RO86591B1 - Derivat de 1,3-dimetilxantina si procedeu de prepararea a acestuia - Google Patents
Derivat de 1,3-dimetilxantina si procedeu de prepararea a acestuiaInfo
- Publication number
- RO86591B1 RO86591B1 RO110690A RO11069083A RO86591B1 RO 86591 B1 RO86591 B1 RO 86591B1 RO 110690 A RO110690 A RO 110690A RO 11069083 A RO11069083 A RO 11069083A RO 86591 B1 RO86591 B1 RO 86591B1
- Authority
- RO
- Romania
- Prior art keywords
- dimethylxanthine
- dimethylformamide
- preparing
- same
- soluble
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical class O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 229960000278 theophylline Drugs 0.000 abstract 1
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Inventia se refera la un derivat de 1,3-dimetilxantinei care are formula structurala I: (vezi formula) si este o pulbere de culoare alba cu punct de topire 282...284 degree C solubila în apa, etanol 50 degree , acid acetic glacial, solubila la cald în dimetilformamida. Procedeul pentru prepararea derivatului consta în tratarea sarii de sodiu a 1,3-dimetilxantinei cu gama-bromacetilacetatul de etil în dimetilformamida la temperatura de reflux, se filtreaza solutia fierbinte si se raceste filtratul, separat prin esorarea precipitatului se usuca acesta la temperatura camerei se purifica si se recristalizeaza din etanol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO110690A RO86591B1 (ro) | 1983-04-19 | 1983-04-19 | Derivat de 1,3-dimetilxantina si procedeu de prepararea a acestuia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO110690A RO86591B1 (ro) | 1983-04-19 | 1983-04-19 | Derivat de 1,3-dimetilxantina si procedeu de prepararea a acestuia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO86591A2 RO86591A2 (ro) | 1985-04-17 |
| RO86591B1 true RO86591B1 (ro) | 1985-05-02 |
Family
ID=20112943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO110690A RO86591B1 (ro) | 1983-04-19 | 1983-04-19 | Derivat de 1,3-dimetilxantina si procedeu de prepararea a acestuia |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO86591B1 (ro) |
-
1983
- 1983-04-19 RO RO110690A patent/RO86591B1/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO86591A2 (ro) | 1985-04-17 |
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