RO95663B1 - Procedeu de obtinere a unei proteine biologic active - Google Patents
Procedeu de obtinere a unei proteine biologic activeInfo
- Publication number
- RO95663B1 RO95663B1 RO122323A RO12232386A RO95663B1 RO 95663 B1 RO95663 B1 RO 95663B1 RO 122323 A RO122323 A RO 122323A RO 12232386 A RO12232386 A RO 12232386A RO 95663 B1 RO95663 B1 RO 95663B1
- Authority
- RO
- Romania
- Prior art keywords
- growth hormone
- codons
- obtaining
- biologically active
- active protein
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 108020004705 Codon Proteins 0.000 abstract 4
- 239000000122 growth hormone Substances 0.000 abstract 4
- 108010051696 Growth Hormone Proteins 0.000 abstract 3
- 102000018997 Growth Hormone Human genes 0.000 abstract 3
- 108010006025 bovine growth hormone Proteins 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 241000282887 Suidae Species 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 210000003705 ribosome Anatomy 0.000 abstract 1
- 239000004474 valine Substances 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Inventia se refera la un procedeu de obtinere a unei proteine biologic active, de tipul hormon de crestere bovin, hormon de crestere porcin sau variante ale acestora, care prevede obtinerea unui vector recombinant continând un promotor, un sit de legatura ribozomal, 1 ... 3 codoni contigui de metionina, unul din acesti codoni având rol de semnal start al translatiei, urmati imediat de codonii hormonului de crestere bovin N-leucina, ai hormonului de crestere bovin N-valina sau ai hormonului de crestere suin N-alanina si de un codon stop al translatiei si utilizarea acestui vector pentru obtinerea hormonului de crestere cu continut mai mare de 80% polipeptida N-alanina. Hormonii de crestere, obtinuti conform inventiei, se pot utiliza cu succes pentrumarirea productiei de lapte la vaci si pentru potentarea cresterii la porci.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO122323A RO95663B1 (ro) | 1986-02-21 | 1986-02-21 | Procedeu de obtinere a unei proteine biologic active |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO122323A RO95663B1 (ro) | 1986-02-21 | 1986-02-21 | Procedeu de obtinere a unei proteine biologic active |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RO95663B1 true RO95663B1 (ro) | 1988-10-31 |
Family
ID=40904845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO122323A RO95663B1 (ro) | 1986-02-21 | 1986-02-21 | Procedeu de obtinere a unei proteine biologic active |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO95663B1 (ro) |
-
1986
- 1986-02-21 RO RO122323A patent/RO95663B1/ro unknown
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