RO70892A - PROCEDURE FOR THE PREPARATION OF 3,4-DIMETHOXY-N- (3- (4-METHOXYPHENYL) -1-METHYL-N-PROPYL) PENETYLAMINE - Google Patents

PROCEDURE FOR THE PREPARATION OF 3,4-DIMETHOXY-N- (3- (4-METHOXYPHENYL) -1-METHYL-N-PROPYL) PENETYLAMINE

Info

Publication number: RO70892A
Authority: RO; Romania
Prior art keywords: penetylamine; dimethoxy; methoxyphenyl; propyl; methyl
Prior art date: 1972-04-12

Application number

RO7383749A

Other languages

French (fr)

Romanian (ro)

Inventor

Ronald R Tuttle

Jack Mills

Original Assignee

Eli Lilly And Co,Us

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-04-12

Filing date

1973-04-12

Publication date

1982-02-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22918877&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO70892(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1973-04-12 Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us

1982-02-26 Publication of RO70892A publication Critical patent/RO70892A/en

Links

GPKUICFDWYEPTK-UHFFFAOYSA-N methoxycyclohexatriene Chemical class COC1=CC=C=C[CH]1 GPKUICFDWYEPTK-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Hospice & Palliative Care (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

RO7383749A 1972-04-12 1973-04-12 PROCEDURE FOR THE PREPARATION OF 3,4-DIMETHOXY-N- (3- (4-METHOXYPHENYL) -1-METHYL-N-PROPYL) PENETYLAMINE RO70892A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US24346672A	1972-04-12	1972-04-12

Publications (1)

Publication Number	Publication Date
RO70892A true RO70892A (en)	1982-02-26

Family

ID=22918877

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
RO7374457A RO65105A (en)	1972-04-12	1973-04-12	PROCEDURE FOR PREPARATION OF DOPAMIN DERIVATIVES
RO7383749A RO70892A (en)	1972-04-12	1973-04-12	PROCEDURE FOR THE PREPARATION OF 3,4-DIMETHOXY-N- (3- (4-METHOXYPHENYL) -1-METHYL-N-PROPYL) PENETYLAMINE

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
RO7374457A RO65105A (en)	1972-04-12	1973-04-12	PROCEDURE FOR PREPARATION OF DOPAMIN DERIVATIVES

Country Status (31)

Country	Link
JP (2)	JPS5825656B2 (en)
KR (1)	KR790000113B1 (en)
AR (1)	AR203822A1 (en)
AT (1)	AT323719B (en)
AU (1)	AU472734B2 (en)
BE (1)	BE798051A (en)
BG (1)	BG23001A3 (en)
CA (1)	CA1018188A (en)
CH (2)	CH580563A5 (en)
CS (2)	CS190448B2 (en)
CY (1)	CY963A (en)
DD (1)	DD107670B3 (en)
DE (1)	DE2317710C2 (en)
DK (1)	DK142750C (en)
ES (1)	ES413639A1 (en)
FR (1)	FR2182947B1 (en)
GB (1)	GB1392674A (en)
HK (1)	HK50178A (en)
HU (2)	HU167597B (en)
IE (1)	IE37511B1 (en)
IL (1)	IL42016A (en)
KE (1)	KE2870A (en)
MY (1)	MY7800381A (en)
NL (1)	NL174459C (en)
PH (1)	PH11041A (en)
PL (2)	PL94207B1 (en)
RO (2)	RO65105A (en)
SE (1)	SE399064B (en)
SU (1)	SU496719A3 (en)
YU (2)	YU36483B (en)
ZA (1)	ZA732136B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH585693A5 (en) *	1974-02-08	1977-03-15	Ciba Geigy Ag
US4342692A (en) *	1980-10-20	1982-08-03	Usv Pharmaceutical Corporation	Pyrrolidines
ZA825227B (en) *	1981-07-22	1984-03-28	Syntex Inc	Substituted pyrrolidine cardiovascular system regulators antihypertensives
JPS6061523A (en) *	1983-09-16	1985-04-09	Shionogi & Co Ltd	Oral dobutamine pharmaceutical
IL85438A0 (en) *	1987-02-24	1988-07-31	Lilly Co Eli	Improvements in or relating to dobutamine salts
JPH0383364U (en) *	1989-12-18	1991-08-23
WO1992020645A1 (en) *	1991-05-20	1992-11-26	Tsumura & Co.	Phellodendrine analogs and allergy type iv suppressor containing the same as active ingredient
EP0620208B1 (en) *	1993-04-13	1997-07-09	Duphar International Research B.V	Production of dobutamine compounds
ATE155125T1 (en) *	1993-04-13	1997-07-15	Duphar Int Res	PRODUCTION OF DOBUTAMIN COMPOUNDS
US7642290B2 (en)	2002-10-03	2010-01-05	Novaremed Limited	Compounds for use in the treatment of autoimmune diseases, immuno-allergical diseases and organ or tissue transplantation rejection
JP4939396B2 (en)	2004-03-26	2012-05-23	ノヴァレメッドリミテッド	Compounds for improving or treating AIDS and other viral diseases and HIV-related infectious diseases and compositions thereof, compositions containing such compounds, methods for treating such diseases and infectious diseases, and methods for producing such compounds and compositions
GB0804213D0 (en)	2008-03-06	2008-04-16	New Era Biotech Ltd	A method of printing or preventing pain
CN102595884B (en)	2009-07-31	2014-12-03	考格尼申治疗股份有限公司	Inhibitors of cognitive decline
US8802734B2 (en)	2009-09-09	2014-08-12	Novaremed Limited	Method of treating or preventing pain
EP2747759A4 (en) *	2011-08-25	2015-05-13	Cognition Therapeutics Inc	Compositions and methods for treating neurodegenerative disease
RU2692258C2 (en)	2014-01-31	2019-06-24	Когнишн Терапьютикс, Инк.	Isoindoline compositions and methods of treating neurodegenerative disease
DK3634394T3 (en)	2017-05-15	2026-03-02	Cognition Therapeutics Inc	COMPOSITIONS FOR TREATING NEUROGENERATE DISEASES
CN114524734B (en) *	2021-12-27	2024-04-26	嘉实（湖南）医药科技有限公司	Preparation method of dobutamine hydrochloride
CN117326958B (en) *	2023-09-21	2025-07-11	锦州奥鸿药业有限责任公司	A preparation method of high-purity dobutamine hydrochloride

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2276619A (en) *		1942-03-17		N-phentlaliphatic-dihtoroxyphentnl

1973
- 1973-03-28 ZA ZA732136A patent/ZA732136B/en unknown
- 1973-04-09 CY CY963A patent/CY963A/en unknown
- 1973-04-09 GB GB1683573A patent/GB1392674A/en not_active Expired
- 1973-04-09 DE DE2317710A patent/DE2317710C2/en not_active Expired
- 1973-04-10 IE IE563/73A patent/IE37511B1/en unknown
- 1973-04-10 FR FR7312845A patent/FR2182947B1/fr not_active Expired
- 1973-04-10 SE SE7305032A patent/SE399064B/en unknown
- 1973-04-11 YU YU00976/73A patent/YU36483B/en unknown
- 1973-04-11 CA CA168,428A patent/CA1018188A/en not_active Expired
- 1973-04-11 AU AU54385/73A patent/AU472734B2/en not_active Expired
- 1973-04-11 SU SU1908277A patent/SU496719A3/en active
- 1973-04-11 BG BG023268A patent/BG23001A3/en unknown
- 1973-04-11 NL NLAANVRAGE7305097,A patent/NL174459C/en not_active IP Right Cessation
- 1973-04-11 BE BE1004956A patent/BE798051A/en not_active IP Right Cessation
- 1973-04-11 CH CH1112475A patent/CH580563A5/xx not_active IP Right Cessation
- 1973-04-11 CH CH517473A patent/CH569691A5/xx not_active IP Right Cessation
- 1973-04-11 DK DK196773A patent/DK142750C/en not_active IP Right Cessation
- 1973-04-11 KR KR7300573A patent/KR790000113B1/en not_active Expired
- 1973-04-11 AT AT318773A patent/AT323719B/en not_active IP Right Cessation
- 1973-04-12 AR AR247523A patent/AR203822A1/en active
- 1973-04-12 PL PL1973183808A patent/PL94207B1/pl unknown
- 1973-04-12 CS CS77171A patent/CS190448B2/en unknown
- 1973-04-12 CS CS732601A patent/CS190406B2/en unknown
- 1973-04-12 HU HUEI552A patent/HU167597B/hu unknown
- 1973-04-12 PL PL1973161874A patent/PL90695B1/pl unknown
- 1973-04-12 RO RO7374457A patent/RO65105A/en unknown
- 1973-04-12 RO RO7383749A patent/RO70892A/en unknown
- 1973-04-12 HU HUEI469A patent/HU166213B/hu unknown
- 1973-04-12 PH PH14508A patent/PH11041A/en unknown
- 1973-04-12 IL IL42016A patent/IL42016A/en unknown
- 1973-04-12 DD DD73170118A patent/DD107670B3/en unknown
- 1973-04-12 ES ES413639A patent/ES413639A1/en not_active Expired
- 1973-04-12 JP JP48041750A patent/JPS5825656B2/en not_active Expired
1978
- 1978-08-10 KE KE2870A patent/KE2870A/en unknown
- 1978-09-07 HK HK501/78A patent/HK50178A/en unknown
- 1978-12-30 MY MY381/78A patent/MY7800381A/en unknown
1979
- 1979-12-28 YU YU3212/79A patent/YU37113B/en unknown
1982
- 1982-08-27 JP JP57149025A patent/JPS58131945A/en active Granted

Also Published As

Publication number	Publication date
CH569691A5 (en)	1975-11-28
AR203822A1 (en)	1975-10-31
NL174459B (en)	1984-01-16
DK142750B (en)	1981-01-12
DE2317710A1 (en)	1973-10-18
AU472734B2 (en)	1976-06-03
SU496719A3 (en)	1975-12-25
DK142750C (en)	1981-08-17
YU36483B (en)	1984-02-29
DD107670A5 (en)	1974-08-12
KR790000113B1 (en)	1979-03-20
IE37511B1 (en)	1977-08-03
JPS497237A (en)	1974-01-22
JPS5825656B2 (en)	1983-05-28
RO65105A (en)	1980-01-15
MY7800381A (en)	1978-12-31
PL94207B1 (en)	1977-07-30
CS190448B2 (en)	1979-05-31
PH11041A (en)	1977-10-25
CH580563A5 (en)	1976-10-15
CA1018188A (en)	1977-09-27
ZA732136B (en)	1974-03-27
YU97673A (en)	1982-02-25
ES413639A1 (en)	1976-01-16
CS190406B2 (en)	1979-05-31
BG23001A3 (en)	1977-05-20
NL7305097A (en)	1973-10-16
FR2182947B1 (en)	1976-07-02
JPS6221343B2 (en)	1987-05-12
YU37113B (en)	1984-08-31
YU321279A (en)	1983-04-27
JPS58131945A (en)	1983-08-06
NL174459C (en)	1984-06-18
SE399064B (en)	1978-01-30
CY963A (en)	1978-12-22
HU166213B (en)	1975-02-28
BE798051A (en)	1973-10-11
AT323719B (en)	1975-07-25
DD107670B3 (en)	1988-04-06
DE2317710C2 (en)	1983-08-04
PL90695B1 (en)	1977-01-31
HU167597B (en)	1975-11-28
GB1392674A (en)	1975-04-30
AU5438573A (en)	1974-10-17
KE2870A (en)	1978-09-01
HK50178A (en)	1978-09-15
IL42016A (en)	1976-05-31
IL42016A0 (en)	1973-06-29
FR2182947A1 (en)	1973-12-14

Publication	Publication Date	Title
AR194587A1 (en)	1973-07-31	PROCEDURE FOR THE PREPARATION OF SUBSTITUTED 2,2'-METHYLENDIPHENOLS
RO70892A (en)	1982-02-26	PROCEDURE FOR THE PREPARATION OF 3,4-DIMETHOXY-N- (3- (4-METHOXYPHENYL) -1-METHYL-N-PROPYL) PENETYLAMINE
SE390819B (en)	1977-01-24	ANALOGICAL PROCEDURE FOR THE PREPARATION OF PIPERAZINYL-PROPYL-1,2,4-TRIAZOLINE DERIVATIVES
SE7710600L (en)	1977-09-21	PROCEDURE FOR THE PREPARATION OF 1,3-BENZOXAZOLES
DK134177C (en)	1977-02-28	PROCEDURE FOR THE PREPARATION OF 3- (PIPERAZINOALKYL) -PYRAZOLES
AR204926A1 (en)	1976-03-19	PROCEDURE FOR THE PREPARATION OF 2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINE
AR192786A1 (en)	1973-03-14	PROCEDURE FOR THE PREPARATION OF NEW N-AMINE-TERTIARY-METHYL-4'DIBENZO (B, E) OXEPINE-11-SPIRO-2'DIOXOLANOS-1 ', 3'
AR200007A1 (en)	1974-10-15	PROCEDURE FOR THE PREPARATION OF NEW OXAZOLES 2,4,5-TRISUSTITUIDOS
SE395460B (en)	1977-08-15	PROCEDURE FOR THE PREPARATION OF 2BETA, 16BETA-DIPIPERIDINO-5ALFA-ANDROSTANES
AR208393A1 (en)	1976-12-27	PROCEDURE FOR THE PREPARATION OF 2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINE
SE400768B (en)	1978-04-10	PROCEDURE FOR THE PREPARATION OF 2-PHENYL-6-SULFAMOYL-7-CHLORO-1,2,3,4-TETRAHYDRO-4-CHINAZOLINONE
AR211929A1 (en)	1978-04-14	PROCEDURE FOR THE PREPARATION OF 7-ACETYL-ALPHA- (TER.BUTYLAMINOMETHYL) -2-BENZOFURANMETHANOL
SE431451B (en)	1984-02-06	PROCEDURE FOR THE PREPARATION OF 2,3-DIHYDROXIPROPOXICINOLINES OR ISOKINOLINES
BG20583A3 (en)	1975-12-05	METHOD FOR THE PREPARATION OF 2,6-DIAMINO-DIHYDROPYRIDINES
SE420603B (en)	1981-10-19	PROCEDURE FOR THE PREPARATION OF METHYL-3- (2-CHINOXOLINYLMETHYL) -CARBAZATE-N? 721, N? 724-DIOXIDE
AR199826A1 (en)	1974-09-30	PROCEDURE FOR THE PREPARATION OF OXAZOLES 2,4,5-TRISUSTITUIDOS
AR201114A1 (en)	1975-02-14	PROCEDURE FOR THE PREPARATION OF NEW AZA -10,11-DIHIDRO 5-H-DIBENZO <B, E> - <1,4> -DIAZEPINAS
DK131855C (en)	1976-02-16	PROCEDURE FOR THE PREPARATION OF 3,4-DIHYDROPYRIDONES
AR197040A1 (en)	1974-03-08	PROCEDURE FOR THE PREPARATION OF NEW BIPHENYLACETAMIDES
AR200162A1 (en)	1974-10-24	PROCEDURE FOR THE PREPARATION OF 1,2,4-TRIAZOLIC DERIVATIVES
DK132831C (en)	1976-07-12	ANALOGICAL PROCEDURE FOR THE PREPARATION OF 17BETA-HYDROXY-2,2,17-TRIMETHYL-4-ANDROSTEN-3-ON
NO137725C (en)	1978-04-12	PROCEDURE FOR SELECTIVE PREPARATION OF 1,2-DICHLOROETANE
DK132329C (en)	1976-05-03	PROCEDURE FOR THE PREPARATION OF CARDENOLID-3, ALFA- (2'-DESOXY-GLYCOSIDES)
AR192452A1 (en)	1973-02-21	PROCEDURE FOR THE PREPARATION OF AMINOALCAMIDES 2,2-DISUBSTITUED COMPOUNDS
NO782754L (en)	1973-08-14	ANALOGICAL PROCEDURE FOR THE PREPARATION OF 15ALFA, 16ALFA-METHYLENE-4-OESTREN-17BETA-OLEN