RO81639B1 - Procedeu de obtinere a unei pulberi suspendabile orale de trihidrat de ampicilina - Google Patents
Procedeu de obtinere a unei pulberi suspendabile orale de trihidrat de ampicilinaInfo
- Publication number
- RO81639B1 RO81639B1 RO103546A RO10354681A RO81639B1 RO 81639 B1 RO81639 B1 RO 81639B1 RO 103546 A RO103546 A RO 103546A RO 10354681 A RO10354681 A RO 10354681A RO 81639 B1 RO81639 B1 RO 81639B1
- Authority
- RO
- Romania
- Prior art keywords
- trihydrate
- ampicilin
- suspendable
- preparing
- oral powder
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940042126 oral powder Drugs 0.000 title 1
- 150000004684 trihydrates Chemical class 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- 241000416162 Astragalus gummifer Species 0.000 abstract 1
- UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 229920001615 Tragacanth Polymers 0.000 abstract 1
- 229960000723 ampicillin Drugs 0.000 abstract 1
- 229960003311 ampicillin trihydrate Drugs 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940100692 oral suspension Drugs 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 abstract 1
- 229960001462 sodium cyclamate Drugs 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 229940116362 tragacanth Drugs 0.000 abstract 1
- 235000010487 tragacanth Nutrition 0.000 abstract 1
- 239000000196 tragacanth Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
Procedeu de obtinere a pulberi suspendabile orale hidrat de ampicilina, care, în scopul asigurarii stabilitatii trihidratului de amplicilina, disperseaza principiul activ cu ajutorul amestecului de lactoza si zahar apoi se suspenda cu ajutorul pulberii de tragcanta într-un raport de 7,2...9,5 : 5,4....6,5%, se amesteca, în continuare cu acid ascorbic 0,8......1,1% ciclamat de sodiu sau zaharina sodica 1...1,5%, pulbere suspendabila obtinuta fiind iradiata cu radiatii omega de Co la puterea 60 la doza de 2 MR.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO81103546A RO81639A2 (ro) | 1981-02-27 | 1981-02-27 | Procedeu de obtinere a unei pulberi suspendabile oxrale de ampicilina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO81103546A RO81639A2 (ro) | 1981-02-27 | 1981-02-27 | Procedeu de obtinere a unei pulberi suspendabile oxrale de ampicilina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO81639B1 true RO81639B1 (ro) | 1983-05-30 |
| RO81639A2 RO81639A2 (ro) | 1983-06-01 |
Family
ID=20109633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO81103546A RO81639A2 (ro) | 1981-02-27 | 1981-02-27 | Procedeu de obtinere a unei pulberi suspendabile oxrale de ampicilina |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO81639A2 (ro) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9930058D0 (en) * | 1999-12-20 | 2000-02-09 | Novartis Ag | Organic compounds |
-
1981
- 1981-02-27 RO RO81103546A patent/RO81639A2/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO81639A2 (ro) | 1983-06-01 |
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