RO81223B - Process for preparing some derivatives of 1-cyclohexyle-4-aryl-pyperidincarboxylic acid - Google Patents
Process for preparing some derivatives of 1-cyclohexyle-4-aryl-pyperidincarboxylic acidInfo
- Publication number
- RO81223B RO81223B RO103173A RO10317381A RO81223B RO 81223 B RO81223 B RO 81223B RO 103173 A RO103173 A RO 103173A RO 10317381 A RO10317381 A RO 10317381A RO 81223 B RO81223 B RO 81223B
- Authority
- RO
- Romania
- Prior art keywords
- aryl
- general formula
- derivatives
- pyperidincarboxylic
- cyclohexyle
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 239000003610 charcoal Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
Landscapes
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Inventia se refera la un procedeu pentru prepararea unor derivati al acidului 1-ciclohexil-4-aril-piperidincarboxilic, cu formula generala I: (vezi formula) în care r reprezinta o grupa hidroxi alchiloxi inferior aril alchiloxi inferior, R1 reprezinta hidrogen sau alchil inferior, Ar1 si Ar2, reprezinta aril tienil sau piridinil, prin reactia unui compus cu formula generala II: 8vezi formula) cu un compus cu formula generala III: (vezi formula) prin hidrogenarea catalitica în prezenta unui catalizator de paladiu sau platina pe suport de carbune.The invention relates to a process for the preparation of 1-cyclohexyl-4-aryl-piperidinecarboxylic acid derivatives of the general formula I wherein R represents a lower alkoxy lower alkyl lower alkyloxy group, R 1 represents hydrogen or lower alkyl , Ar 1 and Ar 2 represent aryl thienyl or pyridinyl by reacting a compound of the general formula II with a compound of the general formula III by catalytic hydrogenation in the presence of a palladium or platinum catalyst on a charcoal support .
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11492480A | 1980-01-24 | 1980-01-24 | |
| US19163580A | 1980-09-29 | 1980-09-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO81223A RO81223A (en) | 1983-02-15 |
| RO81223B true RO81223B (en) | 1983-02-28 |
Family
ID=26812675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO103173A RO81223B (en) | 1980-01-24 | 1981-01-21 | Process for preparing some derivatives of 1-cyclohexyle-4-aryl-pyperidincarboxylic acid |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO81223B (en) |
-
1981
- 1981-01-21 RO RO103173A patent/RO81223B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO81223A (en) | 1983-02-15 |
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