022609A2 (en) * 1994-02-21 1995-08-24 The Wellcome Foundation Limited Human glutamate receptor proteins
DE4410882A1 (de) * 1994-03-29 1995-10-05 Basf Ag Verfahren zur permanenten Expression von Glutamatrezeptoren
US5527703A (en) * 1994-05-25 1996-06-18 Merck & Co., Inc. DNA encoding glutamate gated chloride channels
US5693492A (en) * 1995-05-05 1997-12-02 Merck & Co., Inc. DNA encoding glutamate gated chloride channels
ES2308779T3 (es) 1995-07-26 2008-12-01 Astrazeneca Ab Receptores quimericos y metodos para identificar compuestos activos en los receptores de glutamato metabotropico y el uso de tales compuestos en el tratamiento de trastornos y enfermedades neurologicas.
US6084084A (en) * 1996-02-21 2000-07-04 Nps Pharmaceuticals, Inc. Human metabotropic glutamate receptor
DE19801646A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte alpha,beta-annellierte Butyrolactone
DE19801636A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte bicyclische Lactone
DE19801647A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte beta,gamma-annellierte Lactone
US7262280B1 (en) 1998-04-03 2007-08-28 Nps Pharmaceuticals, Inc. G-protein fusion receptors and constructs encoding same
AU4820399A (en) * 1998-06-29 2000-01-17 Hyseq, Inc. A chemokine receptor obtained from a cdna library of fetal liver-spleen
JP2002523056A (ja) * 1998-08-18 2002-07-30 ザ ジョンズ ホプキンス ユニバーシティー スクール オブ メディシン Ｈｏｍｅｒ相互作用タンパク質
EP1662255A3 (en) * 1998-08-18 2006-09-13 The Johns Hopkins University School Of Medicine Homer interacting proteins
GB9826359D0 (en) * 1998-12-01 1999-01-27 Glaxo Group Ltd Novel receptors
EP2348047A1 (en) * 2000-04-21 2011-07-27 New England Medical Center G protein coupled receptor (GPCR) agonists and antagonists and methods of activating and inhibiting GPCR using the same
US7696168B2 (en) * 2000-04-21 2010-04-13 Tufts Medical Center, Inc. G protein coupled receptor agonists and antagonists and methods of activating and inhibiting G protein coupled receptors using the same
US20030151980A1 (en) * 2002-02-13 2003-08-14 Isador Farash Color referenced multi-time watch
AU2003211958A1 (en) 2002-02-14 2003-09-04 Ajinomoto Co., Inc. Novel glutamate receptor and utilization thereof
WO2005075987A2 (en) * 2004-01-28 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human metabotropic glutamate receptor 1 (mglur1)
US7271257B2 (en) * 2004-08-20 2007-09-18 Ajinomoto Co., Inc. Glutamate receptors and utilization thereof
JP2008519039A (ja) * 2004-11-04 2008-06-05 ニュー イングランド メデカル センター ホスピタルズ インク Ｇタンパク質共役型受容体アゴニストおよびアンタゴニストならびに使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859609A (en) * 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5385831A (en) * 1990-12-12 1995-01-31 Zymogenetics, Inc. Method for producing a mammalian G protein coupled glutamate receptor
JP3353841B2 (ja) * 1992-11-13 2002-12-03 三菱化学株式会社 新規なタンパク質およびそれをコードする遺伝子
IL105587A0 (en) * 1992-05-08 1993-09-22 Lilly Co Eli Human metabotropic glutamate receptor and related dna compounds

Also Published As

Publication number Publication date
ATE203566T1 (de) 2001-08-15
EP0577605B1 (en) 2001-07-25
CA2098295A1 (en) 1992-06-13
EP0577605A4 (pt) 1994-04-13
DE69132671D1 (de) 2001-08-30
AU9135691A (en) 1992-07-08
CA2098295C (en) 2003-04-22
EP0577605A1 (en) 1994-01-12
IE914314A1 (en) 1992-06-17
US5721107A (en) 1998-02-24
US5747267A (en) 1998-05-05
JPH06503961A (ja) 1994-05-12
IL100343A (en) 2001-09-13
IL100343A0 (en) 1992-09-06
NZ240921A (en) 1994-06-27
DE69132671T2 (de) 2002-07-04
PT99770B (pt) 1999-05-31
WO1992010583A1 (en) 1992-06-25

Similar Documents

Publication Publication Date Title
PT99770A (pt) Processo para a preparacao de receptores de glutamato acoplados com proteina g de mamiferos
ATE142645T1 (de) Rezeptoren für wachstumshormone
DE68918867D1 (de) Mutanten des hiv-1 Hüllproteins mit fehlenden hypervariabelen domänen.
Breckler et al. Isolation of a new high molecular weight protein associated with desmin and vimentin filaments from avian embryonic skeletal muscle
DE69233421D1 (de) Neuartige rezeptor-typ tyrosinkinase und deren verwendung
DK0673420T3 (da) Mammale receptorer for interleukin 10 (IL-10)
BR9814335A (pt) Proteìna, exceto as existentes ao natural, polinucleotìdeo substancialmente puro, anticorpo elaborado por um processo que compreende a etapa de injetar uma preparação farmaceuticamente aceitável, vetor para expressar o drr-1 de rato, vetor, célula hospedeira drr-1 de rato, drr-1 de ser humano, drr-2 de ser humano, drr-3 de ser humano, drr-4 de ser humano, drr-5 de ser humano, drr-6 de ser humano recombinantes, e, processo para ensaiar um composto de teste quanto à sua capacidade para ligar-se a ou para ativar um receptor especìfico de gânglios da raiz dorsal ligado à proteìna g (drr)
NO20003716L (no) Protein D for anvendelse in vitro, renset antistoff som binder proteinet, samt anvendelser derav
BR9507618A (pt) Frações polipeptidicas solúveis da proteína lag-3 processo de produção composição terapêutica anticorpos anti-idiotipo
DE69636437D1 (de) Ligand polypeptide für hypophyse g-protein gekoppeltes rezeptor-protein, deren herstellung und anwendung
NO20001668D0 (no) Anvendelse av et DNA-fragment, samt komplementære kjeder, derivater og deler derav
ATE306549T1 (de) C-c ckr-1, ein c-c chemokin rezeptor
DE69735716D1 (de) Kappa/mu ähnliche proteintyrosinphosphatase, proteintyrosinphosphatase lambda
TR199901636T2 (xx) �mm�nolojik hastal�klar�n tedavisi i�in terap�tik maddeler olarak ��z�n�r lenfotoksin-beta resept�rleri, anti-lenfotoksin resept�r� antikorlar� ve anti-lenfotoksin ba�� antikorlar�.
EA199900522A1 (ru) Полипептиды, кодируемые геном, подобным гену липазы человека, композиции и методы
Nelson et al. Avian lens spectrin: subunit composition compared with erythrocyte and brain spectrin.
EP0804576A4 (en) Hemopoietin receptor
ES2067541T3 (es) Mejoras en antagonistas de la serotonina y relacionadas con ellos.
EP1456239A4 (en) HYBRID PROTEINS FACED WITH HEPARANSULFATE PROTEOGLYCANE WITH NEUREGULIN-HEPARIN BINDING DOMAIN
EP0635016A4 (en) BENZODIAZEPINE DERIVATIVES AND THEIR CONJUGATES WITH PROTEINS AND POLYPEPTIDES.
ATE273390T1 (de) Säugertier edg-7 rezeptor homologen
DE60043664D1 (de) Dungen davon
DE69631624D1 (de) Antikörper gegen menschliches restrictin
Tanigaki et al. Antigenic Structures of HLA (A, B, C) Antigens: Chymotryptic Glycopeptides Carrying HLA (A, B, C) Determinants
Rosenlöf et al. Radioimmunoassay of haemoglobin F in K 562 cells following induction with renin substrate and erythropoietin

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920805

FG3A Patent granted, date of granting

Effective date: 19990219

NF3A Restitutio in integrum

Free format text: RESTITUTIO IN INTEGRUM

Effective date: 20040213

MM3A Annulment or lapse

Effective date: 20050819