RS59896B1 - Kompozicije nanočestica bez priona i postupci povezani sa njima - Google Patents
Kompozicije nanočestica bez priona i postupci povezani sa njimaInfo
- Publication number
- RS59896B1 RS59896B1 RS20191601A RSP20191601A RS59896B1 RS 59896 B1 RS59896 B1 RS 59896B1 RS 20191601 A RS20191601 A RS 20191601A RS P20191601 A RSP20191601 A RS P20191601A RS 59896 B1 RS59896 B1 RS 59896B1
- Authority
- RS
- Serbia
- Prior art keywords
- heater
- electrode
- liquid
- electrodes
- prion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2828—Prion diseases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S210/00—Liquid purification or separation
- Y10S210/902—Materials removed
- Y10S210/903—Nitrogenous
- Y10S210/905—Protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Optics & Photonics (AREA)
- Inorganic Chemistry (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
Description
II OPIS PRONALASKA
NAZIV PRONALASKA: ELEKTRODNI TROFAZNI GREJAČ
a) Oblast tehnike na koju se pronalazak odnosi
Pronalazak se odnosi na oblast termotehnike koja se bavi zagrevanjem elektro
provodnih tečnosti u polju naizmenične struje.
b) Tehnički problem
Potrebno je zagrejati elektro provodnu tečnost za: grejanje, procesnu
opremu, toplu potrošnu vodu i paru trofaznom naizmeničnom strujom.
c) Stanje tehnike
Sadašnji nivo tehnike za grejanje elektro provodnih tečnosti je takozvani
potopljeni grejač koji se sastoji od: elektrootporne žice koja se zagreva proticanjem naizmenične struje, a toplotu prenosi na šamotno brašno u koje je utopljena i na cev sa kojim je grejač oplašten. Ovakva konstrukcija ima sledeće nedostatke: sporo zagrevanje, pregorevanje grejača kada nema tečnosti, utrošak veće količine energije zbog zagrevanja samog grejača.
d) Izlaganje suštine pronalaska
Elektroprovodna tečnost ulazi kroz otvore 9, zatim zalazi izmedju
elektroda 1 gde se u polju naizmenične struje zagreva i zatim izlazi kroz otvore 8. Ukoliko je položaj montaže elektrodnog trofaznog grejača drugačiji od onog na slici 1. tada su ulazni otvori 8, a izlazni otvori su 9-
e) Kratak opis slika nacrta
Pronalazak je detaljno opis na primeru načina izvodjenja prikazanom na
nacrtu u kome:
Slika 1. - Prikazuje vertikalni presek elektrodnog trofaznog grejača;
Slika 2. - Prikazuje horizonltalni presek A-A elektrodnog trofaznog
grejača;
Slika 3-- Prikazuje horizontalni presek B-B elektrodnog trofaznog grejača;
f) Detaljan opis pronalska
Elektroprovodna tečnost koja ulazi kroz pet otvora 9 kape od plastičnog
materijala 6 zalazi izmedju tri komada elektroda 1 u obliku nezatvorenih pravouglih profila koji zalaze jedan u drugi. Ove tri elektrode 1 ulivene su u plastično telo 5. U polju naizmenične struje izmedju elektroda 1 elektrootporna tečnost se zagreva i izlazi kroz otvore 8 plastične kape 6.
Tri elektrode 1 su preko kontakt zavrtnja 3 i klema 4, vezane za tri
faze naizmenične struje.
Telo od plastike 5 ima navoj sa kojim se navrče na sud u kome greje elektro-otpornu tečnost i ima zaptivni gumeni prsten 7 kojim se onemogučava isticanje tečnosti van suda.
Plastična kapa 6 sa svojim otvorima 8 i 9 usmerava proticanje tečnosti
za grejanje i onemogućava mehaničkim nečistoćama da dodju izmedju elektroda. Plastična kapa 6 ima naglavne zube sa kojima se vezuje za plastično telo 5-Trofazni elektrodni grejač može da se montira u bilo kom položaju. Način uzemljenja ovih elektrodnih grejača je isti kao kod klasičnih grejača.
g) Način industrijske ili druge primene pronalaska
Elektordni trofazni grejač može da se primeni za zagrevanje elektroprovodnih
tečnosti ili proizvodnju pare kod sledečih uredjaja:
- kotlova,
- radijatora,
- bojlera, - reakcionih posuda,
- konvektora i kalorifera,
- fen-coill-a itd
Claims (1)
- Elektrodni trofazni grejač karakterisan je time što se električno naizmenično polje uspostavlja izmedju elektroda kroz elektroprovodnu tečnost što u slučaju smanjenja nivoa tečnosti (ili nestanka tečnosti) izaziva smanjenje kapaciteta grejača (ili potpuni prestanak njegovog rada). Elektrodni trofazni grejač karakterisan je time što su mu elektrode izvedene u obliku nezatvorenih pravougaonih profila koji zalaze jedan u drugi, čime je maksimalno povečana medjusobna površina tj. naizmenično električno polje, a dimenzije grejača su smanjene na minimum.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16966509P | 2009-04-15 | 2009-04-15 | |
| US23805209P | 2009-08-28 | 2009-08-28 | |
| PCT/US2010/031197 WO2010121000A1 (en) | 2009-04-15 | 2010-04-15 | Prion-free nanoparticle compositions and methods |
| EP10765167.1A EP2419732B1 (en) | 2009-04-15 | 2010-04-15 | Prion-free nanoparticle compositions and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS59896B1 true RS59896B1 (sr) | 2020-03-31 |
Family
ID=42982852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20191601A RS59896B1 (sr) | 2009-04-15 | 2010-04-15 | Kompozicije nanočestica bez priona i postupci povezani sa njima |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US20100297243A1 (sr) |
| EP (2) | EP2419732B1 (sr) |
| JP (3) | JP5781500B2 (sr) |
| KR (1) | KR20120044279A (sr) |
| CN (1) | CN102460167B (sr) |
| AU (1) | AU2010236382B2 (sr) |
| BR (1) | BRPI1012525A2 (sr) |
| CA (1) | CA2758913A1 (sr) |
| CY (1) | CY1122617T1 (sr) |
| DK (1) | DK2419732T3 (sr) |
| ES (1) | ES2764100T3 (sr) |
| HR (1) | HRP20192259T1 (sr) |
| HU (1) | HUE047376T2 (sr) |
| IL (1) | IL215765A (sr) |
| LT (1) | LT2419732T (sr) |
| ME (1) | ME03596B (sr) |
| MX (2) | MX378130B (sr) |
| MY (1) | MY175260A (sr) |
| PL (1) | PL2419732T3 (sr) |
| PT (1) | PT2419732T (sr) |
| RS (1) | RS59896B1 (sr) |
| RU (1) | RU2559570C2 (sr) |
| SG (1) | SG175239A1 (sr) |
| SI (1) | SI2419732T1 (sr) |
| SM (1) | SMT201900751T1 (sr) |
| WO (1) | WO2010121000A1 (sr) |
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| US8137684B2 (en) * | 1996-10-01 | 2012-03-20 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| US20030199425A1 (en) * | 1997-06-27 | 2003-10-23 | Desai Neil P. | Compositions and methods for treatment of hyperplasia |
| LT1585548T (lt) | 2002-12-09 | 2018-09-25 | Abraxis Bioscience, Llc | Farmakologinių agentų kompozicijos ir įvedimo būdai |
| US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| NZ595313A (en) | 2005-02-18 | 2013-03-28 | Abraxis Bioscience Llc | The Use Of Nanoparticles Comprising Rapamycin Or Taxane In The Treatment Of Proliferative Diseases |
| CA2880727C (en) | 2005-08-31 | 2019-05-07 | Neil P. Desai | Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents |
| CA2672618C (en) | 2006-12-14 | 2021-03-02 | Abraxis Bioscience, Llc | Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane |
| KR20150002886A (ko) | 2007-03-07 | 2015-01-07 | 아브락시스 바이오사이언스, 엘엘씨 | 항암제로서 라파마이신 및 알부민을 포함하는 나노입자 |
| EP3326630A3 (en) * | 2007-05-03 | 2018-08-29 | Abraxis BioScience, LLC | Methods and compositions for treating pulmonary hypertension |
| AU2008260447B2 (en) | 2007-06-01 | 2013-10-10 | Abraxis Bioscience, Llc | Methods and compositions for treating recurrent cancer |
| WO2009126401A1 (en) * | 2008-04-10 | 2009-10-15 | Abraxis Bioscience, Llc | Compositions of hydrophobic taxane derivatives and uses thereof |
| PT2419732T (pt) | 2009-04-15 | 2019-12-24 | Abraxis Bioscience Llc | Composições e métodos de nanopartículas isentas de priões |
| PL2552438T3 (pl) | 2010-03-26 | 2016-12-30 | Sposoby leczenia raka wątrobowokomórkowego | |
| BR112012024590A2 (pt) | 2010-03-29 | 2016-05-31 | Abraxis Bioscience Inc | métodos de reforço da liberação de fármaco e da eficácia de agentes terapêuticos |
| RU2016119999A (ru) | 2010-03-29 | 2018-11-08 | АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи | Способы лечения онкологических заболеваний |
| JP6257324B2 (ja) | 2010-06-04 | 2018-01-10 | アブラクシス バイオサイエンス， エルエルシー | 膵臓がんの処置方法 |
| GB2503163B (en) | 2011-03-22 | 2019-05-29 | Nant Holdings Ip Llc | Reasoning Engines |
| CA3063641A1 (en) | 2011-04-28 | 2012-11-01 | Abraxis Bioscience, Llc | Intravascular delivery of nanoparticle compositions and uses thereof |
| SMT201900502T1 (it) | 2011-12-14 | 2019-11-13 | Abraxis Bioscience Llc | Uso di eccipienti polimerici per la liofilizzazione o il congelamento di particelle |
| WO2013115559A1 (ko) * | 2012-01-30 | 2013-08-08 | 성균관대학교 산학협력단 | 수난용성 약물을 내부에 포함하는 알부민 나노입자 제조방법 |
| US9149455B2 (en) | 2012-11-09 | 2015-10-06 | Abraxis Bioscience, Llc | Methods of treating melanoma |
| US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
| JP6349381B2 (ja) | 2013-03-12 | 2018-06-27 | アブラクシス バイオサイエンス， エルエルシー | 肺がんを処置する方法 |
| NZ630213A (en) | 2013-03-14 | 2017-05-26 | Abraxis Bioscience Llc | Methods of treating bladder cancer |
| US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
| US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
| JP6987644B2 (ja) | 2015-06-29 | 2022-01-05 | アブラクシス バイオサイエンス， エルエルシー | 類上皮細胞腫瘍を処置する方法 |
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