RU2003123723A - DERIVATIVES 2-H-1-BENZOPIRAN-2-IT, MANIFESTING ANTI-Calcium ACTIVITY - Google Patents

DERIVATIVES 2-H-1-BENZOPIRAN-2-IT, MANIFESTING ANTI-Calcium ACTIVITY Download PDF

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RU2003123723A
RU2003123723A RU2003123723/04A RU2003123723A RU2003123723A RU 2003123723 A RU2003123723 A RU 2003123723A RU 2003123723/04 A RU2003123723/04 A RU 2003123723/04A RU 2003123723 A RU2003123723 A RU 2003123723A RU 2003123723 A RU2003123723 A RU 2003123723A
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Prior art keywords
derivatives
benzopiran
calcium activity
manifesting
manifesting anti
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RU2003123723/04A
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RU2242471C1 (en
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Азад Зи д оглы Абышев (RU)
Азад Зияд Оглы Абышев
Эльсевер Мамед оглы Агаев (RU)
Эльсевер Мамед Оглы Агаев
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Азад Зи д оглы Абышев (RU)
Азад Зияд Оглы Абышев
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Claims (1)

Производные 2-Н-1-бензопиран-2-она общей формулы IDerivatives of 2-H-1-benzopyran-2-one of general formula I
Figure 00000001
Figure 00000001
 где: R=-СН3, R1=-NH-(CH2)2-Br(1); R=-СН3, R1=-NH-(СН2)3-Cl (2);where: R = —CH 3 , R 1 = —NH— (CH 2 ) 2 —Br (1); R = -CH 3 , R 1 = -NH- (CH 2 ) 3 -Cl (2); R=-СН3, R1=-O-(CH2)2-Br(3); R=-СН3, R1=-O-(СН2)3-Cl (4);R = -CH 3 , R 1 = -O- (CH 2 ) 2 -Br (3); R = -CH 3 , R 1 = -O- (CH 2 ) 3 -Cl (4); R=-Н, R1=-O-(CH2)2-Br(5); R=-Н, R1=-O-(СН2)3-Cl (6);R = -H, R 1 = -O- (CH 2 ) 2 -Br (5); R = -H, R 1 = -O- (CH 2 ) 3 -Cl (6); R=-O-(CH2)2-Br, R1=-H(7); R=-O-(СН2)3-Cl, R1=-H(8);R = -O- (CH 2 ) 2 -Br, R 1 = -H (7); R = -O- (CH 2 ) 3 -Cl, R 1 = -H (8); R=-Н, R1=-O-(CH2)2-OH(9); R=-H, R1=-O-(СН2)2-SH (10);R = -H, R 1 = -O- (CH 2 ) 2 -OH (9); R = -H, R 1 = -O- (CH 2 ) 2 -SH (10); R=-H, R1=-O-(CH2)2-NH2(11); R=-СН3, R1=-O-(CH2)2-NH2(12);R = -H, R 1 = -O- (CH 2 ) 2 -NH 2 (11); R = -CH 3 , R 1 = -O- (CH 2 ) 2 -NH 2 (12); R=-CH3, R1=-O-(CH2)2-O-(CH2)2-OH(13);R = -CH 3 , R 1 = -O- (CH 2 ) 2 -O- (CH 2 ) 2 -OH (13); R=-H, R1=-O-(CH2)2-O-(CH2)2-OH(14);R = -H, R 1 = -O- (CH 2 ) 2 -O- (CH 2 ) 2 -OH (14);
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 проявляющие антикальциевую активность.showing anti-calcium activity.
RU2003123723/04A 2003-07-31 2003-07-31 Derivatives of 2-h-1-benzopyrane-2-one eliciting anti-calcium activity RU2242471C1 (en)

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WO2004027378A2 (en) 2002-09-20 2004-04-01 Promega Corporation Luminescence-based methods and probes for measuring cytochrome p450 activity
WO2006102958A1 (en) * 2005-03-29 2006-10-05 Newron Pharmaceuticals S.P.A. Substituted aminoalkyl- and amidoalkyl-benzopyran derivatives
JP5597200B2 (en) 2008-08-18 2014-10-01 プロメガ コーポレイション Compounds producing luminescence and methods for detecting cytochrome P4503A enzyme
RU2427368C1 (en) * 2010-03-05 2011-08-27 Государственное образовательное учреждение высшего профессионального образования САНКТ-ПЕТЕРБУРГСКАЯ ГОСУДАРСТВЕННАЯ ХИМИКО-ФАРМАЦЕВТИЧЕСКАЯ АКАДЕМИЯ Федерального агентства по здравоохранению и социальному развитию (ГОУ ВПО СПХФА Росздрава) Antiarrhythmic medication based on 4-methyl-7,7'-ethylenedioxy-2h-1-dibenzopyran-2,2'-dione
RU2452732C2 (en) * 2010-03-31 2012-06-10 Петр Прокофьевич Денисенко Chloropropoxy derivatives of 7-oxo-coumarin, having tranquilising and hepatoprotective action
US9790537B2 (en) 2014-01-29 2017-10-17 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
CN104829601B (en) * 2015-03-19 2018-04-27 中国科学院兰州化学物理研究所 A kind of coumarin derivative and its preparation method and application
RU2678969C1 (en) * 2018-03-28 2019-02-05 Общество С Ограниченной Ответственностью "Сир" Antiarrhythmic drug based on hybrid molecules of amlodipine with (7-methoxicumarin-4-yl)acetic acid
RU2677647C1 (en) * 2018-03-28 2019-01-18 Общество С Ограниченной Ответственностью "Сир" Anticoagulant agent of indirectly action based on new hybrid molecule of warfarin with essential acid
RU2672062C1 (en) * 2018-05-07 2018-11-09 Общество С Ограниченной Ответственностью "Сир" Hybrid coumarins with indirect anticoagulant action

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SU1836086A3 (en) * 1988-12-26 1993-08-23 Лehиhгpaдckий Haучho-Иccлeдobateльckий Иhctиtуt Bakциh И Cыbopotok The substance possessing a tranquilising activity
AU5626494A (en) * 1992-11-27 1994-06-22 Byk Nederland Bv Nitroxy compounds with pharmaceutical properties
RU2155036C2 (en) * 1998-11-11 2000-08-27 Азад Зияд Оглы Абышев Agent for treatment of patient with heart ischemic disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2277872A1 (en) * 2005-05-31 2011-01-26 Promega Corporation Luminogenic and fluorogenic compounds and methods to detect molecules or conditions

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