RU2019109263A3 - - Google Patents

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Publication number
RU2019109263A3
RU2019109263A3 RU2019109263A RU2019109263A RU2019109263A3 RU 2019109263 A3 RU2019109263 A3 RU 2019109263A3 RU 2019109263 A RU2019109263 A RU 2019109263A RU 2019109263 A RU2019109263 A RU 2019109263A RU 2019109263 A3 RU2019109263 A3 RU 2019109263A3
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RU
Russia
Application number
RU2019109263A
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Russian (ru)
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RU2776918C2 (ru
RU2019109263A (ru
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Publication of RU2019109263A publication Critical patent/RU2019109263A/ru
Publication of RU2019109263A3 publication Critical patent/RU2019109263A3/ru
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Publication of RU2776918C2 publication Critical patent/RU2776918C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2019109263A 2016-09-07 2017-09-06 2'-замещенные-n6-замещенные пуриновые нуклеотиды для лечения вызванных рнк-вирусом заболеваний RU2776918C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662384664P 2016-09-07 2016-09-07
US62/384,664 2016-09-07
PCT/US2017/050323 WO2018048937A1 (en) 2016-09-07 2017-09-06 2'-substituted-n6-substituted purine nucleotides for rna virus treatment

Publications (3)

Publication Number Publication Date
RU2019109263A RU2019109263A (ru) 2020-10-08
RU2019109263A3 true RU2019109263A3 (2) 2020-12-29
RU2776918C2 RU2776918C2 (ru) 2022-07-28

Family

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Also Published As

Publication number Publication date
JP2019526596A (ja) 2019-09-19
KR102456417B1 (ko) 2022-10-19
US10946033B2 (en) 2021-03-16
US11975016B2 (en) 2024-05-07
HRP20220278T1 (hr) 2022-05-13
DK3512863T3 (da) 2022-03-07
EP4088725A1 (en) 2022-11-16
US20230017958A1 (en) 2023-01-19
EA201990628A1 (ru) 2019-09-30
ZA202106848B (en) 2025-01-29
CN116036114A (zh) 2023-05-02
US20200222442A1 (en) 2020-07-16
CA3034648A1 (en) 2018-03-15
AU2020220216A1 (en) 2020-09-10
EA202190602A3 (ru) 2021-11-30
RU2019109263A (ru) 2020-10-08
MY197236A (en) 2023-06-07
EA202190602A2 (ru) 2021-06-30
EP3865136A1 (en) 2021-08-18
BR112019004297A2 (pt) 2019-05-28
WO2018048937A1 (en) 2018-03-15
SI3512863T1 (sl) 2022-04-29
KR20200106561A (ko) 2020-09-14
EP3512863A1 (en) 2019-07-24
RS62943B1 (sr) 2022-03-31
AU2020220216B2 (en) 2022-05-19
AU2017324939B2 (en) 2021-10-14
AU2022215185A1 (en) 2022-09-01
SMT202200072T1 (it) 2022-03-21
HUE057743T2 (hu) 2022-06-28
CN109689672B (zh) 2023-05-30
CN109689672A (zh) 2019-04-26
US20190201433A1 (en) 2019-07-04
JP7124024B2 (ja) 2022-08-23
KR20220146668A (ko) 2022-11-01
PT3512863T (pt) 2022-03-09
JP2022068329A (ja) 2022-05-09
ZA201901061B (en) 2021-06-30
ES2907874T3 (es) 2022-04-26
CA3034648C (en) 2023-02-28
EP3512863B1 (en) 2021-12-08
KR20190043602A (ko) 2019-04-26
PL3512863T3 (pl) 2022-04-04
JP2021001202A (ja) 2021-01-07
SG11201901457TA (en) 2019-03-28
EP3512863A4 (en) 2020-06-03
CA3187650A1 (en) 2018-03-15
JP2023171730A (ja) 2023-12-05
AU2017324939A1 (en) 2019-03-21
CY1125163T1 (el) 2023-06-09
EA037868B1 (ru) 2021-05-28
LT3512863T (lt) 2022-03-10

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